Inventor
WYATT JACQUELINE
US41 patents
Patents
41 patentsUS6365354B1Apr 2, 2002
Antisense modulation of lysophospholipase I expression
ISIS PHARMACEUTICALS INC366 citations99
US6444464B1Sep 3, 2002
Antisense modulation of E2F transcription factor 2 expression
ISIS PHARMACEUTICALS INC115 citations98
US6287860B1Sep 11, 2001
Antisense inhibition of MEKK2 expression
ISIS PHARMACEUTICALS INC334 citations98
US6261840B1Jul 17, 2001
Antisense modulation of PTP1B expression
ISIS PHARMACEUTICALS INC98 citations98
US6455307B1Sep 24, 2002
Antisense modulation of casein kinase 2-alpha prime expression
ISIS PHARMACEUTICALS INC25 citations93
US6329203B1Dec 11, 2001
Antisense modulation of glioma-associated oncogene-1 expression
ISIS PHARMACEUTICALS INC32 citations93
US6265216B1Jul 24, 2001
Antisense modulation of cot oncogene expression
ISIS PHARMACEUTICALS INC29 citations93
US6602857B1Aug 5, 2003
Antisense modulation of PTP1B expression
ISIS PHARMACEUTICALS INC32 citations92
US6372433B1Apr 16, 2002
Antisense modulation of inhibitor of DNA binding-1 expression
ISIS PHARMACEUTICALS INC22 citations92
US5698391ADec 16, 1997
Methods for synthetic unrandomization of oligomer fragments
ISIS PHARMACEUTICALS INC36 citations92
US6379960B1Apr 30, 2002
Antisense modulation of damage-specific DNA binding protein 2, p48 expression
ISIS PHARMACEUTICALS INC32 citations91
US6503754B1Jan 7, 2003
Antisense modulation of BH3 interacting domain death agonist expression
ISIS PHARMACEUTICALS INC17 citations84
US6271030B1Aug 7, 2001
Antisense inhibition of C/EBP beta expression
ISIS PHARMACEUTICALS INC17 citations84
US6187545B1Feb 13, 2001
Antisense modulation of pepck-cytosolic expression
ISIS PHARMACEUTICALS INC17 citations84
US6607916B2Aug 19, 2003
Antisense inhibition of Casein kinase 2-alpha expression
ISIS PHARMACEUTICALS INC9 citations74
US6602713B1Aug 5, 2003
Antisense modulation of protein phosphatase 2 catalytic subunit beta expression
ISIS PHARMACEUTICALS INC7 citations74
US6498035B1Dec 24, 2002
Antisense modulation of MEKK3 expression
ISIS PHARMACEUTICALS INC10 citations74
US6444465B1Sep 3, 2002
Antinsense modulation of Her-1 expression
ISIS PHARMACEUTICALS INC13 citations74
US6440738B1Aug 27, 2002
Antisense modulation of casein kinase 2-beta expression
ISIS PHARMACEUTICALS INC12 citations74
US6323029B1Nov 27, 2001
Antisense modulation of glycogen synthase kinase 3 beta expression
ISIS PHARMACEUTICALS INC12 citations74
US6316259B1Nov 13, 2001
Antisense inhibition of glycogen synthase kinase 3 alpha expression
ISIS PHARMACEUTICALS INC7 citations74
US6136604AOct 24, 2000
Antisense inhibition of methionine aminopeptidase 2 expression
ISIS PHARMACEUTICALS INC11 citations74
US6306655B1Oct 23, 2001
Antisense inhibition of C/EBP alpha expression
ISIS PHARMACEUTICALS INC12 citations73
US5672472ASep 30, 1997
Synthetic unrandomization of oligomer fragments
ISIS PHARMACEUTICALS INC12 citations73
US6268151B1Jul 31, 2001
Antisense modulation of macrophage migration inhibitory factor expression
ISIS PHARMACEUTICALS INC12 citations69
US6906186B1Jun 14, 2005
Antisense modulation of polo-like kinase expression
ISIS PHARMACEUTICALS INC5 citations63
US6716975B2Apr 6, 2004
Antisense modulation of EDG1 expression
ISIS PHARMACEUTICALS INC2 citations63
US6653133B1Nov 25, 2003
Antisense modulation of Fas mediated signaling
ISIS PHARMACEUTICALS INC2 citations63
US6503756B1Jan 7, 2003
Antisense modulation of syntaxin 4 interacting protein expression
ISIS PHARMACEUTICALS INC4 citations63
US6387699B1May 14, 2002
Antisense inhibition of A20 expression
ISIS PHARMACEUTICALS INC4 citations63
US6306606B1Oct 23, 2001
Antisense modulation of MP-1 expression
ISIS PHARMACEUTICALS INC4 citations63
US6165791ADec 26, 2000
Antisense inhibition of E2F transcription factor 3 expression
ISIS PHARMACEUTICALS INC3 citations61
US6492172B1Dec 10, 2002
Antisense modulation of GU protein expression
ISIS PHARMACEUTICALS INC0 citations52
US6475797B1Nov 5, 2002
Antisense modulation of SR-CYP expression
ISIS PHARMACEUTICALS INC1 citations52
US6465250B1Oct 15, 2002
Antisense modulation of protein phosphatase 2 catalytic subunit alpha expression
ISIS PHARMACEUTICALS INC1 citations52
US6458591B1Oct 1, 2002
Antisense modulation of phosphorylase kinase Alpha 2 expression
ISIS PHARMACEUTICALS INC0 citations52
US6426188B1Jul 30, 2002
Antisense modulation of phosphorylase kinase alpha 1 expression
ISIS PHARMACEUTICALS INC1 citations52
US6368856B1Apr 9, 2002
Antisense inhibition of Phosphorylase kinase beta expression
ISIS PHARMACEUTICALS INC1 citations52
US6255110B1Jul 3, 2001
Antisense modulation of ARA70 expression
ISIS PHARMACEUTICALS INC1 citations52
US6855700B2Feb 15, 2005
Antisense modulation of damage-specific DNA binding protein 1, p127 expression
ISIS PHARMACEUTICALS INC0 citations51
US6586245B2Jul 1, 2003
Antisense modulation of CD40 ligand expression
ISIS PHARMACEUTICALS INC0 citations40