Inventor
CONG LE
US26 patents
⚠️ This page may combine multiple inventors who share the name “CONG LE”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
BROAD INST INC
21 patentsUS8932814B2Jan 13, 2015
CRISPR-Cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
BROAD INST INC711 citations99
US8906616B2Dec 9, 2014
Engineering of systems, methods and optimized guide compositions for sequence manipulation
BROAD INST INC738 citations99
US8871445B2Oct 28, 2014
CRISPR-Cas component systems, methods and compositions for sequence manipulation
BROAD INST INC897 citations99
US8614092B2Dec 24, 2013
Nucleotide-specific recognition sequences for designer TAL effectors
BROAD INST INC92 citations99
US8507272B2Aug 13, 2013
Nucleotide-specific recognition sequences for designer TAL effectors
BROAD INST INC95 citations99
US10577630B2Mar 3, 2020
Delivery and use of the CRISPR-Cas systems, vectors and compositions for hepatic targeting and therapy
BROAD INST INC74 citations98
US8999641B2Apr 7, 2015
Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
BROAD INST INC709 citations98
US8993233B2Mar 31, 2015
Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
BROAD INST INC806 citations98
US8481309B2Jul 9, 2013
Nucleotide-specific recognition sequences for designer TAL effectors
BROAD INST INC68 citations98
US10946108B2Mar 16, 2021
Delivery, use and therapeutic applications of the CRISPR-Cas systems and compositions for targeting disorders and diseases using viral components
BROAD INST INC44 citations92
US11332719B2May 17, 2022
Recombinant virus and preparations thereof
BROAD INST INC14 citations84
US11578312B2Feb 14, 2023
Engineering and optimization of systems, methods, enzymes and guide scaffolds of CAS9 orthologs and variants for sequence manipulation
BROAD INST INC14 citations83
US11214797B2Jan 4, 2022
Assays for massively combinatorial perturbation profiling and cellular circuit reconstruction
BROAD INST INC11 citations81
US12018275B2Jun 25, 2024
Delivery and use of the CRISPR-CAS systems, vectors and compositions for hepatic targeting and therapy
BROAD INST INC2 citations73
US11407985B2Aug 9, 2022
Delivery, use and therapeutic applications of the CRISPR-Cas systems and compositions for genome editing
BROAD INST INC6 citations72
US11312937B2Apr 26, 2022
Nucleotide-specific recognition sequences for designer TAL effectors
BROAD INST INC0 citations63
US11186825B2Nov 30, 2021
Compositions and methods for evaluating and modulating immune responses by detecting and targeting POU2AF1
BROAD INST INC0 citations61
US11180730B2Nov 23, 2021
Compositions and methods for evaluating and modulating immune responses by detecting and targeting GATA3
BROAD INST INC0 citations61
US12168789B2Dec 17, 2024
Engineering and optimization of systems, methods, enzymes and guide scaffolds of CAS9 orthologs and variants for sequence manipulation
BROAD INST INC0 citations60
US11996168B2May 28, 2024
Systems and methods for determining relative abundances of biomolecules
BROAD INST INC0 citations50
US10801017B2Oct 13, 2020
Nucleotide-specific recognition sequences for designer TAL effectors
BROAD INST INC0 citations45