Inventor
RAN FEI
US20 patents
⚠️ This page may combine multiple inventors who share the name “RAN FEI”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
BROAD INST INC
19 patentsUS8906616B2Dec 9, 2014
Engineering of systems, methods and optimized guide compositions for sequence manipulation
BROAD INST INC738 citations99
US8895308B1Nov 25, 2014
Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation
BROAD INST INC706 citations99
US8889418B2Nov 18, 2014
Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation
BROAD INST INC663 citations99
US8865406B2Oct 21, 2014
Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation
BROAD INST INC826 citations99
US10577630B2Mar 3, 2020
Delivery and use of the CRISPR-Cas systems, vectors and compositions for hepatic targeting and therapy
BROAD INST INC74 citations98
US8993233B2Mar 31, 2015
Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
BROAD INST INC806 citations98
US10711285B2Jul 14, 2020
Optimized CRISPR-Cas double nickase systems, methods and compositions for sequence manipulation
BROAD INST INC15 citations93
US10946108B2Mar 16, 2021
Delivery, use and therapeutic applications of the CRISPR-Cas systems and compositions for targeting disorders and diseases using viral components
BROAD INST INC44 citations92
US10550372B2Feb 4, 2020
Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems
BROAD INST INC28 citations92
US12110490B2Oct 8, 2024
CRISPR enzymes and systems
BROAD INST INC7 citations85
US11597949B2Mar 7, 2023
Optimized CRISPR-Cas double nickase systems, methods and compositions for sequence manipulation
BROAD INST INC10 citations85
US11008588B2May 18, 2021
Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation
BROAD INST INC13 citations85
US11578312B2Feb 14, 2023
Engineering and optimization of systems, methods, enzymes and guide scaffolds of CAS9 orthologs and variants for sequence manipulation
BROAD INST INC14 citations83
US12018275B2Jun 25, 2024
Delivery and use of the CRISPR-CAS systems, vectors and compositions for hepatic targeting and therapy
BROAD INST INC2 citations73
US11597919B2Mar 7, 2023
Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems
BROAD INST INC2 citations71
US12553065B2Feb 17, 2026
Optimized CRISPR-CAS double nickase systems, methods and compositions for sequence manipulation
BROAD INST INC0 citations62
US12421506B2Sep 23, 2025
Engineering of systems, methods and optimized guide compositions with new architectures for sequence manipulation
BROAD INST INC0 citations62
US12258595B2Mar 25, 2025
Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems
BROAD INST INC0 citations60
US12168789B2Dec 17, 2024
Engineering and optimization of systems, methods, enzymes and guide scaffolds of CAS9 orthologs and variants for sequence manipulation
BROAD INST INC0 citations60