Inventor

LINDSLEY CRAIG W

US132 patents

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LINDSLEY CRAIG W

UNIV VANDERBILT

Antagonists of the muscarinic acetylcholine receptor M4

Fused heterocyclic compounds as selective BMP inhibitors

Fused heterocyclic compounds as selective BMP inhibitors

Substituted pyrazolo[3′,4′:4,5]thieno[2,3-C]pyridazin-3-amine analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4

Antagonists of the muscarinic acetylcholine receptor M4

Substituted 5-aminothieno[2,3-C]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4

Substituted thieno[2,3-C]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4

Substituted bicyclic heteroaryl carboxamide analogs as mGluR5 negative allosteric modulators

Substituted 5-aminothieno[2,3—C]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4

Substituted (1-(methylsulfonyl)azetidin-3-yl)(heterocycloalkyl)methanone analogs as antagonists of muscarinic acetylcholine M1 receptors

Bicyclic mGluR5 positive allosteric modulators and methods of making and using same

Indazole compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

Positive allosteric modulators of the muscarinic acetylcholine receptor M4

Benzoisoxazole-substituted compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

Substituted 1H-pyrazolo[3′,4′,4,5]thieno[2,3-b]pyridin-3-amine analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4

Compounds and methods useful for directing stem cell differentiation

Antagonists of the muscarinic acetylcholine receptor M4

Substituted octahydropyrrolo[3,4-b]pyrroles as antagonists of the muscarinic acetylcholine receptor M4

Substituted pyrimido[1,2-b]pyridazines as positive allosteric modulators of the muscarinic acetylcholine receptor M4

Antagonists of the muscarinic acetylcholine receptor M4

Antagonists of the muscarinic acetylcholine receptor M4

Antagonists of the muscarinic acetylcholine receptor M4

Positive allosteric modulators of the muscarinic acetylcholine receptor M4

Substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M1

Substituted 4-(1H-pyrazol-4-yl)benzyl analogues as positive allosteric modulators of mAChR M1 receptors

Antagonists of the muscarinic acetylcholine receptor M4

Negative allosteric modulators of metabotropic glutamate receptor 2

Substituted quinazolin-4(3H)-ones, pyrido[3,4-d]pyrimidin-4(3H)-ones, pyrido[3,2-d]pyrimidin-4(3H)-ones and pyrido[2,3-d]pyrimidin-4(3H)-ones as positive allosteric modulators of muscarinic acetycholine receptor M1

CONN P JEFFREY

mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

Benzisoxazoles and azabenzisoxazoles as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

Substituted dioxopiperidines and dioxopyrrolidines as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

Substituted 1,1,3,1-tetraoxidobenzo[D][1,3,2]dithiazoles as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

Heterocyclic sulfone mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

Pyrazolopyridine, pyrarolopyrazine, pyrazolopyrimidine, pyrazolothiophene and pyrazolothiazole compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

Pyrazolopyridine, pyrazolopyrazine, pyrazolopyrimidine, pyrazolothiophene and pyrazolothiazole compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

Aryl and heteroaryl sulfones as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

Substituted benzamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same

MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

Substituted heteroarylamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same

Substituted phenylamine carboxamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same

Substituted heteroarylamine carboxamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same

6-alkyl-N-(pyridin-2-yl)-4-aryloxypicolinamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same

Bicyclic triazole and pyrazole lactams as allosteric modulators of mGluR5 receptors

MERCK & CO INC

Inhibitors of Akt activity

Inhibitors of Akt activity

Inhibitors of Akt activity

Inhibitors of Akt activity

Inhibitors of Akt activity

Inhibitors of Akt activity

Inhibitors of Akt activity