Inventor
PANTOLIANO MICHAEL W
US24 patents
⚠️ This page may combine multiple inventors who share the name “PANTOLIANO MICHAEL W”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
DIMENSIONAL PHARM INC
14 patentsUS6569631B1May 27, 2003
Microplate thermal shift assay for ligand development using 5-(4″dimethylaminophenyl)-2-(4′-phenyl)oxazole derivative fluorescent dyes
DIMENSIONAL PHARM INC270 citations98
US6268158B1Jul 31, 2001
Method for determining conditions that facilitate protein crystallization
DIMENSIONAL PHARM INC87 citations98
US6036920AMar 14, 2000
Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization
DIMENSIONAL PHARM INC153 citations98
US6020141AFeb 1, 2000
Microplate thermal shift assay for ligand development and multi-variable protein chemistry optimization
DIMENSIONAL PHARM INC141 citations98
US6214293B1Apr 10, 2001
Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization
DIMENSIONAL PHARM INC70 citations97
US6303322B1Oct 16, 2001
Method for identifying lead compounds
DIMENSIONAL PHARM INC50 citations96
US6268218B1Jul 31, 2001
Method for sensing and processing fluorescence data from multiple samples
DIMENSIONAL PHARM INC37 citations96
US6291192B1Sep 18, 2001
Method for identifying conditions that facilitate recombinant protein folding
DIMENSIONAL PHARM INC28 citations95
US6232085B1May 15, 2001
Method for determining conditions that stabilize proteins
DIMENSIONAL PHARM INC29 citations95
US6274712B1Aug 14, 2001
Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamute 89, aspartate 101 or leucine 137
DIMENSIONAL PHARM INC48 citations94
US6291191B1Sep 18, 2001
Microplate thermal shift assay for ligand development and multi-variable protein chemistry optimization
DIMENSIONAL PHARM INC19 citations92
US6737404B2May 18, 2004
Methods of using analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, aspartate 101 or leucine 137
DIMENSIONAL PHARM INC10 citations72
US6767722B1Jul 27, 2004
Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, Aspartate 101 or Leucine 137
DIMENSIONAL PHARM INC1 citations61
US7138374B2Nov 21, 2006
Methods of using analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, asparate 101 or leucine 137
DIMENSIONAL PHARM INC0 citations51
GENEX CORP
5 patentsUS4908773AMar 13, 1990
Computer designed stabilized proteins and method for producing same
GENEX CORP147 citations98
US4990452AFeb 5, 1991
Combining mutations for stabilization of subtilisin
GENEX CORP57 citations96
US4853871AAug 1, 1989
Computer-based method for designing stablized proteins
GENEX CORP123 citations96
US4980288ADec 25, 1990
Subtilisin with increased thermal stability
GENEX CORP100 citations94
US5116741AMay 26, 1992
Biosynthetic uses of thermostable proteases
GENEX CORP44 citations88