Inventor
ZUTTER ULRICH
CH14 patents
Patents
14 patentsUS5399720AMar 21, 1995
Production of oxetanones
HOFFMANN LA ROCHE66 citations94
US5245056ASep 14, 1993
Production of oxetanones
HOFFMANN LA ROCHE44 citations91
US7312343B2Dec 25, 2007
Synthesis of α-amino-β-alkoxy-carboxylic acid esters
HOFFMANN LA ROCHE7 citations73
US5902882AMay 11, 1999
Assymetric synthesis of azepines
HOFFMANN LA ROCHE10 citations70
US6277997B1Aug 21, 2001
Process for the preparation of chiral lactones
HOFFMANN LA ROCHE2 citations62
US7956201B2Jun 7, 2011
Process for the preparation of (S)-4-fluoromethyl-dihydro-furan-2-one
HOFFMANN LA ROCHE3 citations61
US5481008AJan 2, 1996
Process for the preparation of optically active compounds
HOFFMANN LA ROCHE5 citations61
US7619101B2Nov 17, 2009
Process for the preparation of (S)-4-fluoromethyl-dihydro-furan-2-one useful in the preparation of the DPP-IV inhibitor (S)-1 ((2S,3S,11bS)-2-amino-9,10-dimethoxy-1,3,4,6,7, 11b-hexahydro-2H-pyrido[2,1-a] isoquinolin-3-yl)-4-fluoromethyl-pyrrolidin-2-one
HOFFMANN LA ROCHE4 citations60
US9562009B2Feb 7, 2017
Process to manufacture N-[(3S)-1-[4-[(3-fluorophenyl)methoxy]phenyl]-5-oxo-pyrrolidin-3-yl]acetamide
HOFFMANN LA ROCHE0 citations51
US6222039B1Apr 24, 2001
Process for the preparation of chiral lactones
HOFFMANN LA ROCHE1 citations51
US6914140B1Jul 5, 2005
Asymmetric synthesis process
HOFFMANN LA ROCHE0 citations49
US6069245AMay 30, 2000
Asymmetric synthesis of azepines
HOFFMANN LA ROCHE0 citations49
US6518048B2Feb 11, 2003
Stereo-specific synthesis of shimikic acid derivatives with improved efficiency
HOFFMANN LA ROCHE0 citations41
US8796471B2Aug 5, 2014
Process for the preparation of proline derivatives
HOFFMANN LA ROCHE0 citations36