Inventor

ECONOMIDES ARIS N

US49 patents

⚠️ This page may combine multiple inventors who share the name “ECONOMIDES ARIS N”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

ECONOMIDES ARIS N

REGENERON PHARMA

Methods of modifying eukaryotic cells

Genome mutation by intron insertion into an embryonic stem cell genome

CNTF and IL-6 antagonists

Methods of making a nucleic acid encoding a human variable region

Methods of producing hybrid antibodies

Genetically modified mice that produce hybrid antibodies

Methods of producing hybrid antibodies

Method for genetically modifying isolated non-human mammalian cell by homologous recombination

Method for targeting transcriptionally active loci

Genetically modified mouse with an inducible Acvr1 gene with a mutant R206H exon 5 that has ectopic bone formation

Morphogenic proteins

Mice that produce hybrid antibodies

Genetically modified mice that produce hybrid antibodies

Methods of making a nucleic acid encoding a human variable region

Mice that produce hybrid antibodies

Mice that produce hybrid antibodies

Mouse embryonic stem cells comprising a hybrid heavy chain immunoglobulin locus

Methods of modifying eukaryotic cells

Methods of modifying eukaryotic cells

Methods of producing hybrid antibodies

Multispecific antigen-binding molecules binding to a target and an internalizing effector protein that is CD63 and uses thereof

Nucleic acid construct for making a genetically modified rodent with an inducible ACVR1 mutation that causes ectopic bone formation

Human antibodies to GREM1

Mice that produce hybrid antibodies

Compositions and methods for modifying cells

Conditional rodent Acvr1 mutant gene

Method for making a genetically modified mouse with an inducible ACVR1 mutation that causes ectopic bone formation

Rodent embryonic stem cell with conditional ACVR1 mutant alleles

Genetically modified rodent with an inducible ACVR1 mutation in exon 7 that causes ectopic bone formation

Treatment of fibrodysplasia ossificans progressiva

Multifunctional alleles

Therapeutic method for treating bone formation diseases

Methods of modifying genes in eukaryotic cells

Fibrillin-1 mutations for modeling neonatal progeroid syndrome with congenital lipodystrophy

Genetically modified mouse with an inducible ACVR1 gene with a mutant R206H exon 5 that has ectopic bone formation

Fibrillin-1 mutations for modeling neonatal progeroid syndrome with congenital lipodystrophy

Human antibodies to GREM1

Methods for modifying a genome

Nucleic acids comprising a modified rodent activin a receptor type 1 (Acvr1) gene

Multifunctional alleles

DCR-5 bone affecting ligand

DCR5, a BMP-binding protein, and applications thereof

Morphogenic protein

Anti-ACVR1 antibodies and uses thereof

MURPHY ANDREW J

Hybrid antibodies comprising human variable regions and mouse constant regions produced in a genetically modified mouse

Methods of producing hybrid antibodies

ECONOMIDES ARIS N

Method for genetically modifying mouse embryonic stem cell by homologous recombination

Method for detecting the replacement of an endogenous allele with a modified allele by homologous recombination in a mouse ES cell

MARTIN JOEL H

Human antibodies to human RANKL, encoding nucleic acids and methods of treatment