Inventor
BIGNER DARELL
US28 patents
⚠️ This page may combine multiple inventors who share the name “BIGNER DARELL”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
UNIV JOHNS HOPKINS
11 patentsUS5212290AMay 18, 1993
Antibodies specific for type II mutant EGTR
UNIV JOHNS HOPKINS318 citations98
US6455498B1Sep 24, 2002
Structural alterations of the EGF receptor genes in human tumors
UNIV JOHNS HOPKINS46 citations96
US6127126AOct 3, 2000
Method for diagnosing glioma associated with structural alterations of the EGF receptor gene in human tumors
UNIV JOHNS HOPKINS57 citations96
US5814317ASep 29, 1998
Structural alterations of the EGF receptor gene in human gliomas
UNIV JOHNS HOPKINS39 citations96
US5710010AJan 20, 1998
Assays for the presence of a mutant EGF receptor
UNIV JOHNS HOPKINS42 citations96
US5401828AMar 28, 1995
Structural alterations of the EGF receptor gene in human gliomas
UNIV JOHNS HOPKINS62 citations96
US10704108B2Jul 7, 2020
Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma
UNIV JOHNS HOPKINS22 citations93
US9353418B2May 31, 2016
Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma
UNIV JOHNS HOPKINS13 citations92
US10837064B2Nov 17, 2020
Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma
UNIV JOHNS HOPKINS9 citations83
US11254988B2Feb 22, 2022
Somatic mutations in ATRX in brain cancer
UNIV JOHNS HOPKINS0 citations60
US10619217B2Apr 14, 2020
Oligodendroglioma drive genes
UNIV JOHNS HOPKINS0 citations50
UNIV DUKE
8 patentsUS11331343B2May 17, 2022
Compositions and methods for activating antigen presenting cells with chimeric poliovirus
UNIV DUKE1 citations61
US12514927B2Jan 6, 2026
Immunotherapy with combination therapy comprising an immunotoxin
UNIV DUKE0 citations60
US11428691B2Aug 30, 2022
Methods for predicting tumor response to immunotherapy
UNIV DUKE0 citations59
US9492564B2Nov 15, 2016
Dual specific immunotoxin for brain tumor therapy
UNIV DUKE2 citations58
US11065332B2Jul 20, 2021
Combination therapy of immunotoxin and checkpoint inhibitor
UNIV DUKE1 citations57
US10052382B2Aug 21, 2018
Methods for using antibodies for 3′ iso-LM1 and 3′, 6′-iso-LD1tumor gangliosides
UNIV DUKE0 citations49
US9676858B2Jun 13, 2017
Human bispecific EGFRvIII antibody and CD3 engaging molecules
UNIV DUKE0 citations49
US10633711B2Apr 28, 2020
Methods for rapid and sensitive detection of hotspot mutations
UNIV DUKE0 citations44
VOGELSTEIN BERT
3 patentsUS8685660B2Apr 1, 2014
Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma
VOGELSTEIN BERT21 citations91
US9873917B2Jan 23, 2018
Oligodendroglioma drive genes
VOGELSTEIN BERT2 citations71
US9695479B2Jul 4, 2017
Medulloblastoma genes as targets for diagnosis and therapeutics
VOGELSTEIN BERT2 citations71
YAN HAI
3 patentsUS9982306B2May 29, 2018
Somatic mutations in ATRX in brain cancer
YAN HAI0 citations49
US9695400B2Jul 4, 2017
Homozygous and heterozygous IDH1 gene-defective human astrocytoma cell lines
YAN HAI0 citations45
US9074221B2Jul 7, 2015
Homozygous and heterozygous IDH1 gene-defective cell lines derived from human colorectal cells
YAN HAI0 citations45