Inventor · disambiguated record
Klaus Schiene
Also filed as: SCHIENE KLAUS
56 granted patents·56 pending applications·160 citations·filing 2003–2023
98Inventor score
Top patents by PatentIndex Score
112 records- 0190US8642623B2Vanilloid receptor ligand compounds, pharmaceutical compositions containing them, a method of producing them and the use thereof to treat pain and various other conditionsFRANK ROBERT·Filed 2012·Granted Feb 4, 2014·14 cites·18 claims
- 0289US7625900B2Sutstituted tetrahydropyrrolopyrazine compounds and the use thereof in the treatment and/or inhibition of painGRUENENTHAL GMBH·Filed 2007·Granted Dec 1, 2009·12 cites·18 claims
- 0387US8252816B2Vanilloid receptor ligand compounds, pharmaceutical compositions containing them, a method of producing them and the use thereof to treat pain and various other conditionsFRANK ROBERT·Filed 2008·Granted Aug 28, 2012·10 cites·18 claims
- 0487US8084484B2Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditionsFRANK ROBERT·Filed 2008·Granted Dec 27, 2011·10 cites·33 claims
- 0587US8017772B2Substituted tetrahydropyrrolopyrazine compounds and the use thereof in the treatment and/or inhibition of painGRUENENTHAL GMBH·Filed 2009·Granted Sep 13, 2011·9 cites·13 claims
- 0687US7879858B2Substituted tetrahydropyrrolopyrazine compounds and the use thereof in pharmaceutical compositionsGRUENENTHAL GMBH·Filed 2009·Granted Feb 1, 2011·9 cites·2 claims
- 0786US7786160B2Combination of selected analgesics and COX-II inhibitorsGRUENENTHAL GMBH·Filed 2005·Granted Aug 31, 2010·6 cites·11 claims
- 0885US7300939B2Substituted 1-propiolylpiperazine compounds, their preparation and useGRUENENTHAL GMBH·Filed 2007·Granted Nov 27, 2007·9 cites·46 claims
- 0983US7879991B2CGRP binding nucleic acidsNOXXON PHARMA AG·Filed 2003·Granted Feb 1, 2011·21 cites·25 claims
- 1083US2023174540A13-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane DerivativesGRUENENTHAL GMBH·Filed 2023·Application pending·0 cites
- 1182US10829480B23-((hetero-)aryl)-alkyl-8-amino-2-oxo-l,3-diaza-spiro-[4.5]-decane derivativesGRUENENTHAL GMBH·Filed 2019·Granted Nov 10, 2020·1 cites·27 claims
- 1282US9320729B2Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivativeGRUENENTHAL GMBH·Filed 2013·Granted Apr 26, 2016·5 cites·23 claims
- 1382US7420056B2Substituted bicyclic imidazo-3-ylamine compoundsGRUENENTHAL GMBH·Filed 2007·Granted Sep 2, 2008·7 cites·57 claims
- 1482US2023174520A13-((Hetero-)Aryl)-Alkyl-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane DerivativesGRUENENTHAL GMBH·Filed 2023·Application pending·0 cites
- 1580US8334315B2Substituted aromatic carboxamide and urea derivatives as vanilloid receptor ligandsFRANK ROBERT·Filed 2010·Granted Dec 18, 2012·6 cites·14 claims
- 1679US7893069B2Substituted imidazo[2,1-b]thiazole compounds and uses thereofGRUENENTHAL GMBH·Filed 2008·Granted Feb 22, 2011·4 cites·30 claims
- 1777US11311504B2Pharmaceutical composition comprising (1R,4R)-6′- fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro [cyclohexane-1,1′-pyrano- [3,4,b ]indol] -4-amine and paracetamol or propacetamolGRUENENTHAL GMBH·Filed 2019·Granted Apr 26, 2022·1 cites·17 claims
- 1877US8642775B2Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditionsFRANK ROBERT·Filed 2008·Granted Feb 4, 2014·3 cites·28 claims
- 1976US8420691B2Combination of selected analgesics and COX-II inhibitorsSCHIENE KLAUS·Filed 2010·Granted Apr 16, 2013·2 cites·9 claims
- 2076US7109214B2Substituted cyclopentene compoundsGRUENENTHAL CHEMIE·Filed 2004·Granted Sep 19, 2006·10 cites·51 claims
- 2175US8710233B2Vanilloid receptor ligands and use thereof for the production of pharmaceutical preparationsLEE JEEWOO·Filed 2006·Granted Apr 29, 2014·5 cites·22 claims
- 2275US8592471B2Substituted phenylureas and phenylamides as vanilloid receptor ligandsFRANK ROBERT·Filed 2010·Granted Nov 26, 2013·3 cites·11 claims
- 2375US2021212967A1Treatment of Irritable Bowel SyndromeGRUENENTHAL GMBH·Filed 2021·Application pending·0 cites
- 2474US8912226B2Pharmaceutical composition comprising (1r,4r) -6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a NSARGRUENENTHAL GMBH·Filed 2013·Granted Dec 16, 2014·2 cites·18 claims
- 2574US8084470B2Substituted nicotinamide compounds and uses thereofMERLA BEATRIX·Filed 2008·Granted Dec 27, 2011·2 cites·18 claims
- 2674US7871999B2Substituted thiazoles and their use for producing drugsGRUENENTHAL GMBH·Filed 2008·Granted Jan 18, 2011·2 cites·30 claims
- 2774US2021179627A13-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane DerivativesGRUENENTHAL GMBH·Filed 2021·Application pending·0 cites
- 2873US2021179592A13-((hetero-)aryl)-alkyl-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivativesGRUENENTHAL GMBH·Filed 2021·Application pending·0 cites
- 2972US10076510B2Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivativeGRUENENTHAL GMBH·Filed 2016·Granted Sep 18, 2018·1 cites·19 claims
- 3072US8618177B2Method of treating pain caused by inflammationSCHIENE KLAUS·Filed 2010·Granted Dec 31, 2013·1 cites·7 claims
- 3172US8367700B2Substituted 4-(1.2,3,4-tetrahydroisoquinolin-2-yl)-4-oxobutyric acid amide as KCNQ2/3 modulatorsGRUENENTHAL GMBH·Filed 2009·Granted Feb 5, 2013·1 cites·13 claims
- 3272US2020399280A13-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane DerivativesGRUENENTHAL GMBH·Filed 2020·Application pending·0 cites
- 3371US2020399252A13-((hetero-)aryl)-alkyl-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivativesGRUENENTHAL CHEMIE·Filed 2020·Application pending·0 cites
- 3471US2018200205A1Treatment of Irritable Bowel SyndromeGRUENENTHAL GMBH·Filed 2018·Application pending·0 cites
- 3570US10807989B23-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivativesGRUENENTHAL GMBH·Filed 2019·Granted Oct 20, 2020·0 cites·31 claims
- 3669US10398657B2Method of inhibiting chronification of painGRUENENTHAL GMBH·Filed 2016·Granted Sep 3, 2019·1 cites·17 claims
- 3769US9308196B2Pharmaceutical composition comprising (1 r,4r) -6'-fluoro-N ,N-dimethyl-4-phenyl-4',9'-d ihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicamGRUENENTHAL GMBH·Filed 2013·Granted Apr 12, 2016·1 cites·9 claims
- 3869US9120756B2Substituted phenylureas and phenylamides as vanilloid receptor ligandsGRUENENTHAL GMBH·Filed 2013·Granted Sep 1, 2015·1 cites·19 claims
- 3969US8846765B2Pharmaceutical combinationSCHIENE KLAUS·Filed 2011·Granted Sep 30, 2014·1 cites·12 claims
- 4068US2017216226A1Treatment of Irritable Bowel SyndromeGRUENENTHAL GMBH·Filed 2017·Application pending·0 cites
- 4167US10813890B2Pharmaceutical combinationGRUENENTHAL GMBH·Filed 2017·Granted Oct 27, 2020·0 cites·16 claims
- 4267US2019106430A13-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivativesGRUENENTHAL GMBH·Filed 2018·Application pending·0 cites
- 4367US2019133971A1Pharmaceutical CombinationGRUENENTHAL GMBH·Filed 2019·Application pending·0 cites
- 4467US2013116334A1Treatment of Irritable Bowel SyndromeGRUENENTHAL GMBH·Filed 2012·Application pending·0 cites
- 4565US2007254960A1Pharmaceutical combinationGRUENENTHAL GMBH·Filed 2007·Application pending·0 cites
- 4665US2018282341A13-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivativesGRUENENTHAL GMBH·Filed 2018·Application pending·0 cites
- 4764US2018327392A13-((hetero-)aryl)-alkyl-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivativesGRUENENTHAL GMBH·Filed 2018·Application pending·0 cites
- 4863US2012004317A1Tapentadol for use in the treatment of irritable bowel syndromeSCHIENE KLAUS·Filed 2011·Application pending·0 cites
- 4963US2017197971A13-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane DerivativesGRUENENTHAL GMBH·Filed 2017·Application pending·0 cites
- 5062US10471079B2Combination of selected analgesics and COX-II inhibitorsGRUENENTHAL GMBH·Filed 2016·Granted Nov 12, 2019·0 cites·26 claims
Showing the top 50 of 112 patent records by PatentIndex Score.
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