Inventor · disambiguated record
Marc K. Hellerstein
Also filed as: HELLERSTEIN MARC · HELLERSTEIN MARC K
34 granted patents·21 pending applications·850 citations·filing 1992–2018
98Inventor score
Top patents by PatentIndex Score
55 records- 0197US8005623B2Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activityUNIV CALIFORNIA·Filed 2005·Granted Aug 23, 2011·36 cites·17 claims
- 0295US8129335B2Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome using mass spectrometryHELLERSTEIN MARC K·Filed 2009·Granted Mar 6, 2012·23 cites·11 claims
- 0395US8021644B2Methods for measuring rates of reverse cholesterol transport in vivo, as an index of anti-atherogenesisUNIV CALIFORNIA·Filed 2007·Granted Sep 20, 2011·19 cites·4 claims
- 0495US7410633B2Measurement of protein synthesis rates in humans and experimental systems by use of isotopically labeled waterUNIV CALIFORNIA·Filed 2005·Granted Aug 12, 2008·22 cites·17 claims
- 0595US6808875B2Methods for screening cellular proliferation using isotope labelsUNIV CALIFORNIA·Filed 2002·Granted Oct 26, 2004·55 cites·16 claims
- 0694US8401800B2Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activityHELLERSTEIN MARC K·Filed 2011·Granted Mar 19, 2013·10 cites·18 claims
- 0794US7357913B2Methods for detecting, prognosing, or monitoring a disorder by comparing relative flux rates of two or more biological molecules in vivoUNIV CALIFORNIA·Filed 2006·Granted Apr 15, 2008·22 cites·42 claims
- 0894US7022834B2Isotopically labelled DNAUNIV CALIFORNIA·Filed 2004·Granted Apr 4, 2006·40 cites·33 claims
- 0994US5338686AMethod for measuring in vivo synthesis of biopolymersHELLERSTEIN MARC K·Filed 1992·Granted Aug 16, 1994·90 cites·9 claims
- 1093US8969287B2Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome using mass spectrometryUNIV CALIFORNIA·Filed 2013·Granted Mar 3, 2015·8 cites·13 claims
- 1193US8849581B2Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activityUNIV CALIFORNIA·Filed 2013·Granted Sep 30, 2014·7 cites·19 claims
- 1293US7910323B2Methods for identifying the effect of a drug agent on the metabolism of sugars and fats in an individualUNIV CALIFORNIA·Filed 2009·Granted Mar 22, 2011·20 cites·19 claims
- 1393US7449171B2Measurement of biosynthesis and breakdown rates of biological molecules that are inaccessible or not easily accessible to direct sampling, non-invasively, by label incorporation into metabolic derivatives and catabolic productsUNIV CALIFORNIA·Filed 2003·Granted Nov 11, 2008·40 cites·42 claims
- 1493US7262020B2Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocolUNIV CALIFORNIA·Filed 2004·Granted Aug 28, 2007·48 cites·41 claims
- 1593US7001587B2Measurement of protein synthesis rates in humans and experimental systems by use of isotopically labeled waterUNIV CALIFORNIA·Filed 2002·Granted Feb 21, 2006·44 cites·14 claims
- 1692US9043159B2Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activityUNIV CALIFORNIA·Filed 2014·Granted May 26, 2015·6 cites·19 claims
- 1792US9037417B2Molecular flux rates through critical pathways measured by stable isotope labeling In Vivo, as biomarkers of drug action and disease activityUNIV CALIFORNIA·Filed 2014·Granted May 19, 2015·6 cites·19 claims
- 1892US8663602B2Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systemsHELLERSTEIN MARC K·Filed 2011·Granted Mar 4, 2014·9 cites·14 claims
- 1991US7504233B2Methods for determining the metabolism of sugars and fats in an individualUNIV CALIFORNIA·Filed 2003·Granted Mar 17, 2009·37 cites·25 claims
- 2091US6461806B1Methods for measuring cellular proliferation and destruction rates in vitro and in vivoUNIV CALIFORNIA·Filed 1999·Granted Oct 8, 2002·65 cites·17 claims
- 2189US8741589B2Monitoring two dimensions of diabetes pathogenesisHELLERSTEIN MARC K·Filed 2006·Granted Jun 3, 2014·6 cites·8 claims
- 2289US8481478B2Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome using mass spectrometryHELLERSTEIN MARC K·Filed 2012·Granted Jul 9, 2013·13 cites·18 claims
- 2389US7255850B2Methods for measuring rates of reserve cholesterol transport in vivo, as an index of anti-atherogenesisUNIV CALIFORNIA·Filed 2003·Granted Aug 14, 2007·23 cites·21 claims
- 2488US5910403AMethods for measuring cellular proliferation and destruction rates in vitro and in vivoUNIV CALIFORNIA·Filed 1997·Granted Jun 8, 1999·83 cites·16 claims
- 2587US8084016B2Measurement of biosynthesis and breakdown rates of biological molecules that are inaccessible or not easily accessible to direct sampling, non-invasively, by label incorporation into metabolic derivatives and catabolitic productsHELLERSTEIN MARC K·Filed 2008·Granted Dec 27, 2011·14 cites·39 claims
- 2687US6010846AMethods for measuring cellular proliferation and destruction rates in vitro and in vivoUNIV CALIFORNIA·Filed 1998·Granted Jan 4, 2000·74 cites·24 claims
- 2786US9737260B2Methods for determining total body skeletal muscle massGLAXOSMITHKLINE LLC·Filed 2016·Granted Aug 22, 2017·2 cites·11 claims
- 2886US7307059B2Measurement of protein synthesis rates in humans and experimental systems by use of isotopically labeled waterUNIV CALIFORNIA·Filed 2004·Granted Dec 11, 2007·21 cites·20 claims
- 2980US9134319B2Method for replacing biomarkers of protein kinetics from tissue samples by biomarkers of protein kinetics from body fluids after isotopic labeling in vivoUNIV CALIFORNIA·Filed 2014·Granted Sep 15, 2015·6 cites·26 claims
- 3071US10466253B2Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activityUNIV CALIFORNIA·Filed 2017·Granted Nov 5, 2019·0 cites·20 claims
- 3169US2019029591A1Methods for determining total body skeletal muscle massGLAXOSMITHKLINE LLC·Filed 2018·Application pending·0 cites
- 3267US9778268B2Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activityUNIV CALIFORNIA·Filed 2014·Granted Oct 3, 2017·0 cites·19 claims
- 3367US9720002B2Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activityUNIV CALIFORNIA·Filed 2014·Granted Aug 1, 2017·0 cites·19 claims
- 3466US2017367648A1Methods for determining total body skeletal muscle massGLAXOSMITHKLINE LLC·Filed 2017·Application pending·0 cites
- 3562US2015233938A1Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome using mass spectrometryUNIV CALIFORNIA·Filed 2015·Application pending·0 cites
- 3662US2014162900A1Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systemsUNIV CALIFORNIA·Filed 2014·Application pending·0 cites
- 3757US10386371B2Metabolic flux measurement, imaging and microscopyBOWEN BENJAMIN P·Filed 2012·Granted Aug 20, 2019·1 cites·18 claims
- 3855US2005202406A1Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systemsUNIV CALIFORNIA·Filed 2004·Application pending·0 cites
- 3955US2006251576A1Methods for measuring cholesterol metabolism and transportUNIV CALIFORNIA·Filed 2006·Application pending·0 cites
- 4055US2007248540A1Biochemical methods for measuring metabolic fitness of tissues or whole organismsUNIV CALIFORNIA·Filed 2007·Application pending·0 cites
- 4155US2006008796A1Methods for screening cellular proliferation using isotope labelsUNIV CALIFORNIA·Filed 2005·Application pending·0 cites
- 4254US2004081994A1Biochemical methods for measuring metabolic fitness of tissues or whole organismsFiled 2003·Application pending·0 cites
- 4351US2005238577A1Isolation of epithelial cells or their biochemical contents from excreta after in vivo isotopic labelingUNIV CALIFORNIA·Filed 2005·Application pending·0 cites
- 4449US2016139154A1Methods for determining total body skeletal muscle massUNIV CALIFORNIA·Filed 2014·Application pending·0 cites
- 4547US2005255509A1In vivo measurement of the relative fluxes through ribonucleotide reductase vs. deoxyribonucleoside pathways using isotopesKINEMED INC·Filed 2005·Application pending·0 cites
- 4646US2003224420A1Method for isolating and measuring proliferation of long-term label retaining cells and stem cellsFiled 2003·Application pending·0 cites
- 4745US8883847B2Compositions and methods of treatment using modulators of motoneuron diseasesHELLERSTEIN MARC K·Filed 2007·Granted Nov 11, 2014·0 cites·8 claims
- 4844US2005201937A1Temporal or spatial characterization of biosynthetic events in living organisms by isotopic fingerprinting under conditions of imposed isotopic gradientsUNIV CALIFORNIA·Filed 2005·Application pending·0 cites
- 4943US2020232995A1Measurement of protein molecular flux rates by quantifying isotopologue abundances in immonium ion using high resolution mass spectrometryKINEMED INC·Filed 2016·Application pending·0 cites
- 5042US2018259531A1Measurement of molecular flux rates by quantifying isotopologue abundances using high resolution mass spectrometryKINEMED INC·Filed 2016·Application pending·0 cites
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Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →