Inventor · disambiguated record

Mariusz Krawiec

Also filed as: KRAWIEC MARIUSZ

31 granted patents·17 pending applications·1,564 citations·filing 2006–2022

98Inventor score

Technology areasA61P A61K C07D C07B G01N

Files withVERTEX PHARMA37 KESHAVARZ-SHOKRI ALI3 HURTER PATRICIA2 SHANNON DEAN2 ZHANG BEILI2

Top patents by PatentIndex Score

48 records

0199US9840499B2Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acidVERTEX PHARMA·Filed 2016·Granted Dec 12, 2017·41 cites·1 claims
0299US9434717B2Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acidVERTEX PHARMA·Filed 2015·Granted Sep 6, 2016·53 cites·5 claims
0399US8846718B2Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxo1-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acidVERTEX PHARMA·Filed 2013·Granted Sep 30, 2014·77 cites·23 claims
0498US10081621B2Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamideVERTEX PHARMA·Filed 2015·Granted Sep 25, 2018·29 cites·22 claims
0598US9670163B2Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamideVERTEX PHARMA·Filed 2015·Granted Jun 6, 2017·44 cites·8 claims
0698US9150552B2Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acidVERTEX PHARMA·Filed 2014·Granted Oct 6, 2015·58 cites·22 claims
0798US9139530B2Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamideVERTEX PHARMA·Filed 2014·Granted Sep 22, 2015·64 cites·28 claims
0898US9051303B2Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxol-5-YL)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan-2-YL)-1H-indol-5-YL)-cyclopropanecarboxamideVERTEX PHARMA·Filed 2014·Granted Jun 9, 2015·59 cites·25 claims
0998US8969574B2Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acidVERTEX PHARMA·Filed 2014·Granted Mar 3, 2015·61 cites·7 claims
1098US8802868B2Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-CyclopropanecarboxamideVERTEX PHARMA·Filed 2012·Granted Aug 12, 2014·68 cites·40 claims
1198US8742122B2Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acidVERTEX PHARMA·Filed 2013·Granted Jun 3, 2014·67 cites·7 claims
1298US8653103B2Solid forms of 3-(6-(1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acidKESHAVARZ-SHOKRI ALI·Filed 2012·Granted Feb 18, 2014·79 cites·1 claims
1398US8507687B2Solid forms of 3-(6-(1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acidKESHAVARZ-SHOKRI ALI·Filed 2011·Granted Aug 13, 2013·83 cites·5 claims
1498US8507534B2Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acidKESHAVARZ-SHOKRI ALI·Filed 2008·Granted Aug 13, 2013·101 cites·23 claims
1597US11578062B2Solid forms of (R)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamideVERTEX PHARMA·Filed 2020·Granted Feb 14, 2023·4 cites·19 claims
1697US10906891B2Solid forms of (R)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamideVERTEX PHARMA·Filed 2018·Granted Feb 2, 2021·13 cites·14 claims
1797US10597384B2Solid forms of 3-(6-(1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acidVERTEX PHARMA·Filed 2017·Granted Mar 24, 2020·17 cites·4 claims
1897US10537565B2Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamideVERTEX PHARMA·Filed 2018·Granted Jan 21, 2020·24 cites·26 claims
1997US9931334B2Solid forms of N[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamideVERTEX PHARMA·Filed 2017·Granted Apr 3, 2018·35 cites·17 claims
2097US8741922B2Solid forms of N-(4-(7-azabicyclo[2.2,1]heptan-7-yl)-2-trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamideVERTEX PHARMA·Filed 2013·Granted Jun 3, 2014·68 cites·9 claims
2197US8436014B2Solid forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluorormethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihyroquinoline-3-carboxamideZHANG BEILI·Filed 2009·Granted May 7, 2013·87 cites·13 claims
2296US9314455B2Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acidVERTEX PHAMRACEUTICALS INC·Filed 2015·Granted Apr 19, 2016·51 cites·37 claims
2396US8785476B2Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamideVERTEX PHARMA·Filed 2012·Granted Jul 22, 2014·72 cites·9 claims
2496US8410274B2Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamideHURTER PATRICIA·Filed 2012·Granted Apr 2, 2013·109 cites·22 claims
2596US8389727B2Solid forms of N-(4-(7-Azabicyclo[2.2.1]Heptan-7-yl)-2-Trifluoromethyl)Phenyl)-4-Oxo-5-(Trifluoromethyl)-1,4-Dihydroquinoline-3-CarboxamideZHANG BEILI·Filed 2010·Granted Mar 5, 2013·85 cites·53 claims
2694US8471029B2Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamideAREKAR SNEHA G·Filed 2011·Granted Jun 25, 2013·85 cites·15 claims
2792US11291662B2Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamideVERTEX PHARMA·Filed 2019·Granted Apr 5, 2022·5 cites·4 claims
2887US8481552B2Solid forms of gyrase inhibitor (R)-1-ethyl-3-[5-[2-(1-hydroxy-1-methyl-ethyl)pyrimidin-5-YL]-7-(tetrahydrofuran-2-yl)-1H-benzimidazol-2-YL]ureaSHANNON DEAN·Filed 2012·Granted Jul 9, 2013·12 cites·22 claims
2987US8476281B2Solid forms of gyrase inhibitor (R)-1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl)pyrimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1H-benzimidazol-2-yl]ureaSHANNON DEAN·Filed 2012·Granted Jul 2, 2013·12 cites·23 claims
3084US2023263794A1Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamideVERTEX PHARMA·Filed 2022·Application pending·0 cites
3183US12065432B2Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acidVERTEX PHARMA·Filed 2020·Granted Aug 20, 2024·1 cites·18 claims
3282US2023331712A1Solid forms of (r)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1h-indol-5-yl)cyclopropanecarboxamideVERTEX PHARMA·Filed 2022·Application pending·0 cites
3361US2011064811A1Solid forms of N-[2,4-BIS(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamideHURTER PATRICIA·Filed 2006·Application pending·0 cites
3460US2013085158A1Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acidVERTEX PHARMA·Filed 2012·Application pending·0 cites
3560US2014329855A1Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamideVERTEX PHARMA·Filed 2014·Application pending·0 cites
3658US2013158071A1Pharmaceutical compositions and administrations thereofVERTEX PHARMA·Filed 2012·Application pending·0 cites
3758US2019038615A1Pharmaceutical compositions and administrations thereofVERTEX PHARMA·Filed 2018·Application pending·0 cites
3857US2013338188A9Pharmaceutical compositions and administrations thereofVERTEX PHARMA·Filed 2012·Application pending·0 cites
3957US2013131107A1Pharmaceutical compositions and administrations thereofVERTEX PHARMA·Filed 2012·Application pending·0 cites
4056US2018153874A1Pharmaceutical compositions and administrations thereofVERTEX PHARMA·Filed 2017·Application pending·0 cites
4156US2013018071A1Solid Forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamideVERTEX PHARMA·Filed 2012·Application pending·0 cites
4255US9040542B2Solid forms of gyrase inhibitor (R)-1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl)pryimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1H-benzimidazol-2-yl]ureaVERTEX PHARMA·Filed 2013·Granted May 26, 2015·0 cites·16 claims
4352US2016022665A2Pharmaceutical Compositions and Administrations ThereofVERTEX PHARMA·Filed 2015·Application pending·0 cites
4451US2016022664A2Pharmaceutical Compositions and Administrations ThereofVERTEX PHARMA·Filed 2015·Application pending·0 cites
4551US2014113933A9Solid Forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihyroquinoline-3-carboxamideVERTEX PHARMA·Filed 2013·Application pending·0 cites
4649US2016067239A9Pharmaceutical compositions and administrations thereofVERTEX PHARMA·Filed 2015·Application pending·0 cites
4749US2013317222A1Solid forms of gyrase inhibitor (r)-1-ethyl-3-[5-[2-(1-hydroxy-1-methyl-ethyl)pyrimidin-5-yl]-7-(tetrahydrofuran-2-yl]-1h-benzimidazol-2-yl]ureaVERTEX PHARMA·Filed 2013·Application pending·0 cites
4839US2011251253A1Solid forms of (r)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1h-indol-5-yl) cyclopropanecarboxamideVERTEX PHARMA·Filed 2011·Application pending·0 cites

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