Inventor · disambiguated record
Michael C. Holmes
Also filed as: HOLMES MICHAEL · HOLMES MICHAEL C · HOLMES MICHAEL CHRISTOPHER
65 granted patents·32 pending applications·2,028 citations·filing 1999–2024
99Inventor score
Files withSANGAMO BIOSCIENCES INC44SANGAMO THERAPEUTICS INC25GREGORY PHILIP D4HOLMES MICHAEL C4ANDO DALE2
Top patents by PatentIndex Score
97 records- 0199US9597357B2T cell modifying compounds and uses thereofSANGAMO BIOSCIENCES INC·Filed 2013·Granted Mar 21, 2017·111 cites·23 claims
- 0299US7914796B2Engineered cleavage half-domainsSANGAMO BIOSCIENCES INC·Filed 2008·Granted Mar 29, 2011·221 cites·19 claims
- 0399US7888121B2Methods and compositions for targeted cleavage and recombinationSANGAMO BIOSCIENCES INC·Filed 2004·Granted Feb 15, 2011·355 cites·38 claims
- 0498US9045763B2Linear donor constructs for targeted integrationDEKELVER RUSSELL·Filed 2011·Granted Jun 2, 2015·92 cites·23 claims
- 0598US8945868B2Methods and compositions for modification of a HLA locusCOLLINGWOOD TREVOR·Filed 2011·Granted Feb 3, 2015·122 cites·9 claims
- 0698US7951925B2Methods and compositions for gene inactivationSANGAMO BIOSCIENCES INC·Filed 2007·Granted May 31, 2011·213 cites·22 claims
- 0797US9616090B2Gene correction of SCID-related genes in hematopoietic stem and progenitor cellsSANGAMO BIOSCIENCES INC·Filed 2015·Granted Apr 11, 2017·51 cites·19 claims
- 0897US8563314B2Methods and compositions for modulating PD1GREGORY PHILIP D·Filed 2010·Granted Oct 22, 2013·86 cites·41 claims
- 0996US9782437B2Methods and compositions for targeted cleavage and recombinationSANGAMO BIOSCIENCES INC·Filed 2014·Granted Oct 10, 2017·18 cites·8 claims
- 1096US9434776B2Methods and compositions for gene inactivationSANGAMO BIOSCIENCES INC·Filed 2013·Granted Sep 6, 2016·26 cites·23 claims
- 1196US8409861B2Targeted deletion of cellular DNA sequencesGUSCHIN DMITRY·Filed 2005·Granted Apr 2, 2013·187 cites·12 claims
- 1295US8956828B2Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleasesBONINI MARIA CHIARA·Filed 2010·Granted Feb 17, 2015·203 cites·15 claims
- 1394US9937207B2Targeted disruption of T cell receptor genes using talensSANGAMO BIOSCIENCES INC·Filed 2014·Granted Apr 10, 2018·37 cites·13 claims
- 1494US9222105B2Methods and compositions for modification of the HPRT locusSANGAMO BIOSCIENCES INC·Filed 2012·Granted Dec 29, 2015·16 cites·29 claims
- 1594US8569253B2Methods and compositions for gene inactivationANDO DALE·Filed 2011·Granted Oct 29, 2013·16 cites·23 claims
- 1693US10072062B2Methods and compositions for modification of a HLA locusSANGAMO BIOSCIENCES INC·Filed 2015·Granted Sep 11, 2018·11 cites·11 claims
- 1793US10046028B2Methods and compositions for modulating PD1SANGAMO BIOSCIENCES INC·Filed 2016·Granted Aug 14, 2018·7 cites·3 claims
- 1893US8771985B2Genome editing of a Rosa locus using zinc-finger nucleasesCUI XIAOXIA·Filed 2011·Granted Jul 8, 2014·54 cites·20 claims
- 1992US9833479B2Gene correction of SCID-related genes in hematopoietic stem and progenitor cellsSANGAMO THERAPEUTICS INC·Filed 2017·Granted Dec 5, 2017·5 cites·9 claims
- 2092US9629930B2Methods and compositions for treating hemophilia BSANGAMO BIOSCIENCES INC·Filed 2015·Granted Apr 25, 2017·8 cites·18 claims
- 2192US9566352B2Methods and compositions for inhibiting viral entry into cellsHOLMES MICHAEL C·Filed 2011·Granted Feb 14, 2017·22 cites·7 claims
- 2292US8895264B2Methods and compositions for modification of the HPRT locusSANGAMO BIOSCIENCES INC·Filed 2012·Granted Nov 25, 2014·10 cites·17 claims
- 2392US8524221B2Methods and compositions for gene inactivationANDO DALE·Filed 2011·Granted Sep 3, 2013·12 cites·13 claims
- 2491US9957526B2Delivery methods and compositions for nuclease-mediated genome engineeringSANGAMO BIOSCIENCES INC·Filed 2014·Granted May 1, 2018·14 cites·7 claims
- 2591US9260726B2Targeted integration and expression on exogenous nucleic acid sequencesSANGAMO BIOSCIENCES INC·Filed 2013·Granted Feb 16, 2016·7 cites·11 claims
- 2690US9175280B2Methods and compositions for treating hemophilia BGREGORY PHILIP D·Filed 2011·Granted Nov 3, 2015·9 cites·11 claims
- 2789US9752140B2Methods and compostions for targeted genomic deletionSANGAMO BIOSCIENCES INC·Filed 2016·Granted Sep 5, 2017·3 cites·6 claims
- 2888US9574211B2Methods and compositions for prevention or treatment of a diseaseSANGAMO BIOSCIENCES INC·Filed 2015·Granted Feb 21, 2017·4 cites·12 claims
- 2988US9567573B2Genome editing of a Rosa locus using nucleasesGREGORY PHILIP D·Filed 2011·Granted Feb 14, 2017·10 cites·20 claims
- 3088US9121072B2Rapid screening of biologically active nucleases and isolation of nuclease-modified cellsHOLMES MICHAEL C·Filed 2011·Granted Sep 1, 2015·5 cites·17 claims
- 3188US9115409B2Rapid screening of biologically active nucleases and isolation of nuclease-modified cellsSANGAMO BIOSCIENCES INC·Filed 2013·Granted Aug 25, 2015·4 cites·15 claims
- 3287US9765360B2Linear donor constructs for targeted integrationSANGAMO BIOSCIENCES INC·Filed 2016·Granted Sep 19, 2017·2 cites·12 claims
- 3387US9376685B2Linear donor constructs for targeted integrationSANGAMO BIOSCIENCES INC·Filed 2015·Granted Jun 28, 2016·2 cites·11 claims
- 3487US8524500B2Methods and compositions for targeted cleavage and recombinationURNOV FYODOR·Filed 2010·Granted Sep 3, 2013·7 cites·8 claims
- 3586US10907175B2Isolated human cell with an inactivated glucocorticoid receptor geneSANGAMO BIOSCIENCES INC·Filed 2015·Granted Feb 2, 2021·2 cites·7 claims
- 3686US10604771B2Delivery methods and compositions for nuclease-mediated genome engineeringSANGAMO BIOSCIENCES INC·Filed 2014·Granted Mar 31, 2020·7 cites·2 claims
- 3786US8936936B2Methods and compositions for targeted integrationHOLMES MICHAEL C·Filed 2008·Granted Jan 20, 2015·12 cites·16 claims
- 3886US8871905B2Modification of CXCR4 using engineered zinc finger proteinsHOLMES MICHAEL C·Filed 2010·Granted Oct 28, 2014·9 cites·19 claims
- 3986US2025129181A1T cell modifying compounds and uses thereofSANGAMO THERAPEUTICS INC·Filed 2024·Application pending·0 cites
- 4084US10858416B2Methods and compositions for modification of a HLA locusSANGAMO THERAPEUTICS INC·Filed 2018·Granted Dec 8, 2020·1 cites·9 claims
- 4184US10155011B2Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleasesSANGAMO BIOSCIENCES INC·Filed 2015·Granted Dec 18, 2018·4 cites·13 claims
- 4283US9650648B2Methods and compositions for treatment of a genetic conditionSANGAMO BIOSCIENCES INC·Filed 2013·Granted May 16, 2017·4 cites·11 claims
- 4382US11235026B2Methods and compositions for modulating PD1SANGAMO THERAPEUTICS INC·Filed 2018·Granted Feb 1, 2022·1 cites·7 claims
- 4481US9717759B2Modification of CXCR4 using engineered zinc finger proteinsSANGAMO BIOSCIENCES INC·Filed 2014·Granted Aug 1, 2017·2 cites·11 claims
- 4581US9161995B2Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (CFTR) geneGUSCHIN DMITRY M·Filed 2012·Granted Oct 20, 2015·8 cites·19 claims
- 4681US2023416775A1Methods and compositions for treatment of a genetic conditionSANGAMO THERAPEUTICS INC·Filed 2022·Application pending·0 cites
- 4780US9963715B2Methods and compositions for treatment of a genetic conditionSANGAMO BIOSCIENCES INC·Filed 2013·Granted May 8, 2018·3 cites·11 claims
- 4879US10918668B2Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleasesSANGAMO THERAPEUTICS INC·Filed 2018·Granted Feb 16, 2021·1 cites·9 claims
- 4979US9402879B2Methods and compositions for modulating PD1SANGAMO BIOSCIENCES INC·Filed 2013·Granted Aug 2, 2016·2 cites·7 claims
- 5079US2010111907A1Methods and compositions for gene inactivationSANGAMO BIOSCIENCES INC·Filed 2009·Application pending·0 cites
Showing the top 50 of 97 patent records by PatentIndex Score.
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Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →