Inventor · disambiguated record
Varghese John
Also filed as: JOHN VARGHESE
89 granted patents·58 pending applications·767 citations·filing 1994–2025
99Inventor score
Files withELAN PHARM INC44UNIV CALIFORNIA21ATHENA NEUROSCIENCES INC19JOHN VARGHESE12BUCK INST RES AGING11
Top patents by PatentIndex Score
147 records- 0194US7176242B2N,N′-substituted-1,3-diamino-2-hydroxypropane derivativesUPJOHN CO·Filed 2002·Granted Feb 13, 2007·92 cites·20 claims
- 0293US6982264B2Substituted alcohols useful in treatment of Alzheimer's diseaseELAN PHARM INC·Filed 2002·Granted Jan 3, 2006·38 cites·10 claims
- 0392US6627739B1β-secretase enzyme compositions and methodsELAN PHARM INC·Filed 2000·Granted Sep 30, 2003·48 cites·1 claims
- 0491US7468365B2Lactam compoundLILLY CO ELI·Filed 2006·Granted Dec 23, 2008·22 cites·15 claims
- 0591US7262043B2β-secretase enzyme compositions and methodsELAN PHARM INC·Filed 2005·Granted Aug 28, 2007·9 cites·4 claims
- 0691US6653303B1Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compoundsATHENA NEUROSCIENCES INC·Filed 2003·Granted Nov 25, 2003·16 cites·30 claims
- 0790US7034182B2Compounds to treat Alzheimer's diseaseELAN PHARM INC·Filed 2001·Granted Apr 25, 2006·37 cites·45 claims
- 0889US7727997B2N,N′-substituted-1,3-diamino-2-hydroxypropane derivativesELAN PHARM INC·Filed 2006·Granted Jun 1, 2010·21 cites·27 claims
- 0989US6544978B2Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compoundsATHENA NEUROSCIENCES INC·Filed 2001·Granted Apr 8, 2003·16 cites·32 claims
- 1088US7223774B2Benzamide 2-hydroxy-3-diaminoalkanesELAN PHARM INC·Filed 2004·Granted May 29, 2007·34 cites·13 claims
- 1187US9926280B2Hydantoins that modulate BACE-mediated APP processingBUCK INST RES AGING·Filed 2015·Granted Mar 27, 2018·4 cites·16 claims
- 1287US6541466B2Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compoundsATHENA NEUROSCIENCES INC·Filed 2001·Granted Apr 1, 2003·10 cites·32 claims
- 1385US10835546B2App specific BACE inhibitors (ASBIs) and uses thereofBUCK INST RES AGING·Filed 2019·Granted Nov 17, 2020·1 cites·16 claims
- 1485US6211235B1Compounds for inhibiting β-amyloid peptide release and/or its synthesisELAN PHARM INC·Filed 1998·Granted Apr 3, 2001·46 cites·29 claims
- 1584US10202355B2Hydantoins that modulate bace-mediated app processingBUCK INST RES AGING·Filed 2014·Granted Feb 12, 2019·4 cites·8 claims
- 1684US7514408B1β-secretase enzyme compositions and methodsELAN PHARM INC·Filed 2000·Granted Apr 7, 2009·10 cites·6 claims
- 1784US7252963B2β-secretase enzyme compositions and methodsELAN PHARM INC·Filed 2005·Granted Aug 7, 2007·10 cites·5 claims
- 1884US6992081B2Compounds to treat Alzheimer's diseaseELAN PHARM INC·Filed 2001·Granted Jan 31, 2006·13 cites·8 claims
- 1984US6737420B2Compounds to treat Alzheimer's diseaseELAN PHARM INC·Filed 2001·Granted May 18, 2004·14 cites·13 claims
- 2084US5484940ASubstituted 3-indolyl-5-pyrazolone compoundsFiled 1994·Granted Jan 16, 1996·27 cites·11 claims
- 2183US7276349B2Beta-secretase enzyme compositions and methodsELAN PHARM INC·Filed 2005·Granted Oct 2, 2007·9 cites·3 claims
- 2283US7030239B2Compounds to treat Alzheimer's diseaseELAN PHARM INC·Filed 2004·Granted Apr 18, 2006·13 cites·5 claims
- 2382US7544717B22-amino- and 2-thio- substituted 1,3-diaminopropanesELAN PHARM INC·Filed 2005·Granted Jun 9, 2009·9 cites·14 claims
- 2482US7385085B2Oxime derivative substituted hydroxyethylamine aspartyl protease inhibitorsELAN PHARM INC·Filed 2005·Granted Jun 10, 2008·6 cites·10 claims
- 2582US7276484B2Dipeptide inhibitors of β-secretaseELAN PHARM INC·Filed 2005·Granted Oct 2, 2007·4 cites·5 claims
- 2682US7244725B2Acetyl 2-hydroxy-1, 3-diaminoalkanesUPJOHN CO·Filed 2003·Granted Jul 17, 2007·16 cites·14 claims
- 2782US7214715B2Compounds to treat Alzheimer's diseaseELAN PHARM INC·Filed 2001·Granted May 8, 2007·18 cites·100 claims
- 2880US7858642B2Substituted hydroxyethylamine aspartyl protease inhibitorsELAN PHARM INC·Filed 2009·Granted Dec 28, 2010·5 cites·24 claims
- 2980US6846813B2Compounds to treat alzheimer's diseaseUPJOHN CO·Filed 2001·Granted Jan 25, 2005·10 cites·72 claims
- 3080US5994398AArylsulfonamides as phospholipase A2 inhibitorsELAN PHARM INC·Filed 1996·Granted Nov 30, 1999·27 cites·40 claims
- 3177US7109017B1β-secretase enzyme compositions and methodsELAN PHARM INC·Filed 2000·Granted Sep 19, 2006·13 cites·18 claims
- 3276US10357508B2APP specific BACE inhibitors (ASBIs) and uses thereofBUCK INST RES AGING·Filed 2013·Granted Jul 23, 2019·2 cites·11 claims
- 3376US6888022B2Methods and compounds for inhibiting β-amyloid peptide release and/or its synthesisLILLY CO ELI·Filed 2001·Granted May 3, 2005·4 cites·71 claims
- 3476US6864240B1Dipeptide inhibitors of β-secretaseELAN PHARM INC·Filed 2000·Granted Mar 8, 2005·3 cites·37 claims
- 3576US6476263B1Compounds for inhibiting β-amyloid peptide release and/or its synthesisELAN PHARM INC·Filed 2001·Granted Nov 5, 2002·5 cites·28 claims
- 3676US6096782AN-(aryl/heteroaryl) amino acid derivatives pharmaceutical compositions comprising same and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compoundsATHENA NEUROSCIENCES INC·Filed 1997·Granted Aug 1, 2000·18 cites·27 claims
- 3775US7115410B1β-secretase enzyme compositions and methodsELAN PHARM INC·Filed 2000·Granted Oct 3, 2006·16 cites·14 claims
- 3875US7067271B1β-secretase enzyme compositions and methodsELAN PHARM INC·Filed 2000·Granted Jun 27, 2006·12 cites·4 claims
- 3975US6559141B2Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compoundsATHENA NEUROSCIENCES INC·Filed 2001·Granted May 6, 2003·2 cites·32 claims
- 4074US6861558B2Methods and compounds for inhibiting β-amyloid peptide release and/or its synthesisELAN PHARM INC·Filed 2002·Granted Mar 1, 2005·2 cites·7 claims
- 4172US11091444B2Hydantoins that modulate BACE-mediated app processingBUCK INST RES AGING·Filed 2020·Granted Aug 17, 2021·0 cites·12 claims
- 4271US7645780B2Acetyl 2-hydroxy-1, 3-diaminoalkanesELAN PHARM INC·Filed 2006·Granted Jan 12, 2010·1 cites·14 claims
- 4371US6579867B2Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compoundsATHENA NEUROSCIENCES INC·Filed 2001·Granted Jun 17, 2003·2 cites·14 claims
- 4469US7169759B1Tetrapeptide inhibitors of β-secretaseELAN PHARM INC·Filed 2000·Granted Jan 30, 2007·1 cites·111 claims
- 4569US6951854B1Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compoundsLILLY CO ELI·Filed 2004·Granted Oct 4, 2005·0 cites·13 claims
- 4669US2006079499A1Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compoundsWU JING·Filed 2004·Application pending·0 cites
- 4769US2009144840A1Beta-secretase enzyme compositions and methodsELAN PHARM INC·Filed 2008·Application pending·0 cites
- 4868US7338965B23,4-disubstituted, 3,5-disubstituted and 3,4,5-substituted piperidinesUPJOHN CO·Filed 2002·Granted Mar 4, 2008·4 cites·10 claims
- 4968US7119085B2Methods to treat alzheimer's diseaseELAN PHARM INC·Filed 2001·Granted Oct 10, 2006·2 cites·10 claims
- 5066US12157740B2Triazolopyridines and triazolopyrimidines that lower stress-induced p-tauNANTNEURO LLC·Filed 2021·Granted Dec 3, 2024·0 cites·3 claims
Showing the top 50 of 147 patent records by PatentIndex Score.
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Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →