Inventor · disambiguated record
William Markland
Also filed as: MARKLAND WILLIAM
28 granted patents·5 pending applications·14,431 citations·filing 1991–2021
98Inventor score
Top patents by PatentIndex Score
33 records- 0198US6423498B1Variegated Kunitz domain peptide library and uses thereofDYAX CORP·Filed 2000·Granted Jul 23, 2002·143 cites·4 claims
- 0298US5571698ADirected evolution of novel binding proteinsPROTEIN ENG CORP·Filed 1993·Granted Nov 5, 1996·2.7k cites·83 claims
- 0398US5403484AViruses expressing chimeric binding proteinsPROTEIN ENG CORP·Filed 1993·Granted Apr 4, 1995·2.9k cites·49 claims
- 0498US5223409ADirected evolution of novel binding proteinsPROTEIN ENG CORP·Filed 1991·Granted Jun 29, 1993·6.9k cites·66 claims
- 0597US7919462B2Inhibitors of human plasmin derived from the Kunitz domainsDYAX CORP·Filed 2007·Granted Apr 5, 2011·29 cites·14 claims
- 0697US7628983B2Kallikrein-binding “Kunitz domain” proteins and analogues thereofDYAX CORP·Filed 2006·Granted Dec 8, 2009·48 cites·13 claims
- 0797US5837500ADirected evolution of novel binding proteinsDYAX CORP·Filed 1995·Granted Nov 17, 1998·595 cites·43 claims
- 0897US5663143AEngineered human-derived kunitz domains that inhibit human neutrophil elastaseDYAX CORP·Filed 1994·Granted Sep 2, 1997·272 cites·9 claims
- 0996US6071723AInhibitors of human plasmin derived from the Kunitz domainsDYAX CORP·Filed 1999·Granted Jun 6, 2000·78 cites·20 claims
- 1096US6057287AKallikrein-binding "Kunitz domain" proteins and analogues thereofDYAX CORP·Filed 1994·Granted May 2, 2000·125 cites·8 claims
- 1195US8283321B2Kallikrein-binding “Kunitz domain” proteins and analogues thereofMARKLAND WILLIAM·Filed 2009·Granted Oct 9, 2012·38 cites·12 claims
- 1295US7208293B2Directed evolution of novel binding proteinsDYAX CORP·Filed 2001·Granted Apr 24, 2007·94 cites·13 claims
- 1395US7118879B2Method of recovering a nucleic acid encoding a proteinaceous binding domain which binds a target materialDYAX CORP·Filed 2002·Granted Oct 10, 2006·80 cites·26 claims
- 1495US6333402B1Kallikrein-binding “Kunitz domain” proteins and analogues thereofDYAX CORP·Filed 1999·Granted Dec 25, 2001·115 cites·7 claims
- 1595US6010880AInhibitors of human plasmin derived from the kunitz domainsDYAX CORP·Filed 1995·Granted Jan 4, 2000·102 cites·16 claims
- 1694US6979538B2Directed evolution of novel binding proteinsDYAX CORP·Filed 2001·Granted Dec 27, 2005·80 cites·19 claims
- 1794US6103499AInhibitors of human plasmin derived from the Kunitz domainsDYAX CORP·Filed 1999·Granted Aug 15, 2000·79 cites·16 claims
- 1893US7893007B2Directed evolution of novel binding proteinsDYAX CORP·Filed 2008·Granted Feb 22, 2011·22 cites·19 claims
- 1993US7413537B2Directed evolution of disulfide-bonded micro-proteinsDYAX CORP·Filed 2002·Granted Aug 19, 2008·40 cites·34 claims
- 2092US6953674B2Inhibitors of human plasmin derived from the kunitz domainsDYAX CORP·Filed 2002·Granted Oct 11, 2005·31 cites·56 claims
- 2191US7078383B2ITI-D1 Kunitz domain mutants as HNE inhibitorsDYAX CORP·Filed 2002·Granted Jul 18, 2006·28 cites·10 claims
- 2282US7383135B1Methods of designing inhibitors for JNK kinasesVERTEX PHARMA·Filed 2000·Granted Jun 3, 2008·9 cites·4 claims
- 2373US11110108B2Method for treating cancer using a combination of DNA-damaging agents and DNA-PK inhibitorsVERTEX PHARMA·Filed 2017·Granted Sep 7, 2021·1 cites·37 claims
- 2469US8002891B2Crystallization of C-Jun N-Terminal Kinase 3 (JNK3)VERTEX PHARMA·Filed 2008·Granted Aug 23, 2011·0 cites·5 claims
- 2566US2009023651A1Inhibitors of human plasmin derived from the kunitz domainsDYAX COPR A DELAWARE CORP·Filed 2007·Application pending·0 cites
- 2662US11980633B2Method for treating cancer using a combination of DNA-damaging agents and DNA-PK inhibitorsVERTEX PHARMA·Filed 2021·Granted May 14, 2024·0 cites·20 claims
- 2760US8431359B2Nucleic acids encoding polypeptide inhibitors of human plasmin derived from the Kunitz domainsMARKLAND WILLIAM·Filed 2005·Granted Apr 30, 2013·0 cites·38 claims
- 2860US2011152193A1Inhibitors of human plasmin derived from the kunitz domainsDYAX CORP·Filed 2011·Application pending·0 cites
- 2959US8663629B2Kallikrein-binding “kunitz domain” proteins and analogues thereofMARKLAND WILLIAM·Filed 2012·Granted Mar 4, 2014·0 cites·9 claims
- 3058US2007259417A1Directed evolution of novel binding proteinsDYAX CORP·Filed 2007·Application pending·0 cites
- 3153US2006134087A1ITI-D1 Kunitz domain mutants as hNE inhibitorsDYAX CORP·Filed 2005·Application pending·0 cites
- 3249US2003223977A1Kunitz domain mutants as cathepsin G inhibitorsFiled 2002·Application pending·0 cites
- 3335US7256094B2Method for changing threshold voltage of device in resist asherATMEL CORP·Filed 2005·Granted Aug 14, 2007·0 cites·29 claims
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Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →