P
US10000523B2ActiveUtilityPatentIndex 94

β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment

Assignee: ATEA PHARMACEUTICALS INCPriority: Mar 6, 2015Filed: Oct 12, 2017Granted: Jun 19, 2018
Est. expiryMar 6, 2035(~8.7 yrs left)· nominal 20-yr term from priority
Inventors:SOMMADOSSI JEAN-PIERREMOUSSA ADEL
A61P 31/14C07H 19/20A61K 31/7076C07H 19/16C07H 19/207
94
PatentIndex Score
20
Cited by
288
References
30
Claims

Abstract

A compound of the structure: or a pharmaceutically acceptable salt or composition thereof for the treatment of a host infected with or exposed to an HCV virus or other disorders more fully described herein.

Claims

exact text as granted — not AI-modified
We claim: 
     
       1. A pharmaceutical composition comprising an anti-HCV effective amount of a compound of the formula: 
       
         
           
           
               
               
           
         
       
       in a pharmaceutically acceptable carrier. 
     
     
       2. The pharmaceutical composition of  claim 1 , comprising an effective amount of a compound of the formula: 
       
         
           
           
               
               
           
         
       
     
     
       3. The pharmaceutical composition of  claim 1 , comprising an effective amount of a compound of the formula: 
       
         
           
           
               
               
           
         
       
     
     
       4. The pharmaceutical composition of  claim 1 , in a dosage form. 
     
     
       5. The pharmaceutical composition of  claim 4 , in an oral dosage form. 
     
     
       6. The pharmaceutical composition of  claim 5 , in a tablet. 
     
     
       7. The pharmaceutical composition of  claim 5 , in a capsule. 
     
     
       8. The pharmaceutical composition of  claim 2 , in a dosage form. 
     
     
       9. The pharmaceutical composition of  claim 8 , in an oral dosage form. 
     
     
       10. The pharmaceutical composition of  claim 9 , in a tablet. 
     
     
       11. The pharmaceutical composition of  claim 9 , in a capsule. 
     
     
       12. The pharmaceutical composition of  claim 3 , in a dosage form. 
     
     
       13. The pharmaceutical composition of  claim 12 , in an oral dosage form. 
     
     
       14. The pharmaceutical composition of  claim 13 , in a tablet. 
     
     
       15. The pharmaceutical composition of  claim 13 , in a capsule. 
     
     
       16. A pharmaceutical composition comprising an anti-HCV effective amount of a compound of the formula: 
       
         
           
           
               
               
           
         
       
       in a pharmaceutically acceptable carrier. 
     
     
       17. The pharmaceutical composition of  claim 16 , comprising an effective amount of a compound of the formula: 
       
         
           
           
               
               
           
         
       
     
     
       18. The pharmaceutical composition of  claim 16 , comprising an effective amount of a compound of the formula: 
       
         
           
           
               
               
           
         
       
     
     
       19. The pharmaceutical composition of  claim 16 , in a dosage form. 
     
     
       20. The pharmaceutical composition of  claim 19 , in an oral dosage form. 
     
     
       21. The pharmaceutical composition of  claim 20 , in a tablet. 
     
     
       22. The pharmaceutical composition of  claim 20 , in a capsule. 
     
     
       23. The pharmaceutical composition of  claim 17 , in a dosage form. 
     
     
       24. The pharmaceutical composition of  claim 23 , in an oral dosage form. 
     
     
       25. The pharmaceutical composition of  claim 24 , in a tablet. 
     
     
       26. The pharmaceutical composition of  claim 24 , in a capsule. 
     
     
       27. The pharmaceutical composition of  claim 18 , in a dosage form. 
     
     
       28. The pharmaceutical composition of  claim 27 , in an oral dosage form. 
     
     
       29. The pharmaceutical composition of  claim 28 , in a tablet. 
     
     
       30. The pharmaceutical composition of  claim 28 , in a capsule.

Cited by (0)

No later patents cite this yet.

References (0)

No backward citations on record.