Multicomponent and biocompatible nanocomposite materials, methods of synthesizing same and applications of same

Abstract

One aspect of the present invention relates to a multicomponent and biocompatible nanocomposite material, including a graphene structure formed with a plurality of graphene layers; and gold/hydroxyapatite (Au/HA) nanoparticles distributed within the graphene structure; where the nanocomposite material is formed by heating an Au/HA catalyst thin film with a carbon source gas to perform radio frequency chemical vapor deposition (RF-CVD).

What is claimed is: 
     
       1. A multicomponent and biocompatible nanocomposite material, comprising:
 (a) a graphene structure formed with a plurality of graphene layers; and 
 (b) gold/hydroxyapatite (Au/HA) nanoparticles distributed within the graphene structure, wherein the Au/HA nanoparticles comprise HA structures and Au nanoparticles deposited over surfaces of the HA structures, 
 wherein the nanocomposite material is formed by heating an Au/HA catalyst thin film in a reactor with a carbon source gas to perform radio frequency chemical vapor deposition (RF-CVD), wherein the nanocomposite material has a flattened structure with rounded edges, and comprises a graphene matrix and is applied in an area of bone regeneration, and wherein the Au/HA nanoparticles are formed by Au/HA catalyst and distributed within the graphene matrix. 
 
     
     
       2. The nanocomposite material of  claim 1 , wherein the carbon source gas comprises acetylene (C 2 H 2 ). 
     
     
       3. The nanocomposite material of  claim 1 , wherein the carbon source gas comprises methane (CH 4 ). 
     
     
       4. The nanocomposite material of  claim 1 , wherein the Au/HA catalyst thin film is formed by:
 (a) immersing HA nanocrystals and gold trichloride trihydrate (HAuCl 4 .3H 2 O) in water to form a mixture; 
 (b) stirring the mixture at a stirring temperature such that the Au nanoparticles deposits on the HA nanocrystals; 
 (c) drying the mixture at a drying temperature to obtain the Au/HA catalyst; and 
 (d) distributing the Au/HA catalyst to form the Au/HA catalyst thin film. 
 
     
     
       5. The nanocomposite material of  claim 4 , wherein the stirring temperature is about 70-90° C., and the drying temperature is about 100° C. 
     
     
       6. The nanocomposite material of  claim 1 , wherein the first flow rate is about 150-600 ml/min, and the first period is about 5-20 minutes, and the first temperature is about 400-600° C. 
     
     
       7. The nanocomposite material of  claim 6 , wherein the third flow rate is about 5-30 ml/min, and the third time is about 15-90 minutes. 
     
     
       8. The nanocomposite material of  claim 6 , wherein the third flow rate is about 40-240 ml/min, and the third time is about 15-60 minutes. 
     
     
       9. The nanocomposite material of  claim 1 , wherein Au nanoclusters are uniformly arranged over the surfaces of HA particles with diameters between about 2 nm and 7 nm. 
     
     
       10. The nanocomposite material of  claim 1 , wherein the Au nanoparticles have uniform sizes and slightly elliptic shapes with average minor and major dimensions of about 3.6±0.5 nm and about 4.1±0.5 nm, respectively. 
     
     
       11. The nanocomposite material of  claim 1 , wherein the heating the Au/HA catalyst thin film in the reactor comprising:
 introducing an inert gas to the reactor at a first flow rate for a first time; 
 heating the reactor to a first temperature; 
 introducing hydrogen to the reactor at a flow rate about 50-300 ml/min for 5-20 minutes; 
 heating the reactor to a second temperature from 750° C. to 810° C. or from 900° C. to 1000° C. or; 
 introducing the carbon source gas to the reactor at a third flow rate for a third time; and 
 cooling the reactor.