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US10308642B2ActiveUtilityPatentIndex 64

Anti-hepatitis B virus agent

Assignee: FUJIFILM TOYAMA CHEMICAL CO LTDPriority: Oct 5, 2015Filed: Oct 5, 2016Granted: Jun 4, 2019
Est. expiryOct 5, 2035(~9.3 yrs left)· nominal 20-yr term from priority
Inventors:SHIMANE KazukiTANAKA YASUHITO
A61K 31/443A61K 31/4422C07D 213/80C07D 405/10A61K 31/4439A61K 31/4436A61P 31/20C07D 409/10C07D 409/04
64
PatentIndex Score
3
Cited by
15
References
9
Claims

Abstract

An anti-hepatitis B virus agent comprising a compound represented by general formula [1], wherein R 1 represents an aryl group, which may be substituted, or the like; R 2 represents an aryl group, which may be substituted, or the like; and R 3 represents a hydrogen atom or the like; or a salt thereof.

Claims

exact text as granted — not AI-modified
The invention claimed is: 
     
       1. A method of treating hepatitis B virus, the method comprising administering an anti-hepatitis B virus agent to a patient in need thereof, the anti-hepatitis B virus agent comprising a compound represented by general formula [1]: 
       
         
           
           
               
               
           
         
         wherein R 1  represents an aryl group which may be substituted or a heterocyclic group which may be substituted; 
         R 2  represents a C 3-8  cycloalkyl group which may be substituted, an aryl group which may be substituted, or a heterocyclic group which may be substituted; and 
         R 3  represents a hydrogen atom or a carboxyl protecting group, or a salt thereof. 
       
     
     
       2. The method according to  claim 1 , wherein R 1  represents an aryl group which may be substituted. 
     
     
       3. The method according to  claim 1 , wherein R 1  represents a phenyl group which may be substituted. 
     
     
       4. The method according to  claim 1 , wherein R 1  represents a heterocyclic group which may be substituted. 
     
     
       5. The method according to  claim 1 , wherein R 1  represents a bicyclic heterocyclic group which may be substituted. 
     
     
       6. The method according to  claim 1 , wherein R 2  represents an aryl group which may be substituted. 
     
     
       7. The method according to  claim 1 , wherein R 2  represents a phenyl group which may be substituted. 
     
     
       8. The method according to  claim 1 , wherein R 2  represents a heterocyclic group which may be substituted. 
     
     
       9. The method according to  claim 1 , wherein R 2  represents a monocyclic heterocyclic group which may be substituted.

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