Method for relieving memory dysfunction using Puerariae radix extract

Abstract

A method for relieving memory dysfunction using Puerariae Radix Extract is provided, including decocting Puerariae Radix in water, concentrating the extracted product thereof, and administrating an effective dose of the Puerariae Radix extract to a subject. Since the present invention merely uses Puerariae Radix as an ingredient, it belongs to a Chinese herbal medicine of single drug prescription. Further, with the same amount of Puerarin, Puerariae Radix Extract of the present invention provides a better neuroprotective effect in comparison with Puerarin, which indicates that the Puerariae Radix extract contains more active neurotrophic ingredients other than Puerarin. Therefore, Puerariae Radix extract is more promising potential therapeutic medicine than Puerarin for relieving the symptoms of anxiety and cognitive impairment.

What is claimed is: 
     
       1. A method for relieving memory dysfunction using a Puerariae Radix extract, comprising:
 decocting a Puerariae Radix in water followed by concentrating the Puerariae Radix extract; and 
 administrating an effective dose of the Puerariae Radix extract into a subject, 
 wherein the Puerariae Radix extract comprises daidzein, daidzin and puerarin, and a ratio of daidzein, daidzin and puerarin is in a range of 1:1˜30:50˜100. 
 
     
     
       2. The method as in  claim 1 , wherein Chinese herbs decocted is limited to only the Puerariae Radix. 
     
     
       3. The method as in  claim 1 , wherein the effective dose is 1˜1000 mg/kg. 
     
     
       4. The method as in  claim 1 , wherein the administrating further comprises administrating four times per day to once per week. 
     
     
       5. The method as in  claim 1 , wherein the administrating comprises administrating by means of an injection, orally, or topically. 
     
     
       6. The method as in  claim 1 , wherein the method further comprises functions of reducing β-amyloid accumulation, hyperphosphorylation of tau protein, and neuroinflammation, and increasing expression of synapse related proteins, a number of noradrenergic neurons, and a number of serotonergic neurons.