P
US10869883B2ActiveUtilityPatentIndex 60

Nutrient composition having lipid metabolism-improving action

Assignee: DAICEL CORPPriority: Dec 20, 2013Filed: Jan 25, 2019Granted: Dec 22, 2020
Est. expiryDec 20, 2033(~7.5 yrs left)· nominal 20-yr term from priority
Inventors:SHIMAMOTO SHUNAKAMURA TOSHIKAZUUKITA SHIZUKANAKAMURA TSUYOSHIYAMAUCHI RYOKOKOBAYASHI HIROSHI
C08L 1/14C08L 1/12C08B 3/28C08B 3/24C08B 3/06A23K 50/75A23K 50/10A61P 1/00A61P 37/02A61K 45/06A23K 50/30A23L 33/24A61K 2300/00A61P 1/16A61K 31/717A61P 1/04A61P 3/04A23K 20/163A61P 35/00A23V 2002/00A61P 3/10A61P 3/06A23K 50/40Y02A40/70
60
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Cited by
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References
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Claims

Abstract

A nutrient composition contains a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1. The cellulose acetate may have a compositional distribution index (CDI) of 2.0 or less, where the CDI is specified by the formula: CDI =(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) where the measured value of half height width of chemical composition represents the half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample); and [Math. 1] the theoretical value of half height width of chemical composition =2.35482√{square root over (3* DPw *( DS/ 3)*(1− DS/ 3))}/ DPw where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

Claims

exact text as granted — not AI-modified
The invention claimed is: 
     
       1. A nutrient composition comprising
 a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1, 
 wherein the cellulose acetate comprises a cellulose acetate material prepared under effective hydrolysis and precipitation conditions to obtain a compositional distribution index (CDI) of 2.0 or less, where the compositional distribution index is specified by the formula:
     CDI =(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) 
 
 
       wherein:
 the measured value of half height width of chemical composition is a half height width of chemical composition determined by high-performance liquid chromatographic (HPLC) analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate material; and 
 the theoretical value of half height width of chemical composition is specified by a formula Math.1: 
 
       [Math.1]
 Theoretical value of half height width of chemical composition
   =2.35482√{square root over (3* DPw *( DS/ 3)*(1− DS/ 3))}/ DPw  
 
 
 
       wherein:
 DS is the total degree of acetyl substitution; and 
 DPw is a weight-average degree of polymerization determined by a gel permeation chromatography (GPC)-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate material. 
 
     
     
       2. A livestock feed comprising
 a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1, 
 wherein the cellulose acetate comprises a cellulose acetate material prepared under effective hydrolysis and precipitation conditions to obtain a compositional distribution index (CDI) of 2.0 or less, where the compositional distribution index is specified by the formula:
     CDI =(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) 
 
 
       wherein:
 the measured value of half height width of chemical composition is a half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate material; and 
 the theoretical value of half height width of chemical composition is specified by a formula Math.1: 
 
       [Math.1]
 Theoretical value of half height width of chemical composition
   =2.35482√{square root over (3* DPw *( DS/ 3)*(1− DS/ 3))}/ DPw  
 
 
 
       wherein:
 DS is the total degree of acetyl substitution; and 
 DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate material. 
 
     
     
       3. A lipid metabolism-improving agent comprising
 a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1, 
 wherein the cellulose acetate comprises a cellulose acetate material prepared under effective hydrolysis and precipitation conditions to obtain a compositional distribution index (CDI) of 2.0 or less, where the compositional distribution index is specified by the formula:
     CDI =(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) 
 
 
       wherein:
 the measured value of half height width of chemical composition is a half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate material; and 
 the theoretical value of half height width of chemical composition is specified by a formula Math.1: 
 
       [Math.1]
 Theoretical value of half height width of chemical composition
   =2.35482√{square root over (3* DPw *( DS/ 3)*(1− DS/ 3))}/ DPw  
 
 
 
       wherein:
 DS is the total degree of acetyl substitution; and 
 DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate material. 
 
     
     
       4. The lipid metabolism-improving agent according to  claim 3 , wherein the agent is for livestock. 
     
     
       5. An improving agent for inflammatory bowel diseases or immune disorder, the agent comprising
 a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1, 
 wherein the cellulose acetate comprises a cellulose acetate material prepared under effective hydrolysis and precipitation conditions to obtain a compositional distribution index (CDI) of 2.0 or less, where the compositional distribution index is specified by the formula:
     CDI =(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) 
 
 
       wherein:
 the measured value of half height width of chemical composition is a half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate material; and 
 the theoretical value of half height width of chemical composition is specified by a formula Math.1: 
 
       [Math. 1]
 Theoretical value of half height width of chemical composition
   =2.35482√{square root over (3* DPw *( DS/ 3)*(1− DS/ 3))}/ DPw  
 
 
 
       wherein:
 DS is the total degree of acetyl substitution; and 
 DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate material. 
 
     
     
       6. The improving agent according to  claim 5  for inflammatory bowel diseases or immune disorder,
 wherein the agent is for livestock.

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