Vibrio parahaemolyticus bacteriophage Vib-PAP-5 and use thereof for suppressing proliferation of Vibrio parahaemolyticus bacteria

Abstract

The present invention relates to a Myoviridae bacteriophage Vib-PAP-5 (accession number KCTC 13029BP) isolated from nature characterized by having a capability for specifically killing Vibrio parahaemolyticus bacteria and having a genome expressed by the SEQ ID NO:1, and to a method for preventing and treating infections from Vibrio parahaemolyticus bacteria by means of a composition comprising the Myoviridae bacteriophage Vib-PAP-5 as an active ingredient.

The invention claimed is: 
     
       1. A method for treating a  Vibrio parahaemolyticus  infection, the method comprising: administering to an animal other than a human a composition comprising an isolated Myoviridae bacteriophage Vib-PAP-5 (Accession number: KCTC 13029BP) that can kill  Vibrio parahaemolyticus  specifically as an active ingredient, wherein the Myovirdae bacteriophage Vib-PAP-5 is prepared by bacterial culture with inoculum of bacteriophage Vib-PAP-5 and comprises a genome encoded by the nucleotide sequence of SEQ ID NO:1, wherein the composition is administered as a feed additive or a medicine bath agent. 
     
     
       2. The method of  claim 1 , wherein said composition further comprises a pharmaceutically acceptable carrier. 
     
     
       3. The method of  claim 2 , wherein said composition for the medicine bath agent comprises the bacteriophage Vib-PAP-5 at a concentration of 1×10 1  pfu/ml to 1×10 30  pfu/ml. 
     
     
       4. The method of  claim 2 , wherein said composition for the food additive comprises the bacteriophage Vib-PAP-5 at a concentration of 1×10 1  pfu/g to 1×10 30  pfu/g.