Malodor counteracting ingredients

Abstract

The various aspects presented herein relate to the perfumery industry. More particularly, the various aspects presented herein relate to malodor counteracting compositions and/or ingredients, methods for counteracting malodors, as well as to the perfumed articles or perfuming compositions comprising as an active ingredient, at least one compound selected 5 from the group consisting of: 1-(2-methyl-4-tricyclo[5.2.1.01,5]decanyl)ethyl acetate, 1-(2,4-di-methyl-4-tricyclo[5.2.1.01,5]decanyl)ethyl acetate, 1-((1R,3S,3aS,6S)-1,2,3-trimethyloctahydro-3a,6-methanoinden-1-yl)ethan-1-one, 1-(2,4-dimethyl-4-tricyclo[5.2.1.0{circumflex over ( )}{1,5}]decanyl)ethanone, 2,3,4-trimethyltricyclo[5.2.1.0{circumflex over ( )}{1,5}]decane-4-carbaldehyde, (2,3,4-trimethyl-4-tricyclo[5.2.1.0{circumflex over ( )}{1,5}]decanyl)methyl acetate, 1-((3aS,6S)-10 2,3-dimethyloctahydro-3a,6-methanoinden-1-yl)ethan-1-one oxime, 1,3-dimethyloctahydro-3a,6-methanoindene-1-carbaldehyde oxime, ˜{N}-[1-[(1˜{R},7˜{R})-2,3,4-trimethyl-4-tricyclo[5.2.1.01,5]decanyl]ethylidene]hydroxylamine, (+−)-1-(2,4-dimethyltricyclo[5.2.1.01,5]dec-4-yl) ethanone, (+−)-1-(2,4-dimethyltricyclo[5.2.1.0˜1.5˜]dec-4-yl) ethyl acetate, 1-[(1RS,2RS,4SR,7RS)-2,3,4-trimethyltricyclo[5.2.1.01.˜]dec-4-yl) 15 ethanone, (E/Z)-1-[(1RS,7RS)-2,3-dimethyltricyclo[5.2.1.01,5]dec-4-yl) ethanone oxime, (E/Z)-1-[(1S,7S)-2,3,4-trimethyltricyclo[5.2.1.0˜1.5˜]dec-4-yl) ethanone oxime, (E/Z)-1-((3aS,6S)-1,2,3-trimethyloctahydro-3a,6-methanoinden-1-yl)ethanone oxime, (+−)-1-(3-methyloctahydro-3a,6-methanoinden-1-yl)ethyl acetate, and mixtures thereof.

The invention claimed is: 
     
       1. A method for reducing, preventing, or inhibiting a perception of malodor in a subject, the method comprising,
 contacting a subject with at least one compound selected from the group consisting of: 1-(2-methyl-4-tricyclo[5.2.1.0 1,5 ]decanyl)ethyl acetate, 1-(2,4-dimethyl-4-tricyclo[5.2.1.0 1,5 ]decanyl)ethyl acetate, 1-((1R,3S,3aS,6S)-1,2,3-trimethyloctahydro-3a,6-methanoinden-1-yl)ethan-1-one, 1-(2,4-dimethyl-4-tricyclo[5.2.1.0{circumflex over ( )}{1,5}]decanyl)ethanone, 2,3,4-trimethyltricyclo[5.2.1.0{circumflex over ( )}{1,5}]decane-4-carbaldehyde, (2,3,4-trimethyl-4-tricyclo[5.2.1.0{circumflex over ( )}{1,5}]decanyl)methyl acetate, 1-((3aS,6S)-2,3-dimethyloctahydro-3a,6-methanoinden-1-yl)ethan-1-one oxime, 1,3-dimethyloctahydro-3a,6-methanoindene-1-carbaldehyde oxime, ˜{N}-[1-[(1˜{R},7˜{R})-2,3,4-trimethyl-4-tricyclo[5.2.1.0 1,5 ]decanyl]ethylidene]hydroxylamine, (+−)-1-(2,4-dimethyltricyclo[5.2.1.0 1,5 ]dec-4-yl)ethanone, (+−)-1-(2,4-dimethyltricyclo-[5.2.1.0˜1.5˜]dec-4-yl) ethyl acetate, 1-[(1RS,2RS,4SR,7RS)-2,3,4-trimethyltricyclo-[5.2.1.0 1. ˜]dec-4-yl) ethanone, (E/Z)-1-[(1RS,7RS)-2,3-dimethyltricyclo[5.2.1.0 1.5 ]dec-4-yl) ethanone oxime, (E/Z)-1-[(1S,7S)-2,3,4-trimethyltricyclo[5.2.1.0˜1.5˜]dec-4-yl) ethanone oxime, (E/Z)-1-((3aS,6S)-1,2,3-trimethyloctahydro-3a,6-methanoinden-1-yl)ethanone oxime, (+−)-1-(3-methyloctahydro-3a,6-methanoinden-1-yl)ethyl acetate, and mixtures thereof, 
 wherein the subject is contacted with the at least one compound in an amount sufficient to reduce, prevent, or inhibit the subject's perception of malodor. 
 
     
     
       2. The method of  claim 1 , wherein the amount sufficient to reduce, prevent, or inhibit the subject's perception of malodor inhibits at least one olfactory malodor receptor in the subject. 
     
     
       3. The method of  claim 2 , wherein the at least one olfactory malodor receptor is a butyric acid olfactory receptor. 
     
     
       4. The method of  claim 1 , wherein the malodor is selected from the group consisting of: latrine malodor, laundry malodor, and sweat malodor. 
     
     
       5. A method for inhibiting a butyric acid receptor in a subject, the method comprising,
 contacting a butyric acid receptor in a subject with at least one compound selected from the group consisting of: 1-(2-methyl-4-tricyclo[5.2.1.0 1,5 ]decanyl)ethyl acetate, 1-(2,4-dimethyl-4-tricyclo[5.2.1.0 1,5 ]decanyl)ethyl acetate, 1-((1R,3S,3aS,6S)-1,2,3-trimethyloctahydro-3a,6-methanoinden-1-yl)ethan-1-one, 1-(2,4-dimethyl-4-tricyclo[5.2.1.0{circumflex over ( )}{1,5}]decanyl)ethanone, 2,3,4-trimethyltricyclo-[5.2.1.0{circumflex over ( )}{1,5}]decane-4-carbaldehyde, (2,3,4-trimethyl-4-tricyclo[5.2.1.0{circumflex over ( )}{1,5}]decanyl)methyl acetate, 1-((3aS,6S)-2,3-dimethyloctahydro-3a,6-methanoinden-1-yl)ethan-1-one oxime, 1,3-dimethyloctahydro-3a,6-methanoindene-1-carbaldehyde oxime, ˜{N}-[1-[(1˜{R},7˜{R})-2,3,4-trimethyl-4-tricyclo[5.2.1.0 1,5 ]decanyl]ethylidene]hydroxylamine, (+−)-1-(2,4-dimethyltricyclo[5.2.1.0 1,5 ]dec-4-yl) ethanone, (+−)-1-(2,4-dimethyltricyclo-[5.2.1.0˜1.5˜]dec-4-yl) ethyl acetate, 1-[(1RS,2RS,4SR,7RS)-2,3,4-trimethyltricyclo-[5.2.1.0 1, ˜]dec-4-yl) ethanone, (E/Z)-1-[(1RS,7RS)-2,3-dimethyltricyclo[5.2.1.0 1,5 ]dec-4-yl) ethanone oxime, (E/Z)-1-[(1S,7S)-2,3,4-trimethyltricyclo[5.2.1.0˜1.5˜]dec-4-yl) ethanone oxime, (E/Z)-1-((3aS,6S)-1,2,3-trimethyloctahydro-3a,6-methanoinden-1-yl)ethanone oxime, (+−)-1-(3-methyloctahydro-3a,6-methanoinden-1-yl)ethyl acetate, and mixtures thereof, 
 wherein the subject is contacted with the at least one compound in an amount sufficient to inhibit the butyric acid receptor. 
 
     
     
       6. The method of  claim 5 , wherein the inhibition of the at least one butyric acid olfactory receptor inhibits, reduces, suppresses, or inhibits the perception of a malodor in the subject. 
     
     
       7. The method of  claim 6 , wherein the malodor comprises butyric acid.