Sulfobetaine group-comprising reactive compound, polymer thereof, and method of producing the polymer

Abstract

A polymer comprising at least 1% by mole of a structural unit represented by Formula (2); in Formula (2), two R 1 s are the same or different from each other and are each a hydrogen atom or an alkyl group having 1 to 6 carbon atoms; X is a single bond, an oxygen atom, or a group represented by —COO—, —OOC—, —CONH—, —NH—, —NHCO—, —NR 3 —, or —CH 2 O—; Y is a single bond or an oligooxyalkylene group; two R 2 s are the same or different from each other and are each an alkyl group having 1 to 6 carbon atoms; R 3 is an alkyl group having 1 to 6 carbon atoms; m is an integer of 1 to 10; and n is an integer of 2 to 10; and having a number average molecular weight of 5,000 or more has various characteristics suitable for use in contact with a living organism and can be easily produced.

The invention claimed is: 
     
       1. A compound represented by Formula (1): 
       
         
           
           
               
               
           
         
         in Formula (1), two R 1 s are the same or different from each other and are each a hydrogen atom or an alkyl group having 1 to 6 carbon atoms; substituents A are the same or different from each other and are each a substituent comprising an amino group, a hydroxy group, an epoxy group, or a (meth)acryloyl group; X is a single bond, an oxygen atom, or a group represented by —COO—, —OOC—, —CONH—, —NH—, —NHCO—, —NR 3 —, or —CH 2 O—; Y is a single bond or an oligooxyalkylene group; two R 2 s are the same or different from each other and are each an alkyl group having 1 to 6 carbon atoms; R 3  is an alkyl group having 1 to 6 carbon atoms; m is an integer of 1 to 10; and n is an integer of 2 to 10. 
       
     
     
       2. The compound according to  claim 1 , wherein each substituent A is a substituent comprising an amino group. 
     
     
       3. The compound according to  claim 1 , wherein n is an integer of 3 to 5. 
     
     
       4. A polymer comprising at least 1% by mole of a structural unit represented by Formula (2): 
       
         
           
           
               
               
           
         
         in Formula (2), two R 1 s are the same or different from each other and are each a hydrogen atom or an alkyl group having 1 to 6 carbon atoms; X is a single bond, an oxygen atom, or a group represented by —COO—, —OOC—, —CONH—, —NH—, —NHCO—, —NR 3 —, or —CH 2 O—; Y is a single bond or an oligooxyalkylene group; two R 2 s are the same or different from each other and are each an alkyl group having 1 to 6 carbon atoms; R 3  is an alkyl group having 1 to 6 carbon atoms; m is an integer of 1 to 10; and n is an integer of 2 to 10; 
         and having a number average molecular weight of 5,000 or more. 
       
     
     
       5. The polymer according to  claim 4 , wherein the polymer has a bond selected from the group consisting of an amide bond, a urethane bond, a urea bond, and an imide bond in a main chain skeleton thereof. 
     
     
       6. The polymer according to  claim 4 , comprising at least 1% by mole of the structural unit represented by Formula (2) and a structural unit comprising an isocyanate group-terminated urethane prepolymer prepared by reacting a diisocyanate compound and a diol compound, and having a number average molecular weight of 5,000 or more. 
     
     
       7. The polymer according to  claim 6 , wherein the polymer has a urethane bond and a urea bond in a main chain skeleton thereof. 
     
     
       8. The polymer according to  claim 4 , wherein n is an integer of 3 to 5. 
     
     
       9. A film, sheet, fiber, or membrane comprising the polymer according to  claim 4 . 
     
     
       10. A medical product comprising the polymer according to  claim 4 . 
     
     
       11. A method for producing the polymer according to  claim 4 , the method comprising:
 a step of subjecting a compound represented by Formula (1): 
 
       
         
           
           
               
               
           
         
         in Formula (1), two R1s are the same or different from each other and are each a hydrogen atom or an alkyl group having 1 to 6 carbon atoms; substituents A are the same or different from each other and are each a substituent comprising an amino group, a hydroxy group, an epoxy group, or a (meth)acryloyl group; X is a single bond, an oxygen atom, or a group represented by —COO—, —OOC—, —CONH—, —NH—, —NHCO—, —NR 3 —, or —CH 2 O—; Y is a single bond or an oligooxyalkylene group; two R2s are the same or different from each other and are each an alkyl group having 1 to 6 carbon atoms; R3 is an alkyl group having 1 to 6 carbon atoms; m is an integer of 1 to 10; and n is an integer of 2 to 10; 
         and an additional polymerizable monomer to polycondensation reaction, polyaddition reaction, or radical polymerization reaction or a step of reacting a polymerizable monomer comprising the compound represented by Formula (1) with a functional group-terminated prepolymer capable of reacting therewith. 
       
     
     
       12. The production method according to  claim 11 , wherein the produced polymer has a bond selected from the group consisting of an amide bond, a urethane bond, a urea bond, and an imide bond in a main chain skeleton thereof. 
     
     
       13. The production method according to  claim 11 , wherein the substituent A in Formula (1) comprises an amino group or a hydroxy group, and the functional group-terminated prepolymer capable of reacting with the compound represented by Formula (1) is an isocyanate group-terminated urethane prepolymer prepared by reacting a diisocyanate compound and a diol compound.