Unit dose aseptic aerosol misting device

Abstract

A unit dose capsule for use with a sonic generator includes a deformable membrane adapted to releasably engage the distal end of the elongate horn, a nozzle including at least one delivery opening; a nozzle including at least one delivery opening; and a reservoir containing a liquid composition disposed therebetween. When the unit dose capsule is engaged to the distal end of the elongate horn, the nozzle is disposed in an outwardly facing orientation, and the reservoir is in liquid communication with the at least one nozzle. The unit dose capsule can be included in a kit with a handheld misting device comprising a housing having a dispensing window arranged and configured to contain a sonic generator and a power source.

What is claimed is: 
     
       1. A kit comprising:
 a) a handheld misting device comprising a housing arranged and configured to contain:
 i) an ultrasonic generator comprising a converter and an elongate ultrasonic horn having a proximal end coupled to the converter and a distal end arranged and configured to extend outside of the housing; and 
 ii) a power source coupled to the ultrasonic generator; and 
 
 b) at least one unit dose capsule covered by a cap having a window, the capsule comprising:
 i) a first portion comprising a deformable membrane disposed on a first side of the unit dose capsule and adapted to cover and releasably engage the distal end of the elongate ultrasonic horn; 
 ii) a second portion comprising at least one sub-millimeter sized nozzle disposed on a second, exterior side of the unit dose capsule, the second, exterior side being opposite the first side of the unit dose capsule, to produce liquid aerosol droplets wherein when the unit dose capsule is engaged to the distal end of the elongate ultrasonic horn, the second portion of the capsule is disposed in an outwardly facing orientation adjacent the window; and 
 iii) a reservoir containing a first liquid composition in communication with the at least one nozzle; 
 
 
       whereby an aerosol mist is delivered by the nozzle through the window in the cap. 
     
     
       2. The kit of  claim 1 , wherein a plurality of unit dose capsules are operatively connected to a revolver, and the revolver is arranged and configured to index each unit dose capsule to engagement with the distal end of the elongate ultrasonic horn. 
     
     
       3. The kit of  claim 1 , wherein the housing has a receptacle disposed proximate the distal end of the elongate ultrasonic horn and is arranged and configured to releasably accommodate the unit dose capsule. 
     
     
       4. The kit of  claim 1  wherein the liquid aerosol droplets produced thereby have an equivalent diameter between 20 μm and 60 μm.