Apparatus and method for estimating glucose exposure and generating glucose exposure estimation model

Abstract

An apparatus for estimating a glucose exposure may include: a spectrometer configured to measure a plurality of Raman spectra from an object; and a processor configured to extract depth-specific protein information from the plurality of Raman spectra and estimate the glucose exposure of the object based on the depth-specific protein information.

What is claimed is: 
     
       1. An apparatus for estimating a glucose exposure, the apparatus comprising:
 a spectrometer configured to measure a plurality of Raman spectra from an object; and 
 a processor configured to extract depth-specific protein information from the plurality of Raman spectra and estimate the glucose exposure of the object based on the depth-specific protein information, 
 wherein the processor is further configured to extract a representative Raman spectrum from the plurality of Raman spectra and extract the depth-specific protein information from the representative Raman spectrum, and 
 wherein the processor is further configured to extract a Raman spectrum of a predetermined sample number from the plurality of Raman spectra as the representative Raman spectrum. 
 
     
     
       2. The apparatus of  claim 1 , wherein the spectrometer comprises:
 a light source configured to emit a light to the object; and 
 a photodetector configured to acquire the plurality of Raman spectra by receiving the light reflected or scattered from the object. 
 
     
     
       3. The apparatus of  claim 1 , wherein the spectrometer is further configured to measure the plurality of Raman spectra at a predetermined time interval for a predetermined period of time. 
     
     
       4. The apparatus of  claim 1 , wherein the processor is further configured to remove background noise from the extracted representative Raman spectrum. 
     
     
       5. The apparatus of  claim 1 , wherein the depth-specific protein information comprises intradermal collagen information and intraepidermal keratin information. 
     
     
       6. The apparatus of  claim 1 , wherein the processor is further configured to extract a first Raman peak value corresponding to intradermal collagen information and a second Raman peak value corresponding to intraepidermal keratin information from the plurality of Raman spectra, and estimate the glucose exposure of the object based on the first Raman peak value, the second Raman peak value, and a glucose exposure estimation model. 
     
     
       7. The apparatus of  claim 6 , wherein the glucose exposure estimation model defines a relationship between the glucose exposure and a ratio of the first Raman peak value to the second Raman peak value. 
     
     
       8. The apparatus of  claim 1 , wherein the processor is further configured to generate carbohydrate intake guide information based on the glucose exposure of the object. 
     
     
       9. The apparatus of  claim 8 , wherein the carbohydrate intake guide information comprises information indicating whether a daily amount of carbohydrate intake of the object is adequate. 
     
     
       10. The apparatus of  claim 8 , wherein the processor is further configured to determine a daily amount of the glucose exposure by monitoring the glucose exposure of the object, determine whether the calculated daily amount of the glucose exposure is within a predetermined threshold range, and generate the carbohydrate guide information based on a result of a determination of whether the calculated daily amount is within the predetermined threshold range.