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US11737699B2ActiveUtilityPatentIndex 73

Systems and methods for performing electrophysiology (EP) signal processing

Assignee: BIOSIG TECH INCPriority: May 9, 2018Filed: Apr 13, 2022Granted: Aug 29, 2023
Est. expiryMay 9, 2038(~11.8 yrs left)· nominal 20-yr term from priority
Inventors:DRAKULIC BUDIMIR SFAKHAR SINAFOXALL THOMAS GVLAJINIC BRANISLAVASIRVATHAM SAMUEL J
A61B 5/33A61B 5/346A61B 5/339A61B 2018/00351G16H 40/63A61B 5/725A61B 5/283A61B 18/12A61B 18/1492A61B 5/7246A61B 5/7225A61B 5/7203A61B 5/28A61B 5/7221A61B 5/7217A61B 5/318A61B 5/30A61B 5/0245A61B 5/308A61B 5/0006A61B 5/0215A61B 5/02405A61B 5/0538A61B 5/352A61B 5/361A61B 5/363A61B 5/366A61B 5/4836A61B 5/742A61B 5/7435A61B 2018/00577A61B 2562/18A61B 2562/223H01L 2924/14335H02H 9/04H02H 9/045H03F 3/45H03F 3/45475H03F 3/68H03F 2200/129H03F 2200/171H03F 2200/234H03F 2200/375H03F 2200/451H03F 2203/45116H03F 2203/45528H03F 2203/45601H03K 5/125H04L 43/02H04L 47/50H03H 2017/0298H04B 1/0014H04B 1/0039A61B 5/367A61B 5/316A61B 5/343A61B 2018/00839A61B 2018/00982
73
PatentIndex Score
0
Cited by
275
References
15
Claims

Abstract

Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
       1. A system for producing a clean unipolar signal, comprising:
 a first circuit board configured to process a first biomedical signal; and 
 a plurality of second circuit boards, each configured to process a corresponding second biomedical signal, 
 wherein the first circuit board and the plurality of second circuit boards each comprise a corresponding set of components comprising an input protection circuit, a radio frequency filter circuit, a differential signal amplification stage, and an analog-to-digital (A/D) converter organized in a corresponding processing path, wherein each of the set of components is substantially the same and each of the processing paths is substantially the same, 
 wherein the first circuit board further comprises a large-signal detection circuit coupled to the differential signal amplification stage of the first circuit board and configured to remove signal saturation from the first biomedical signal being output from the differential signal amplification stage of the first circuit board based on a time constant, wherein the time constant specifies a length of time that the first biomedical signal being output from the differential signal amplification stage of the first circuit board is at a maximum amplitude, and 
 wherein the first circuit board processes the first biomedical signal using its corresponding processing path and each second circuit board processes its corresponding second biomedical signal using its corresponding processing path. 
 
     
     
       2. The system of  claim 1 , wherein a single Wilson Central Terminal (WCT) signal is used for the first circuit board and the plurality of second circuit boards. 
     
     
       3. The system of  claim 1 , wherein the input protection circuit of the first circuit board is configured to shunt a voltage of the first biomedical signal greater than or equal to 300 V. 
     
     
       4. The system of  claim 1 , wherein the radio frequency filter circuit of the first circuit board is configured to attenuate an amplitude of the first biomedical signal between about 300 kHz and about 600 kHz. 
     
     
       5. The system of  claim 1 , wherein the first circuit board further comprises a low-frequency feedback circuit coupled to the radio frequency filter circuit of the first circuit board, wherein the low-frequency feedback circuit is configured to drive a voltage of a reference node of the radio frequency filter circuit of the first circuit board to increase input impedance of signal frequencies of the first biomedical signal such that the radio frequency filter circuit of the first circuit board is configured to act as an open circuit at the signal frequencies of the first biomedical signal. 
     
     
       6. The system of  claim 1 , wherein the first circuit board further comprises a buffer. 
     
     
       7. The system of  claim 6 , wherein the differential signal amplification stage of the first circuit board comprises an instrumentation amplifier, a first differential amplifier, and a second differential amplifier, wherein an output of the instrumentation amplifier has a differential gain of about 20, an output of the first differential amplifier has a differential gain of about 1, and an output of the second differential amplifier has a differential gain of about 0.5. 
     
     
       8. The system of  claim 7 , wherein the A/D converter of the first circuit board is coupled to an output of the second differential amplifier of the first circuit board, wherein the A/D converter of the first circuit board is configured to convert the first biomedical signal to a digital format. 
     
     
       9. A method producing a clean unipolar signal, comprising:
 processing, by a first circuit board, a first biomedical signal; and 
 processing, by a plurality of second circuit boards, a corresponding second biomedical signal, 
 wherein the first circuit board and the plurality of second circuit boards each comprise a corresponding set of components comprising an input protection circuit, a radio frequency filter circuit, a differential signal amplification stage, and an analog-to-digital (A/D) converter organized in a corresponding processing path, wherein each of the set of components is substantially the same and each of the processing paths is substantially the same, 
 wherein the first circuit board further comprises a large-signal detection circuit, 
 wherein the processing, by the first circuit board, the first biomedical signal further comprises removing, by the large-signal detection circuit of the first circuit board, signal saturation from the first biomedical signal being output from the differential signal amplification stage of the first circuit board based on a time constant, wherein the time constant specifies a length of time that the first biomedical signal being output from the differential signal amplification stage of the first circuit board is at a maximum amplitude, and 
 wherein the first circuit board processes the first biomedical signal using its corresponding processing path and each second circuit board processes its corresponding second biomedical signal using its corresponding processing path. 
 
     
     
       10. The method of  claim 9 , wherein a single Wilson Central Terminal (WCT) signal is used for the first circuit board and the plurality of second circuit boards. 
     
     
       11. The method of  claim 9 , further comprising:
 shunting, by the input protection circuit of the first circuit board, a voltage of the first biomedical signal greater than or equal to 300 V. 
 
     
     
       12. The method of  claim 9 , further comprising:
 attenuating, by the radio frequency filter circuit of the first circuit board, an amplitude of the first biomedical signal between about 300 kHz and about 600 kHz. 
 
     
     
       13. The method of  claim 12 , further comprising:
 driving, by a low-frequency feedback circuit coupled to the radio frequency filter circuit of the first circuit board, a voltage of a reference node of the radio frequency filter circuit of the first circuit board to increase input impedance of signal frequencies of the first biomedical signal such that the radio frequency filter circuit of the first circuit board is configured to act as an open circuit at the signal frequencies of the first biomedical signal. 
 
     
     
       14. The method of  claim 9 , wherein the first circuit board further comprises a buffer and the differential signal amplification stage of the first circuit board comprises an instrumentation amplifier, a first differential amplifier, and a second differential amplifier, and further comprising:
 outputting, by the instrumentation amplifier, a differential gain of about 20; 
 outputting, by the first differential amplifier, a differential gain of about 1; and 
 outputting, by the second differential amplifier, a differential gain of about 0.5. 
 
     
     
       15. The method of  claim 14 , wherein the A/D converter of the first circuit board is coupled to an output of the second differential amplifier of the first circuit board, and further comprising:
 converting, by the A/D converter of the first circuit board, the first biomedical signal to a digital format.

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