Left atrial appendage occluder

Abstract

A left atrial appendage (LAA) occluder includes a sealing portion and a fixing portion connected to the sealing portion, and one or more sealed seed sources encapsulated with radioactive particles. The sealed seed sources are arranged on the sealing portion and/or the fixing portion ( 20 ) and configured for forming an annular isolation band on an inner wall of an LAA after the radioactive particles are released. The annular isolation band is configured for blocking the electrical signal conduction between the LAA and a left atrium. In the LAA occluder, the annular isolation band is formed on the inner wall of the LAA by the release of the radioactive particles in the sealed seed sources arranged on the sealing portion and/or the fixing portion.

The invention claimed is: 
     
       1. A left atrial appendage (LAA) occluder, comprising
 a sealing portion and a fixing portion connected to the sealing portion, 
 wherein the LAA occluder further comprises one or more sealed seed sources encapsulated with radioactive particles, 
 wherein the sealing portion comprises a sealing disc and a balloon having an open end, a proximal end of the sealing disc is provided with a hollow proximal connector, the balloon is located inside the sealing disc, and the open end is sleeved at a distal end of the hollow proximal connector; 
 wherein the sealed seed sources are arranged on the sealing portion and/or the fixing portion and used to form an annular isolation band on an inner wall of an LAA after the radioactive particles are released, and the annular isolation band is used to block the electrical signal conduction between the LAA and a left atrium. 
 
     
     
       2. The LAA occluder according to  claim 1 , wherein the sealing portion or the fixing portion is provided with at least one flow blocking film on which the sealed seed sources are fixed. 
     
     
       3. The LAA occluder according to  claim 2 , wherein the sealed seed sources are evenly distributed near an edge of the flow blocking film. 
     
     
       4. The LAA occluder according to  claim 1 , wherein the fixing portion comprises a plurality of supporting rods or woven wires, which are provided with the sealed seed sources respectively. 
     
     
       5. The LAA occluder according to  claim 4 , wherein at least one supporting rod is provided with a hole-groove structure in which the sealed seed sources are fixedly placed. 
     
     
       6. The LAA occluder according to  claim 5 , wherein the sealed seed sources are arranged at a proximal end of the fixing portion. 
     
     
       7. The LAA occluder according to  claim 1 , wherein the sealed seed sources are evenly distributed in a circumferential direction of the sealing portion or the fixing portion. 
     
     
       8. The LAA occluder according to  claim 7 , wherein vertical distances from the various sealed seed sources on the sealing portion or the fixing portion to a central axis of the LAA occluder are equal. 
     
     
       9. The LAA occluder according to  claim 1 , wherein the sealed seed source is capable of being injected into the balloon through a catheter when the LAA occluder is unfolded, wherein the catheter is removably connected to the proximal connector. 
     
     
       10. The LAA occluder according to  claim 9 , wherein the proximal connector has a threaded hole, and the threaded hole is configured for a threaded connection with the catheter. 
     
     
       11. The LAA occluder according to  claim 1 , wherein the sealing disc further comprises a proximal disc surface and a distal disc surface, wherein a flow blocking membrane is arranged on the sealing disc, and the flow blocking membrane is located between the balloon and the distal disc surface.