Decarboxylated cannabis compositions and methods of making the same

Abstract

Decarboxylated cannabis compositions and methods of making and using the same are provided. The methods produce a decarboxylated product that has more terpenes and cannabidiol preserved and less oxidation of tetrahydrocannabinol to cannabinol, compared to a decarboxylated product made by a traditional decarboxylation process.

What is claimed: 
     
       1. A method for preparing a decarboxylated  cannabis  composition, comprising:
 (a) adding  cannabis  material to a reaction chamber, 
 (b) treating the reaction chamber with inert gas, 
 (c) sealing the reaction chamber, 
 (d) initiating a decarboxylation reaction of the  cannabis  material at about 70° C. to about 150° C., for about 0.5 hour to about 10 hours in the sealed reaction chamber, 
 (e) condensing within the sealed reaction chamber at about 0° C. to about 20° C., 
 (f) retaining a decarboxylated  cannabis  composition within the sealed reaction chamber, 
 (g) optionally, storing the sealed reaction chamber comprising the decarboxylated  cannabis  composition at a temperature of about −40° C. to about −20° C., and 
 (h) unsealing the sealed reaction chamber to form an unsealed reaction chamber comprising the decarboxylated  cannabis  composition, 
 wherein no or substantially no solvent is added to the reaction chamber, and 
 wherein no by-products are removed from the reaction chamber prior to the unsealing of the sealed reaction chamber. 
 
     
     
       2. The method of  claim 1 , wherein after step (h), the unsealed reaction chamber is placed in a water bath and heated to a temperature of about 50° C. to about 80° C. or 65° C. to about 75° C. 
     
     
       3. The method of  claim 1 , further comprising filling a syringe or pipette with an amount of decarboxylated  cannabis  composition,
 wherein the syringe or pipette is heated to a temperature of about 55° C. to about 75° C. or about 60° C. to about 70° C. prior to filling, and 
 wherein the filled syringed or pipette is maintained at a temperature of about 55° C. to about 75° C. or about 60° C. to about 70° C. 
 
     
     
       4. The method of  claim 3 , wherein the syringe or pipette is a borosilicate glass syringe or borosilicate glass pipette. 
     
     
       5. The method of any of  claim 3 , further comprising transferring the contents of the filled syringe or pipette into a vaporizer or vaporizer cartridge. 
     
     
       6. The method of  claim 1 , wherein after step (c), the reaction chamber remains sealed until step (h). 
     
     
       7. The method of  claim 1 , wherein the reaction chamber does not contain a filter or coils. 
     
     
       8. The method of  claim 1 , further comprising placing an amount of the decarboxylated  cannabis  composition into a vaporizer or a vaporizer cartridge. 
     
     
       9. The method of  claim 8 , wherein no solvents or additives are added to the decarboxylated  cannabis  composition prior to placing in a vaporizer or a vaporizer cartridge. 
     
     
       10. The method of  claim 9 , wherein no flavoring agents are added to the decarboxylated  cannabis  composition prior to placing in a vaporizer or a vaporizer cartridge. 
     
     
       11. The method of  claim 1 , wherein the  cannabis  material comprises a  cannabis  extract, a  cannabis  concentrate, dried or live plant matter, or a mixture thereof. 
     
     
       12. The method of  claim 1 , wherein the  cannabis  material comprises no or substantially no solvent. 
     
     
       13. The method of  claim 1 , wherein the inert gas comprises nitrogen or argon gas. 
     
     
       14. The method of  claim 1 , wherein the reaction chamber is a glass vessel. 
     
     
       15. The method of  claim 1 , wherein step (d) occurs at about 90° C. to about 130° C. or about 110° C. to about 125° C. 
     
     
       16. The method of  claim 1 , wherein step (d) occurs for about 1 to about 5 hours or about 2 to about 3 hours. 
     
     
       17. The method of  claim 1 , wherein the decarboxylated  cannabis  composition comprises no additives and substantially no tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), or cannabigerolic acid (CBGA). 
     
     
       18. The method of  claim 1 , further comprising (g) storing the sealed reaction chamber comprising the decarboxylated cannabis composition at a temperature of about −40° C. to about −20° C. 
     
     
       19. The method of  claim 18 , wherein after step (g), the sealed reaction chamber is placed in a water bath and heated to a temperature of about 50° C. to about 80° C. or about 65° C. to about 75° C. 
     
     
       20. The method of  claim 3 , wherein the syringe or pipette is made from glass, porcelain, or steel.