US12102415B2ActiveUtilityA1
Systems and methods to improve management and monitoring of cardiovascular disease
Est. expiryNov 7, 2039(~13.3 yrs left)· nominal 20-yr term from priority
A61B 5/7278G16H 40/67G16H 50/30A61B 8/5261A61B 8/5223A61B 8/065A61B 5/0002A61B 8/0883A61B 5/029A61B 5/024A61B 5/021A61B 5/02028A61B 5/02007G16H 50/50G16H 10/60
52
PatentIndex Score
0
Cited by
80
References
16
Claims
Abstract
The present invention is directed to systems and methods for identifying a cardiovascular disease of a patient. In one embodiment, the method includes obtaining measurements for a diastolic pressure, a systolic pressure, a heartbeat period, a stroke volume, and an ejection period for the patient, and then determining an aortic compliance for the patient based on these measurements. The diastolic pressure, systolic pressure, and heartbeat period are each measured directly from the patient, and the stroke volume and ejection period are each measured from echocardiogram data. In another embodiment, the method includes obtaining measurements for a diastolic pressure and a systolic pressure for the patient, obtaining an estimate of a stroke volume for the patient, and then determining an aortic compliance for the patient based on the diastolic pressure, the systolic pressure, and the stroke volume. These methods may be implemented using a computing device that optionally accesses an electronic medical record to retrieve the relevant parameters.
Claims
exact text as granted — not AI-modifiedWhat is claimed and desired to be secured by Letters Patent is as follows:
1. A method for identifying a cardiovascular disease of a patient, comprising:
measuring a diastolic pressure for the patient;
measuring a systolic pressure for the patient;
measuring a heartbeat period for the patient;
measuring a stroke volume for the patient;
measuring an ejection period for the patient; and
determining an aortic compliance for the patient based on the following equation:
C
=
Δ
V
P
d
T
-
T
e
T
1
ln
(
P
s
/
P
d
)
1
-
(
P
s
/
P
d
)
T
e
T
-
T
e
1
-
(
P
s
/
P
d
)
T
e
T
-
T
e
where Pd is the diastolic pressure for the patient, Ps is the systolic pressure for the patient, Tis the heartbeat period for the patient, ΔV is the stroke volume for the patient, and Te is the ejection period for the patient.
2. The method of claim 1 , wherein the diastolic pressure, the systolic pressure, and the heartbeat period are each measured directly from the patient.
3. The method of claim 1 , wherein the stroke volume and the ejection period are each determined based on echocardiogram data for the patient.
4. The method of claim 1 , further comprising determining a peripheral resistance for the patient based on the diastolic pressure, the systolic pressure, the heartbeat period, the stroke volume, and the ejection period.
5. The method of claim 4 , wherein the peripheral resistance is determined based on the following equation:
R
=
P
d
T
e
Δ
V
1
-
(
P
s
/
P
d
)
T
T
-
T
e
1
-
(
P
s
/
P
d
)
T
e
T
-
T
e
where P d is the diastolic pressure for the patient, P s is the systolic pressure for the patient, Tis the heartbeat period for the patient, ΔV is the stroke volume for the patient, and Te is the ejection period for the patient.
6. A method for identifying a cardiovascular disease of a patient, comprising:
measuring a diastolic pressure for the patient;
measuring a systolic pressure for the patient;
measuring a stroke volume for the patient; and
determining an aortic compliance for the patient based on the following equation:
C
=
Δ
V
P
s
+
P
d
+
P
s
P
d
2
ln
(
P
s
/
P
d
)
where Pd is the diastolic pressure for the patient, Ps is the systolic pressure for the patient, and ΔV is the stroke volume for the patient.
7. The method of claim 6 , wherein the stroke volume comprises a previous stroke volume measurement of the patient.
8. The method of claim 7 , further comprising:
measuring a heartbeat period for the patient; and
determining a peripheral resistance for the patient based on the diastolic pressure, the systolic pressure, the heartbeat period, and the stroke volume.
9. The method of claim 8 , wherein the peripheral resistance is determined based on the following equation:
R
=
P
s
+
P
d
+
P
s
P
d
3
T
Δ
V
where P d is the diastolic pressure for the patient, P s is the systolic pressure for the patient, T is the heartbeat period for the patient, and ΔV is the stroke volume for the patient.
10. A method for identifying a cardiovascular disease of a patient comprising:
measuring a diastolic pressure for the patient;
measuring a systolic pressure for the patient;
measuring a heartbeat period for the patient;
measuring a stroke volume for the patient;
measuring an ejection period for the patient;
using a computing device to:
determine an aortic compliance for the patient based on the following equation:
C
=
Δ
V
P
d
T
-
T
e
T
1
ln
(
P
s
/
P
d
)
1
-
(
P
s
/
P
d
)
T
e
T
-
T
e
1
-
(
P
s
/
P
d
)
T
T
-
T
e
where Pd is the diastolic pressure for the patient, Ps is the systolic pressure for the patient, Tis the heartbeat period for the patient, ΔV is the stroke volume for the patient, and Te is the ejection period for the patient; and
cause the aortic compliance to be presented via a user interface to enable identification of the cardiovascular disease of the patient.
11. The method of claim 10 , wherein the computing device is further used to determine a peripheral resistance for the patient based on the diastolic pressure, the systolic pressure, the heartbeat period, the stroke volume, and the ejection period.
12. The method of claim 11 , wherein the peripheral resistance is determined based on the following equation:
R
=
P
d
T
e
Δ
V
1
-
(
P
s
/
P
d
)
T
T
-
T
e
1
-
(
P
s
/
P
d
)
T
e
T
-
T
e
where P d is the diastolic pressure for the patient, P s is the systolic pressure for the patient, T is the heartbeat with for the patient, ΔV is the stroke volume for the patient, and Te is the ejection period for the patient.
13. A method for identifying a cardiovascular disease of a patient, comprising:
measuring a diastolic pressure for the patient;
measuring a systolic pressure for the patient;
measuring a stroke volume for the patient;
using a computing device to:
determine an aortic compliance for the patient based on the following equation:
C
=
Δ
V
P
s
+
P
d
+
P
s
P
d
2
ln
(
P
s
/
P
d
)
where Pd is the diastolic pressure for the patient, Ps is the systolic pressure for the patient, and ΔV is the stroke volume for the patient; and
cause the aortic compliance to be presented via a user interface to enable identification of the cardiovascular disease of the patient.
14. The method of claim 13 , wherein the stroke volume comprises a previous stroke volume measurement of the patient.
15. The method of claim 13 , further comprising:
obtaining a heartbeat period associated with the patient;
using the computing device to:
determine a peripheral resistance for the patient based on the diastolic pressure, the systolic pressure, the heartbeat period, and the stroke volume; and
cause the peripheral resistance to be presented via the user interface.
16. The method of claim 15 , wherein the peripheral resistance is determined based on the following equation:
R
=
P
s
+
P
d
+
P
s
P
d
3
T
Δ
V
where P d is the diastolic pressure for the patient, P s is the systolic pressure for the patient, T is the heartbeat period for the patient, and ΔV is the stroke volume for the patient.Cited by (0)
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