US12331333B2ActiveUtilityA1
Enhancers of neurolysin activity
Est. expiryAug 31, 2038(~12.1 yrs left)· nominal 20-yr term from priority
C12Y 304/24016C07K 5/06147C12N 9/6489A61K 38/00C12N 9/6416C12P 21/06
47
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Cited by
84
References
5
Claims
Abstract
The present invention includes a composition and method of allosterically potentiating the activity of neurolysin comprising contacting the neurolysin with an amount of a histidine-containing dipeptide that is an allosteric that increases the activity of neurolysin.
Claims
exact text as granted — not AI-modifiedWhat is claimed is:
1. An allosteric activator of neurolysin selected from at least one of:
salts, or enantiomers thereof.
2. The activator of claim 1 , wherein the inhibitor is adapted for oral, intraperitoneal, intradermal, subcutaneous, intravenous, enteral, parental, or pulmonary administration.
3. The activator of claim 1 , wherein the inhibitor is combined with one or more excipients, buffers, fillers, or detergents.
4. The activator of claim 1 , wherein the inhibitor is adapted for at least one of immediate release, delayed release, or prolonged release.
5. The activator of claim 1 , wherein the activator comprises a single enantiomer.Cited by (0)
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