Process and system with a measuring device and an analysis device for processing data

Abstract

An apparatus and process ( 100 ) for processing data ( 101, 102, 103 ) obtained by an imaging technique enables an improvement of a determination of quality and quantity of ventilation of the lungs. By including a correction data set KDS determined during one or more inhalation phases, it is determined which effects result from adjustments of pressure levels (PEEP A , PEEP B ) ( 81, 82 ) during ventilation. The result of the determination is provided as an output signal ( 900 ).

What is claimed is: 
     
       1. A system for use during a ventilation by a ventilation device to process data obtained by means of an analysis device suitable for determining a lung condition and to process measurement data obtained by a measuring device suitable for a metrological acquisition of physical measurement data, the system comprising:
 a data input unit configured to acquire measuring device data or to receive measuring device data of the measuring device, which measuring device data are assignable to situations with predetermined pressure levels to provide the measuring device data as a first data set of measurement data over a time course of an observation period during a ventilation of a living being and the data input unit being configured to acquire data or to receive data from the analysis device which can be assigned to a first situation to provide the data as a second set of data over a time course of the observation period during ventilation of a living being, and data input unit being configured unit to acquire further data or receive further data from the analysis device which can be assigned to a second situation, in order to provide the further data as a third data set over a time course of at least one location over the observation period during ventilation of a living being; 
 a data output unit; and 
 a control unit configured to: 
 provide a control signal by interaction between the control unit and the data output unit; 
 initiate an adjustment by a predetermined pressure difference from a first positive end expiratory pressure level to a second positive end expiratory pressure level at the ventilation device by means of the control signal; 
 process the first data set, the second data set and the third data set to determine, by a comparison, a difference between the further data of the second situation and the data of the first situation; 
 include in the comparison a correction data set for a correction of the difference, the correction data set comprising data elements of the second data set which indicates specific pressure situations at times t1, t2 within the observation period, determine, based on the comparison and the difference or based on the corrected difference, an output signal which indicates the difference and/or the corrected difference; and 
 provide the output signal with the data output unit. 
 
     
     
       2. A system according to  claim 1 , wherein the second data set comprises data elements which indicate certain pressure situations at times t1, t2 as to a rising slope of an inspiratory ventilation pressure and/or a falling slope of an expiratory ventilation pressure. 
     
     
       3. A system according to  claim 1 , wherein the analysis device is configured and adapted for imaging the lungs of a living being. 
     
     
       4. A system according to  claim 3 , wherein the analysis device is configured as at least one of:
 a device configured to image the lungs of a living being for electrical impedance tomography or an EIT system; 
 a device configured to image the lungs of a living being for magnetic resonance tomography; 
 a computer tomography device configured to image the lungs of a living being; 
 an apparatus for ultrasound imaging of the lungs of a living organism. 
 
     
     
       5. A system according to  claim 1 , wherein the analysis device is configured to determine a volume of the lungs of a living being. 
     
     
       6. A system according to  claim 1 , wherein:
 the first situation is assignable to a first predetermined pressure level: 
 an adjustment of a first positive end-expiratory pressure level based on the control signal to a second positive end-expiratory pressure level by a predetermined pressure difference is initiated as an increase by the predetermined pressure difference at the level of the predetermined pressure level at the ventilation device; 
 the control unit is configured to perform said comparison as a subtraction (Z y −Z 1 ) of the third data from the second data; 
 the control unit is configured to perform said correction as a subtractive correction based on a correction (Z K1 ) to determine a corrected difference (DZK 1 ), with DZK 1 =(Z y −Z 1 )−Z K1 . 
 
     
     
       7. A system according to  claim 1 , wherein:
 the second situation is assignable to a second predetermined pressure level; 
 an adjustment of a first positive end-expiratory pressure level based on the control signal to a third positive end-expiratory pressure level by a predetermined pressure difference is initiated as a reduction by the predetermined pressure difference at the level of the predetermined pressure level at a ventilation device; 
 the control unit is configured to perform the comparison as a subtraction (Z y −Z 2 ) of the third data set from the second data set; 
 the control unit is configured to perform said correction as an additive correction based on a correction (Z K2 ) to determine a corrected difference (DZK 2 ), with DZK 2 =(Z y −Z 2 )+Z K2 . 
 
     
     
       8. A system according to  claim 6 , wherein the control unit is adapted to perform during the first situation the data acquisition at the predetermined pressure level while performing the ventilation. 
     
     
       9. A system according to  claim 7 , wherein the control unit is adapted to perform the data acquisition during the second situation at the predetermined pressure level while performing the ventilation. 
     
     
       10. A system according to  claim 6 , wherein the control unit is adapted to perform the data acquisition during the first situation at the predetermined pressure level on a plateau of the inspiratory ventilation pressure temporally after a rising slope of the inspiratory ventilation pressure. 
     
     
       11. A system according to  claim 7 , wherein the control unit is adapted to perform the data acquisition during the second situation at the predetermined pressure level on a plateau of the inspiratory ventilation pressure temporally after a rising slope of the inspiratory ventilation pressure. 
     
     
       12. A system according to  claim 1 , wherein the measuring device is adapted to carry out at least one of:
 a pressure measurement; 
 a flow measurement; and 
 a volume measurement. 
 
     
     
       13. A system according to  claim 1 , wherein the control unit is configured to perform the data acquisition as an acquisition of impedance values of selected or representative areas of the lungs and/or as an acquisition of global impedance values over time as a global impedance curve. 
     
     
       14. A system according to  claim 1 , wherein the control unit is configured to:
 determine a representative reference value or a fourth data set of reference values as a normalization data set by means of a further data acquisition in a normalization situation temporally before the first situation; and 
 to carry out normalization during data acquisition based on the normalization data set and/or based on the representative reference value. 
 
     
     
       15. A system according to  claim 1 , wherein the control unit is configured to perform a data adjustment to compensate for time differences between the first data set and the second data set to synchronize the measuring device and the analyzing device in time. 
     
     
       16. A system according to  claim 1 , wherein the control unit is configured to perform a start of data acquisition during the second situation after a time delay. 
     
     
       17. A system according to  claim 16 , wherein the control unit is configured to perform the data acquisition during the second situation in a predetermined time interval of 5 to 10 breathing cycles after initiation of the second situation with increase to a second positive end-expiratory pressure level. 
     
     
       18. A system according to  claim 16 , wherein the control unit is configured to perform the data acquisition during the second situation in a predetermined time interval of 5 to 10 breathing cycles after initiation of the second situation with lowering to a second positive end-expiratory pressure level. 
     
     
       19. A system according to  claim 1 , wherein the control unit is configured to initiate a maneuver with a substantially constant pressure level with the first situation on the ventilation device in the course of ventilation. 
     
     
       20. A system according to  claim 1 , wherein the control unit is adapted, during the performance of ventilation, to initiate a maneuver at the ventilation device with a plurality of discretely formed pressure levels on a rising slope of the inspiratory ventilation pressure. 
     
     
       21. A system according to  claim 1 , wherein the measuring device is formed as a module or as a component of the ventilation device. 
     
     
       22. A system according to  claim 1 , wherein the system is provided in combination with the analyzing device, the measuring device and the ventilating device to form a common living being ventilating and monitoring system. 
     
     
       23. A system according to  claim 22 , wherein the control unit is a component or submodule in one or more of the ventilation device, the analysis device and the measuring device and is formed as a component or module of the common system. 
     
     
       24. A system according to  claim 22 , wherein the control unit is configured to initiate maneuvers with multiple pressure levels of inspiratory ventilation pressure at the ventilation device during the performance of ventilation. 
     
     
       25. A system according to  claim 22 , wherein the control unit is adapted, in a procedure or maneuver for weaning a living being from ventilation with a pressure reduction of inspiratory ventilation pressure and/or expiratory ventilation pressure and/or end expiratory pressure by the ventilation device to initiate, coordinate or control the steps or stages of pressure reduction by means of the control signal at a level of the stages of pressure reduction or a time interval between steps of pressure reduction based on the difference. 
     
     
       26. A system according to  claim 22 , wherein the control unit is configured to initiate a maneuver with a predetermined slower inspiratory pressure increase prior to or with the first situation on the ventilation device in the course of ventilation. 
     
     
       27. A system according to  claim 22 , wherein the control unit is configured to initiate an increase of the sampling rate during data acquisition at the beginning of the first situation at the measuring device and/or at the analysis device. 
     
     
       28. A process for processing data, the process comprising the steps of:
 receiving measurement data which can be assigned to situations with predetermined pressure levels; 
 providing the measurement data as a first data set; 
 receiving electroimpedance tomography (EIT) data in a first situation; 
 providing the EIT data as a second data set; 
 receiving further EIT data in a second situation; 
 providing the further EIT data as a third data set; 
 processing the first data set, the second data set and the third data set to determine a difference between the further EIT data of the second situation and the EIT data of the first situation by means of a comparison including a correction data set; and 
 providing an output signal indicating the difference and/or a corrected difference.