Medical devices and methods

Abstract

Methods and devices to monitor an analyte in body fluid are provided. Embodiments include continuous or discrete acquisition of analyte related data from a transcutaneously positioned in vivo analyte sensor automatically or upon request from a user. The in vivo analyte sensor is coupled to an electronics unit holding a memory with instruction to cause processing circuitry to initiate a predetermined time period that is longer than a predetermined life of the sensor, during the predetermined time period, convert signals from the sensor related to glucose to respective corresponding glucose levels, without relying on any post-manufacture independent analyte measurements from a reference device, and at the expiration of the predetermined time period, disable, deactivate, or cease use of one or more feature.

What is claimed is: 
     
         1 . A printed circuit board disposed within an on-body electronics unit of a glucose monitoring system, the on-body electronics unit configured to be secured on a skin surface of a user, the printed circuit board comprising:
 a first side having an application-specific integrated circuit (ASIC) affixed thereto, the ASIC positioned proximate an insertion needle hole of the printed circuit board;   a second side having a temperature sensor affixed thereto and a proximal portion of an electrochemical glucose sensor electrically affixed thereto via a fixed electrical coupling during manufacturing, wherein the electrochemical glucose sensor has a distal portion which extends at an angle of at least 80 degrees from the second side of the printed circuit board, the distal portion configured to maintain fluid contact with an interstitial fluid under a skin layer of the user;   a multiple-loop antenna electrically coupled to the ASIC, the multiple-loop antenna comprising a first portion and a second portion, the first portion having a conductive trace disposed between the first side and the second side of the printed circuit board and wound along a first section of the printed circuit board, and the second portion disposed on a second section of the printed circuit board,   wherein the first section of the printed circuit board comprises a part of an outer periphery of the printed circuit board, and wherein the second section of the printed circuit board is different from the first section; and   a battery electrically coupled to the printed circuit board proximate the outer periphery of the printed circuit board.   
     
     
         2 . The printed circuit board of  claim 1 , wherein the second portion of the multiple-loop antenna extends away from the outer periphery and across the printed circuit board. 
     
     
         3 . The printed circuit board of  claim 1 , wherein the multiple-loop antenna is electrically coupled to the ASIC on at least one of the first side or the second side of the printed circuit board. 
     
     
         4 . The printed circuit board of  claim 1 , wherein the distal portion of the electrochemical glucose sensor extends downwards from the second side of the printed circuit board, and wherein the electrochemical glucose sensor bends to define an angle of at least 80 degrees between the proximal portion and the distal portion. 
     
     
         5 . The printed circuit board of  claim 4 , wherein the proximal portion of the electrochemical glucose sensor extends parallel to the second side of the printed circuit board. 
     
     
         6 . The printed circuit board of  claim 1 , wherein the distal portion extends at an angle of approximately 90 degrees from the second side of the printed circuit board. 
     
     
         7 . The printed circuit board of  claim 1 , wherein the distal portion extends at an angle between 80 to 90 degrees from the second side of the printed circuit board. 
     
     
         8 . The printed circuit board of  claim 1 , wherein the conductive trace is disposed on a substrate of the printed circuit board. 
     
     
         9 . The printed circuit board of  claim 1 , wherein the conductive trace comprises a copper trace. 
     
     
         10 . The printed circuit board of  claim 1 , wherein the on-body electronics unit is configured to be disabled after a predetermined useful life of the electrochemical glucose sensor.