US2002065395A1PendingUtilityA1

Novel compounds

46
Priority: Jun 20, 1997Filed: Mar 6, 2001Published: May 30, 2002
Est. expiryJun 20, 2017(expired)· nominal 20-yr term from priority
Inventors:Nicola Gail Wallis
A61P 37/02A61P 43/00A61P 31/00C07K 14/3156A61P 27/16A61P 31/04A61P 27/00A61P 27/02A61K 39/00
46
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Claims

Abstract

The invention provides response regulator polypeptides and DNA (RNA) encoding response regulator polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing response regulator polypeptides to screen for antibacterial compounds.

Claims

exact text as granted — not AI-modified
What is claimed is:  
     
         1 . An isolated polypeptide comprising a fragment of SEQ ID NO:2 comprising at least 50 consecutive amino acids of SEQ ID NO2; wherein said fragment has response regulator activity.  
     
     
         2 . A composition comprising the isolated polypeptide of  claim 1  and a carrier.  
     
     
         3 . The isolated polypeptide of  claim 1 , wherein the isolated polypeptide comprises a heterologous amino acid sequence fused to the at least 50 consecutive amino acids of SEQ ID NO:2.  
     
     
         4 . A composition comprising the isolated polypeptide of  claim 3  and a carrier.  
     
     
         5 . An isolated polypeptide comprising a fragment of SEQ ID NO:2 comprising at least 30 consecutive amino acids of SEQ ID NO:2; wherein said fragment has response regulator activity.  
     
     
         6 . A composition comprising the isolated polypeptide of  claim 5  and a carrier.  
     
     
         7 . The isolated polypeptide of  claim 5 , wherein the isolated polypeptide comprises a heterologous amino acid sequence fused to the at least 30 consecutive amino acids of SEQ ID NO:2.  
     
     
         8 . A composition comprising the isolated polypeptide of  claim 7  and a carrier.  
     
     
         9 . An isolated polypeptide comprising a fragment of SEQ ID NO:2 comprising at least 50 consecutive amino acids of SEQ ID NO:2; wherein said fragment has the ability to generate antibodies to SEQ ID NO:2.  
     
     
         10 . A composition comprising the isolated polypeptide of  claim 9  and a carrier.  
     
     
         11 . The isolated polypeptide of  claim 9 , wherein the isolated polypeptide comprises a heterologous amino acid sequence fused to the at least 50 consecutive amino acids of SEQ ID NO:2.  
     
     
         12 . A composition comprising the isolated polypeptide of  claim 11  and a carrier.  
     
     
         13 . An isolated polypeptide comprising a fragment of SEQ ID NO:2 comprising at least 30 consecutive amino acids of SEQ ID NO:2; wherein said fragment has the ability to generate antibodies to SEQ ID NO:2.  
     
     
         14 . A composition comprising the isolated polypeptide of  claim 13  and a carrier.  
     
     
         15 . The isolated polypeptide of  claim 13 , wherein the isolated polypeptide comprises a heterologous amino acid sequence fused to the at least 30 consecutive amino acids of SEQ ID NO:2.  
     
     
         16 . A composition comprising the isolated polypeptide of  claim 15  and a carrier.

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