US2002086367A1PendingUtilityA1
Novel secreted proteins
Priority: Jun 30, 2000Filed: Jun 29, 2001Published: Jul 4, 2002
Est. expiryJun 30, 2020(expired)· nominal 20-yr term from priority
C07K 2319/00C07K 14/52C07K 14/47
59
PatentIndex Score
0
Cited by
0
References
0
Claims
Abstract
The present invention provides to polynucleotides and secreted proteins encoded by the polynucleotides. The proteins include and cytokines, growth factors, include fusion proteins operably linked to a second polypeptide. The invention further provides therapeutic and diagnostic methods utilizing the polynucleotides, polypeptides, and antagonists of the polypeptides.
Claims
exact text as granted — not AI-modifiedWe claim:
1 . An isolated polypeptide comprising residues 23 to 150 as shown in SEQ ID NO:2.
2 . The isolated polypeptide of claim 1 wherein the polypeptide further comprises residues 1 to 150 as shown in SEQ ID NO:2.
3 . An isolated polynucleotide comprising a sequence of nucleotides, wherein the sequence encodes the isolated polypeptide of claim 1 .
4 . An expression vector comprising the following operably linked elements:
a transcription promoter; a DNA segment having the isolated polynucleotide of claim 3 ; and a transcription terminator.
5 . A cultured cell comprising the expression vector of claim 4 .
6 . A method of producing a polypeptide comprising culturing the cell of claim 5 under conditions whereby said sequence of nucleotides is expressed, and recovering said polypeptide.
7 . A polypeptide produced by the method of claim 6 .
8 . An isolated polynucleotide comprising the polynucleotide sequence as shown in SEQ ID NO:1.
9 . An antibody that specifically binds to the isolated protein of claim 1 .
10 . An isolated polypeptide comprising residues 19 to 117 as shown in SEQ ID NO:5.
11 . The isolated polypeptide of claim 10 wherein the polypeptide further comprises residues 1 to 117 as shown in SEQ ID NO:5.
12 . An isolated polynucleotide comprising a sequence of nucleotides, wherein the sequence encodes the isolated polypeptide of claim 10 .
13 . An expression vector comprising the following operably linked elements:
a transcription promoter; a DNA segment having the isolated polynucleotide of claim 12 ; and a transcription terminator.
14 . A cultured cell comprising the expression vector of claim 13 .
15 . A method of producing a polypeptide comprising culturing the cell of claim 14 under conditions whereby said sequence of nucleotides is expressed, and recovering said polypeptide.
16 . A polypeptide produced by the method of claim 15
17 . An isolated polynucleotide comprising the polynucleotide sequence as shown in SEQ ID NO:4.
18 . An antibody that specifically binds to the isolated protein of claim 10 .
19 . An isolated polypeptide comprising residues 20 to 185 as shown in SEQ ID NO:8.
20 . The isolated polypeptide of claim 19 wherein the polypeptide further comprises residues 1 to 185 as shown in SEQ ID NO:8.
21 . An isolated polynucleotide comprising a sequence of nucleotides, wherein the sequence encodes the isolated polypeptide of claim 19 .
22 . An expression vector comprising the following operably linked elements:
a transcription promoter; a DNA segment having the isolated polynucleotide of claim 21 ; and a transcription terminator.
23 . A cultured cell comprising the expression vector of claim 22 .
24 . A method of producing a polypeptide comprising culturing the cell of claim 23 under conditions whereby said sequence of nucleotides is expressed, and recovering said polypeptide.
25 . A polypeptide produced by the method of claim 24 .
26 . An isolated polynucleotide comprising the polynucleotide sequence as shown in SEQ ID NO:7.
27 . An antibody that specifically binds to the isolated protein of claim 19 .Join the waitlist — get patent alerts
Track US2002086367A1 — get alerts on status changes and closely related new filings.
We store only your email — no account needed. See our privacy policy.