Capillary array and capillary array photodetector

Abstract

A multi-focus capillary array that can reduce crosstalk and a capillary array photodetector are provided. On a substrate 20 on which a plurality of capillaries are aligned, a perforation 72 is formed in at least a part of an area in the rear of the capillaries when the capillary array is viewed from the photodetector.

What is claimed is:  
     
         1 . A capillary array comprising a substrate having a planar capillary holding surface and a plurality of capillaries aligned on the capillary holding surface of the substrate, wherein a laser beam irradiated on a capillary at one end or capillaries at both ends of the plurality of capillaries in a substantially parallel direction with respect to the capillary holding surface propagates to all the plurality of capillaries one by one to travel through the capillaries, and emissions from each of the capillaries are detected in a substantially perpendicular direction with respect to the capillary holding surface, 
 wherein the substrate is provided with a through hole extending from the capillary holding surface to a back side of the substrate in an area opposing to portions of the plurality of capillaries each of which receives the laser beam irradiation.    
     
     
         2 . A capillary array comprising a substrate having a planar capillary holding surface and a plurality of capillaries aligned on the capillary holding surface of the substrate, wherein a laser beam irradiated on a capillary at one end or capillaries at both ends of the plurality of capillaries in a substantially parallel direction with respect to the capillary holding surface propagates to all the plurality of capillaries one by one to travel through the capillaries, and emissions from each of the capillaries are detected in a substantially perpendicular direction with respect to the capillary holding surface, 
 wherein the capillary holding surface of the substrate opposing to portions of the plurality of capillaries each of which receives the laser beam irradiation is subjected to a light-scattering prevention treatment or a light-reflection prevention treatment.    
     
     
         3 . A capillary array comprising a substrate having a planar capillary holding surface, a plurality of capillaries aligned on the capillary holding surface of the substrate, scattered light shielding means placed on the plurality of capillaries for shielding areas at which capillaries contact with each other with a partial area including are adjacent to one another with partial areas including a central axis of each of the capillaries being not shielded, wherein a laser beam irradiated on a capillary at one end or capillaries at both ends of the plurality of capillaries in a substantially parallel direction with respect to the capillary holding surface propagates to all the plurality of capillaries one by one to travel through the capillaries, and emissions from each of the capillaries are detected through the space between the shielding means in a substantially perpendicular direction with respect to the capillary holding surface, wherein each of the capillaries is provided with a coating, but is not provided with the coating in an area for receiving the laser beam irradiation thereon, and the scattered light shielding means contacts with the area of the capillaries for which the coating is not provided.  
     
     
         4 . A capillary array photodetector comprising a reference surface which contacts with a capillary holding surface of a capillary array holding substrate that holds a capillary array, fixing means for fixing the capillary array holding substrate brought into contact with the reference surface by pressing the capillary array holding substrate from the rear surface thereof, a laser light source, an irradiation optical system for setting a part of a light path extending from the light source to be substantially parallel to the capillary holding surface of the capillary array holding substrate contacting with the reference surface, and a photodetector system for detecting emissions, 
 the capillary array photodetector detecting emissions from each of the capillaries, which emissions being caused by laser beam that is irradiated from the irradiation optical system on a capillary at one end or capillaries at both ends of the plurality of capillaries aligned on the capillary holding surface of the capillary array holding substrate fixed on the reference surface with being brought into contact therewith and that propagates to all the plurality of capillaries one by one to travel through the capillaries,    wherein the fixing means is provided with a recessed portion opening on a side of the reference surface.    
     
     
         5 . The capillary array photodetector according to  claim 4 , wherein a surface of the recessed portion of the fixing means is subjected to a light-scattering prevention treatment or a light-reflection prevention treatment.