US2003026807A1PendingUtilityA1

Immuno-potentiating systems for preparation of immunogenic materials

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Priority: Jun 23, 1987Filed: Dec 2, 1997Published: Feb 6, 2003
Est. expiryJun 23, 2007(expired)· nominal 20-yr term from priority
Inventors:George H. Lowell
A61K 39/21A61K 39/385A61K 39/008A61K 2039/6031C12N 2740/16134A61K 2039/6068A61K 39/005A61K 39/12A61K 2039/6018A61K 2039/55505A61K 39/015A61K 2039/55555A61K 2039/545Y02A50/30
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Claims

Abstract

The invention is directed to improved immunopotentiating systems for preparation of immunogenic materials. More particularly, the invention is directed to immunogenic compositions containing a protein, polypeptide, or peptide, a hydrophobic anchor, and a proteosome. The immunogenic compositions are suitable for use as therapeutic agents and vaccines.

Claims

exact text as granted — not AI-modified
1 . A construct comprising gp160 and a proteosome.  
     
     
         2 . A composition of matter comprising a vaccine which contains as an active agent a construct of  claim 1  in a pharmaceutically acceptable carrier.  
     
     
         3 . A composition of  claim 2  containing an adjuvant.  
     
     
         4 . A composition of  claim 3  wherein the adjuvant is alum.

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