Anti-inflammation analgesic preparation

Abstract

The present invention is concerned with an anti-inflammation analgesic preparation which contains a specific 3-0-substituted ascorbic acid as an active ingredient, shows excellent anti-inflammation analgesic effects and is excellent in shelf life, safety to a skin and endermic absorptivity of the active ingredient.

1 . (Deleted)  
     
     
         2 . (Amended) An anti-inflammation analgesic preparation comprising a 3-O-substituted ascorbic acid of the formula (II),  
       
         
           
           
               
               
           
         
         wherein R 1  is a linear or branched alkyl group having 1 to 20 carbon atoms, an alkylcarbonylmethyl or an alkoxycarbonyl methyl, or a salt thereof.  
       
     
     
         3 . (Amended) The anti-inflammation analgesic preparation of  claim 2 , which further comprises at least one selected from a salicylic acid derivative, indomethacin, piroxicam,-flurbiprofen, felbinac, ketoprofen, menthol, camphor, thymol, crotamiton or eucalyptus oil.  
     
     
         4 . (Amended) The anti-inflammation analgesic preparation of any one of claims  2  and  3 , which is for application to an external skin.