Preventives and/or remedies for hyperphosphatemia

Abstract

Provided in a phosphate ion adsorbent containing a weakly basic anion exchange resin as an active ingredient which aims at providing preventives and/or remedies for hyperphosphatemia having a high selectivity for the adsorption of phosphate ion and showing an effect of lowering blood phosphorus level and another effect of suppressing phosphorus excretion into the urine.

1 . A phosphate ion adsorbent comprising as an active ingredient a weakly basic anion exchange resin.  
     
     
         2 . The phosphate ion adsorbent according to  claim 1 , characterized in that the weakly basic anion exchange resin is a copolymer containing as monomer components an acrylic acid type compound having a tertiary amino group and divinylbenzene.  
     
     
         3 . The phosphate ion adsorbent according to  claim 2 , characterized in that the copolymer further contains as monomer components one or more components selected from the group consisting of acrylonitrile, vinylimidazole, vinylhistidine, vinylpyrazine and diaminodiphenylmethane.  
     
     
         4 . The phosphate ion adsorbent according to any one of claims  1 - 3 , characterized in that the weakly basic anion exchange resin has porous bead structure.  
     
     
         5 . The phosphate ion adsorbent according to  claim 4 , characterized in that the weakly basic anion exchange resin is Ionac A-365 (trade name; Sybron Chemicals Co.).  
     
     
         6 . A preventive and/or a remedy for hyperphosphatemia, characterized in that it contains the phosphate ion adsorbent according to any one of claims  1 - 5 .