US2003093831A1PendingUtilityA1

Methods of using viral replicase polynucleotides and polypeptides

Assignee: PIONEER HI BRED INTPriority: Feb 25, 1999Filed: Aug 8, 2002Published: May 15, 2003
Est. expiryFeb 25, 2019(expired)· nominal 20-yr term from priority
C12N 15/8209C12N 15/8261C12N 15/8201C12N 15/8207Y02A40/146
57
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Claims

Abstract

The invention provides novel methods of using viral replicase polypeptides. Included are methods for increasing transformation frequencies, providing a positive growth advantage, and modulating cell division.

Claims

exact text as granted — not AI-modified
What is claimed is:  
     
         1 . A method for increasing transformation frequencies in a target plant cell comprising introducing into the target plant cell an isolated plant geminivirus replicase polypeptide.  
     
     
         2 . The method of  claim 2  wherein the geminivirus replicase polypeptide is wheat dwarf virus Replicase.  
     
     
         3 . The method of  claim 3  wherein the geminivirus replicase polypeptide is RepA.  
     
     
         4 . The method of  claim 1  further comprising introducing into the target plant cell a polynucleotide of interest.  
     
     
         5 . The method of  claim 4  wherein the plant cell is from a monocot or a dicot plant.  
     
     
         6 . The method of  claim 5  wherein the plant cell is from corn, soybean, sunflower, sorghum, canola, wheat, alfalfa, cotton, rice, barley, potato, tomato, and millet.  
     
     
         7 . A method for providing a positive growth advantage in a target plant cell comprising introducing into the target plant cell an isolated plant geminivirus replicase polypeptide.  
     
     
         8 . The method of  claim 7  wherein the geminivirus replicase polypeptide is wheat dwarf virus Replicase.  
     
     
         9 . The method of  claim 8  wherein the geminivirus replicase polypeptide is RepA.  
     
     
         10 . The method of  claim 7  wherein the plant cell is a monocot or a dicot.  
     
     
         11 . The method of  claim 10  wherein the plant cell is from corn, soybean, sunflower, sorghum, canola, wheat, alfalfa, cotton, rice, barley, potato, tomato, and millet.  
     
     
         12 . A method for modulating cell division of a target plant cell capable of dividing, comprising introducing into the target plant cell an isolated viral replicase polypeptide.  
     
     
         13 . The method of  claim 12  wherein the polypeptide is wheat dwarf virus Replicase.  
     
     
         14 . The method of  claim 13  wherein the polypeptide is RepA.  
     
     
         15 . The method of  claim 12  wherein the plant cell is from a monocot or a dicot plant.  
     
     
         16 . The method of  claim 15  wherein the plant cell is from corn, soybean, sunflower, sorghum, canola, wheat, alfalfa, cotton, rice, barley, potato, tomato, and millet.

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