Method of using geranium oil and sophora root extracts as a supporting composition in cancer treatments

Abstract

The present invention relates to a method of use involving the administration of the herbal composition, comprising geranium oil and extracts from roots of the plants of the genus Sophora, to mammalian animals undergoing cancer treatments that would induce the bone marrow suppression side effect, such as chemotherapy and radiation therapy. The composition can take on the form of an oil capsule, tablets, pills, and pastes etc. to be administered orally at specific dosages. The composition can also take on the form of an injection to be administered intravenously and intraperitoneally at specific dosages. The administration can be made before and or after the cancer treatment.

What is claimed is:  
     
         1 . A method for administering a composition comprising the steps of 
 (a) locating one or more mammalian animals being treated with one or more cancer treatments;    (b) preparing a therapeutically effective dosage of said composition, wherein said composition comprises geranium oil and extractions from roots of  Sophora flavescenes ; and    (c) delivering said dosage of said composition to said one or more mammalian animals being treated with said one or more cancer treatments.    
     
     
         2 . The method of  claim 1 , wherein said one or more mammalian animals are one or more humans.  
     
     
         3 . The method of  claim 1 , wherein said one or more mammalian animals are one or more canines.  
     
     
         4 . The method of  claim 1 , wherein said one or more mammalian animals are one or more monkeys.  
     
     
         5 . The method of  claim 1 , wherein said one or more mammalian animals are non-rodents.  
     
     
         6 . The method of  claim 1 , wherein said one or more mammalian animals are rodents.  
     
     
         7 . The method of  claim 6 , wherein said rodents are mice.  
     
     
         8 . The method of  claim 6  wherein said rodents are rats.  
     
     
         9 . The method of  claim 6 , wherein said rodents are rabbits.  
     
     
         10 . The method of  claim 6 , wherein said rodents are hamsters.  
     
     
         11 . The method of claim of  1 , wherein said one or more cancer treatments induce a bone marrow suppression side effect.  
     
     
         12 . The method of  claim 1 , wherein said one or more cancer treatments induce a leukopenia side effect.  
     
     
         13 . The method of  claim 1 , wherein said one or more cancer treatments involve the administration of one or more chemotherapeutic agents.  
     
     
         14 . The method of  claim 13 , wherein said chemotherapeutic agent induces the bone marrow suppression side effect.  
     
     
         15 . The method of  claim 13 , wherein said chemotherapeutic agent induces the leukopenia side effect.  
     
     
         16 . The method of  claim 13 , wherein said chemotherapeutic agent is 5-Fluorouracil.  
     
     
         17 . The method of  claim 13 , wherein said chemotherapeutic agent is doxorubincin.  
     
     
         18 . The method of  claim 1 , wherein said one or more cancer treatments involve radiation therapy.  
     
     
         19 . The method of  claim 1 , wherein said geranium oil is extracted from one or more species of the genus Pelargonium.  
     
     
         20 . The method of  claim 1 , wherein said geranium oil is extracted from a plant of the genus Pelargonium and species graveolens.  
     
     
         21 . The method of  claim 1 , wherein said geranium oil is extracted from a plant of the genus Pelargonium and species roseum.  
     
     
         22 . The method of  claim 1 , wherein said geranium oil is extracted from a plant of the genus Pelargonium and species terebinthinceum.  
     
     
         23 . The method of  claim 1 , wherein said composition comprises of citronellol, geraniol, geranyl formate, citronellyl formate, matrine, and oxymatrine.  
     
     
         24 . The method of  claim 1 , wherein said extractions is from root of one or more plants of the genus Sophora.  
     
     
         25 . The method of  claim 1 , wherein said composition comprises of citronellol, geraniol, geranyl formate, citronellyl formate, linalool, Trans-Rose Oxide, Cis-Rose Oxide, kurarinol, matrine, oxymatrine, and sophocarpine.  
     
     
         26 . The method of  claim 1 , wherein said composition comprises of geranium oil, matrine and oxymatrine.  
     
     
         27 . The method of  claim 1 , wherein said composition comprises of citronellol, geraniol, citronellyl formate, geranyl formate and extractions from root of at least one plant selected from a group comprising  Sophora flavescenes, Sophora tonkinensis, Sophora subprostrata, Sophora alopecuroides, Sophora moorcroftiana , and  Euchresta strigillosa.    
     
     
         28 . The method of  claim 1 , wherein said composition comprises of A and B wherein A is selected from a group consisting of hexanol, 3-hexen-1-ol, α-pinene, β-pinene, P-cymene, limonene, 1,8-cineol, ocimene, linallol oxide, linallol, trans-rose oxide, cis-rose oxide, citronellal, menthone, iso-methone, menthol, terpineol, citronellol, geraniol, citronellyl formate, geranyl formate, caryophellene, citronellyl propinoate, gurjunene, cadiene, and B is selected from a group consisting of matrine, oxymatrine, sophoranol, N-methylcytisine, anagyrine, baptifoline, sophocarpine, sophoridine, iso matrine, 7, 11-Dehydromatrine, sophoramine, 7-Dehydrosophoramine, 9α-Hyroxy-Sophoramine, 5α,9α-Dihydroxymatrine, N-Oxysophocarpine, sophoranol N-oxide, rhombifoline, Lupanine, Mamanine, Kuraramine, Isokuraramine, and Kurarinol.  
     
     
         29 . The method of  claim 1 , wherein said composition further comprises a pharmaceutically acceptable solvent.  
     
     
         30 . The method of  claim 29 , wherein said pharmaceutically acceptable solvent comprises a mixture of about 0.025% Tween 80 in about 5% Dextrose.  
     
     
         31 . The method of  claim 29 , wherein said pharmaceutically acceptable solvent comprises a mixture of about 0.026% to about 20% Tween 80 in about 5% Dextrose.  
     
     
         32 . The method of  claim 1 , wherein said composition further comprises a pharmaceutically acceptable carrier.  
     
     
         33 . The method of  claim 32 , wherein said pharmaceutically acceptable carrier is water.  
     
     
         34 . The method of  claim 1 , wherein said step of delivering said dosage of said composition is carried out by delivering the composition to the mammalian animals before they are being treated with said one or more cancer treatments.  
     
     
         35 . The method of  claim 1 , wherein said step of delivering said dosage of said composition is carried out by delivering the composition to the mammalian animals before and after they are being treated with said one or more cancer treatments.  
     
     
         36 . The method of  claim 1 , wherein said step of delivering said dosage of said composition is carried out by delivering the composition to the mammalian animals after they are being treated with said one or more cancer treatments.  
     
     
         37 . The method of  claim 1 , wherein said step of delivering said dosage of said composition is carried out by orally administering said composition to the one or more mammalian animals.  
     
     
         38 . The method of  claim 37 , wherein said dosage is in a range of between about 9,828 mg/60 kg/day and about 900 mg/60 kg/day.  
     
     
         39 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering an oil capsule comprising said composition to the one or more mammalian animals.  
     
     
         40 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering a tablet comprising said composition to the one or more mammalian animals.  
     
     
         41 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering a pill comprising said composition to the one or more mammalian animals.  
     
     
         42 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering pastes comprising said composition to the one or more mammalian animals.  
     
     
         43 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering food additives comprising said composition to the one or more mammalian animals.  
     
     
         44 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering a dietary supplement comprising said composition to the one or more mammalian animals.  
     
     
         45 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering health food comprising said composition to the one or more mammalian animals.  
     
     
         46 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering a liquid comprising said composition to the one or more mammalian animals.  
     
     
         47 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering a syrup comprising said composition to the one or more mammalian animals.  
     
     
         48 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering decoction soup comprising said composition to the one or more mammalian animals.  
     
     
         49 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering edible forms of Pelargonium plant and roots of at least one plant selected from a group comprising  Sophora flavescenes, Sophora tonkinensis, Sophora subprostrata, Sophora alopecuroides, Sophora moorcroftiana , and  Euchresta strigillosa.    
     
     
         50 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering edible geranium oil and extractions of roots of at least one plant selected from a group comprising  Sophora flavescenes, Sophora tonkinensis, Sophora subprostrata, Sophora alopecuroides, Sophora moorcroftiana , and  Euchresta strigillosa.    
     
     
         51 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering geranium oil and powder of roots of at least one plant selected from a group comprising  Sophora flavescenes, Sophora tonkinensis, Sophora subprostrata, Sophora alopecuroides, Sophora moorcroftiana , and  Euchresta strigillosa.    
     
     
         52 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering geranium oil and pastes made from roots of at least one plant selected from a group comprising  Sophora flavescenes, Sophora tonkinensis, Sophora subprostrata, Sophora alopecuroides, Sophora moorcroftiana , and  Euchresta strigillosa.    
     
     
         53 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering geranium oil and soup mixture from decocting roots of at least one plant selected from a group comprising  Sophora flavescenes, Sophora tonkinensis, Sophora subprostrata, Sophora alopecuroides, Sophora moorcroftiana , and  Euchresta strigillosa.    
     
     
         54 . The method of  claim 37 , wherein said step of orally administering said composition is carried out by administering extractions from roots of roots of at least one plant selected from a group comprising  Sophora flavescenes, Sophora tonkinensis, Sophora subprostrata, Sophora alopecuroides, Sophora moorcroftiana , and  Euchresta strigillosa  and soup mixture from decocting Pelargonium plant.  
     
     
         55 . The method of claims  37 ,  39 ,  40 ,  41 ,  42 ,  43 ,  44 ,  45 ,  46 ,  47 ,  48 ,  49 ,  50 ,  51 ,  52 ,  53 , or  54  wherein said composition has a ratio with geranium oil in the range of between about 97.5% and about 99.5% and extractions from roots of  Sophora flavescenes  in the range of between about 2.5% and about 0.5%.  
     
     
         56 . The method of  claim 1 , wherein said step of delivering said dosage of said composition is carried out by administering intraperitoneally said composition to the one or more mammalian animals.  
     
     
         57 . The method of  claim 56 , wherein said dosage is in a range of between about 1,344 mg/60 kg/day and about 150 mg/60 kg/day.  
     
     
         58 . The method of  claim 1 , wherein said step of delivering said dosage of said composition is carried out by administering intravenously said composition to the one or more mammalian animals.  
     
     
         59 . The method of  claim 58 , wherein said dosage is in a range of between about 588 mg/60 kg/day and about 150 mg/60 kg/day.  
     
     
         60 . The method of claims  56  or  58 , wherein said composition has a ratio with geranium oil in the range of between about 99.15% and about 99.38% and extractions from roots of  Sophora flavescenes  in the range of between about 0.62% and about 0.85%.  
     
     
         61 . A method for administering a composition comprising the steps of: 
 (a) locating one or more mammalian animals being treated with one or more cancer treatments;    (b) preparing a dosage in the range of between about 25 mg/kg/day to about 100/mg/kg/day of said composition, wherein said composition comprises geranium oil and extractions from root of  Sophora flavescenes ; and    (c) delivering said dosage of said composition to said one or more mammalian animals being treated with said one or more cancer treatments.    
     
     
         62 . The method of  claim 61 , wherein said dosage is 50 mg/kg/day.  
     
     
         63 . The method of  claim 61 , wherein said cancer treatment is 5-Fluorouracil.  
     
     
         64 . A method for administering a composition comprising the steps of: 
 (a) locating one or more mammalian animals being treated with one or more cancer treatments;    (b) preparing a therapeutically effective dosage of said composition, wherein said composition comprises geranium oil and extractions from roots of  Sophora flavescenes ; and    (c) delivering said geranium oil and extractions from roots of  Sophora flavescenes  separately at an interval of one to fourteen days to said one or more mammalian animals being treated with said one or more cancer treatments.    
     
     
         65 . The method of  claim 64 , wherein said interval is within forty-eight hours.  
     
     
         66 . The method of  claim 64 , wherein said interval is within twenty-four hours.  
     
     
         67 . The method of  claim 64 , wherein said extractions are from roots of at least one plant selected from a group comprising  Sophora flavescenes, Sophora tonkinensis, Sophora subprostrata, Sophora alopecuroides, Sophora moorcroftiana , and  Euchresta strigillosa.