Creatine ester pronutrient compounds and formulations

Abstract

The present invention describes a method for providing creatine to an animal which includes receiving a creatine ester by the animal. The creatine ester is suitable for being modified by the animal to form creatine.

What is claimed is:  
     
         1 . A method for providing creatine to an animal, comprising: 
 receiving a creatine ester by the animal, wherein the creatine ester is suitable for being modified by the animal to form creatine.    
     
     
         2 . The method as described in  claim 1 , wherein the creatine ester is suitable for being formed in a solid form capable of being ingested by the animal.  
     
     
         3 . The method as described in  claim 2 , wherein the solid form includes the creatine ester and at least one of dextrose and phosphate.  
     
     
         4 . The method as described in  claim 2 , wherein the solid form is configured as at least one of a tablet and a capsule.  
     
     
         5 . The method as described in  claim 1 , wherein the creatine ester is suitable for liquid delivery.  
     
     
         6 . The method as described in  claim 5 , wherein the creatine ester includes at least one of an aqueous solution and emulsion.  
     
     
         7 . The method as described in  claim 1 , wherein the creatine ester includes at least one of creatine ethyl ester, creatine benzyl ester, creatine phosphoester, monocreatine glycerol, t-butyl creatine ester, dicreatine glycerol and tricreatine glycerol.  
     
     
         8 . The method as described in  claim 1 , wherein the creatine ester is received by the animal, the creatine ester is modified by the animal into creatine and an alcohol.  
     
     
         9 . The method as described in  claim 8 , wherein the creatine ester is modified by the animal into creatine and alcohol by an esterase.  
     
     
         10 . The method as described in  claim 8 , wherein the creatine ester is modified by at least one of an intestinal lumen, epithelial cell and blood of the animal into creatine.  
     
     
         11 . The method as described in  claim 1 , further comprising forming a creatine ester, wherein an acid moiety of creatine is modified to provide an ester bond.  
     
     
         12 . The method as described in  claim 1 , wherein the animal includes a human and livestock.  
     
     
         13 . A food supplement, comprising: 
 a creatine ester suitable for being modified by an animal to form creatine.    
     
     
         14 . The food supplement as described in  claim 13 , wherein the creatine ester is suitable for being formed in a solid form capable of being ingested by the animal.  
     
     
         15 . The food supplement as described in  claim 14 , wherein the solid form includes the creatine ester and at least one of dextrose and phosphate.  
     
     
         16 . The food supplement as described in  claim 14 , wherein the solid form is configured as at least one of a tablet and a capsule.  
     
     
         17 . The food supplement as described in  claim 13 , wherein the creatine ester is suitable for liquid delivery.  
     
     
         18 . The food supplement as described in  claim 17 , wherein the creatine ester includes at least one of an aqueous solution and emulsion.  
     
     
         19 . The food supplement as described in  claim 13 , wherein the creatine ester includes at least one of creatine ethyl ester, creatine benzyl ester, creatine phosphoester, monocreatine glycerol, t-butyl creatine ester, dicreatine glycerol and tricreatine glycerol.  
     
     
         20 . The food supplement as described in  claim 13 , wherein the creatine ester is received by the animal, the creatine ester is modified by the animal into creatine and an alcohol.  
     
     
         21 . The food supplement as described in  claim 20 , wherein the creatine ester is modified by the animal into creatine and alcohol by an esterase.  
     
     
         22 . The food supplement as described in  claim 20 , wherein the creatine ester is modified by at least one of an intestinal lumen, epithelial cell and blood of the animal into creatine.  
     
     
         23 . The food supplement as described in  claim 13 , further comprising forming a creatine ester, wherein an acid moiety of creatine is modified to provide an ester bond.  
     
     
         24 . The food supplement as described in  claim 13 , wherein the animal includes at least one of human and livestock.  
     
     
         25 . A method for providing creatine to an animal, comprising: 
 receiving an ester derivative of creatine by the animal, wherein the ester derivative of creatine is suitable for acting as a pronutrient in an animal.    
     
     
         26 . The method as described in  claim 25 , wherein the ester derivative of creatine acts as a pronutrient in the gastrointestinal tract of the animal.  
     
     
         27 . The method as described in  claim 25 , wherein the pronutrient is metabolized by the animal to form creatine.  
     
     
         28 . The method as described in  claim 27 , wherein the pronutrient is metabolized by an esterase.  
     
     
         29 . The method as described in  claim 28 , wherein the pronutrient is metabolized by esterases in at least one of an intestinal lumen, epithelial cell and blood.  
     
     
         30 . The method as described in  claim 25 , wherein the pronutrient is metabolized by the animal for form an alcohol.  
     
     
         31 . The method as described in  claim 25 , wherein the creatine ester is suitable for being formed in a solid form capable of being ingested by the animal.  
     
     
         32 . The method as described in  claim 31 , wherein the solid form includes the creatine ester and at least one of dextrose and phosphate.  
     
     
         33 . The method as described in  claim 31 , wherein the solid form is configured as at least one of a tablet and a capsule.  
     
     
         34 . The method as described in  claim 25 , wherein the creatine ester is suitable for liquid delivery.  
     
     
         35 . The method as described in  claim 34 , wherein the creatine ester includes at least one of an aqueous solution and emulsion.  
     
     
         36 . The method as described in  claim 25 , wherein the creatine ester includes at least one of creatine ethyl ester, creatine benzyl ester, creatine phosphoester, monocreatine glycerol, t-butyl creatine ester, dicreatine glycerol and tricreatine glycerol.  
     
     
         37 . The method as described in  claim 25 , wherein the creatine ester is received by the animal, the creatine ester is modified by the animal into creatine and an alcohol.  
     
     
         38 . The method as described in  claim 37 , wherein the creatine ester is modified by the animal into creatine and alcohol by an esterase.  
     
     
         39 . The method as described in  claim 37 , wherein the creatine ester is modified by at least one of an intestinal lumen, epithelial cell and blood of the animal into creatine.  
     
     
         40 . The method as described in  claim 25 , further comprising forming a creatine ester, wherein an acid moiety of creatine is modified to provide an ester bond.  
     
     
         41 . The method as described in  claim 25 , wherein the animal includes human and livestock.  
     
     
         42 . A composition of matter, comprising:  
       
         
           
           
               
               
           
         
         wherein R represents an ester.  
       
     
     
         43 . The composition of matter as described in  claim 42 , wherein R represents an ester so as to form a composition of matter including at least one of creatine benzyl ester, creatine phosphoester, monocreatine glycerol, t-butyl creatine ester, dicreatine glycerol and tricreatine glycerol.  
     
     
         44 . The composition of matter as described in  claim 42 , wherein the composition of matter is suitable for being converted to creatine upon receipt by an animal.  
     
     
         45 . The composition of matter as described in  claim 44 , wherein upon receipt of the composition of matter by the animal, creatine and an alcohol are formed.  
     
     
         46 . The composition of matter as described in  claim 42 , wherein a salt is formed of the composition of matter.  
     
     
         47 . A method of producing a creatine pronutrient, comprising: 
 reacting at least one of an anhydrous creatine and hydrated form of creatine with an alcohol in an acidic environment, wherein a product is formed including a creatine ester pronutrient.    
     
     
         48 . The method as described in  claim 47 , wherein the hydrated form of creatine includes creatine monohydrate.  
     
     
         49 . The method as described in  claim 47 , wherein the alcohol includes at least one of ethyl alcohol and benzyl alcohol.  
     
     
         50 . The method as described in  claim 47 , wherein the acidic environment is achieved through hydrochloric acid being present.  
     
     
         51 . The method as described in  claim 47 , further comprising purifying the product.  
     
     
         52 . The method as described in  claim 51 , wherein the product is purified by solvating the product in an alcohol and then cooling to form purified creatine ester.