Methods for the treatment or prophylaxis of disease by inhibition of ornithine decarboxylase

Abstract

Methods to prevent or treat conditions or diseases treatable by inhibition of ornithine decarboxylase are disclosed.

I claim:  
     
         1 . A method for the treatment of a disease or a condition which is treatable by inhibition of ornithine decarboxylase, which comprises administration of a therapeutically active or nithine decarboxylase-inhibiting amount of a salt of 2-difluoromethyl-2,5-diaminopentanoic acid with chitosan.  
     
     
         2 . A method for the prevention of a disease or a condition which is preventable by inhibition of omithine decarboxylase, which comprises administration of a therapeutically active omithine decarboxylase-inhibiting amount of a salt of 2-difluoromethyl-2,5-diaminopentanoic acid with chitosan.  
     
     
         3 . The method as defined by  claim 1 , wherein a salt of 2-difluoromethyl-2,5-diaminopentanoic acid with chitosan is administered to treat a disease or condition selected from the group consisting of cancer, benign prostatic hypertrophy, protozoal in fections, actinic keratosis, and hirsutism.  
     
     
         4 . The method as defined by  claim 2 , wherein a salt of 2-difluoromethyl-2,5-diaminopentanoic acid with chitosan is administered to prevent a condition or disease selected from the group consisting of cancer, benign prostatic hypertrophy, HIV, prozoal infections, actinic keratosis, and hirsutism.  
     
     
         5 . A method wherein a salt of 2-difluoromethyl-2,5-diaminopentanoic acid with chitosan is administered topically to prevent hair growth.