US2004009140A1PendingUtilityA1

Skin pore minimizers and skin elasticity improvers

Priority: Oct 12, 2000Filed: Jun 29, 2001Published: Jan 15, 2004
Est. expiryOct 12, 2020(expired)· nominal 20-yr term from priority
A61Q 19/08A61K 8/604A61P 17/16A61K 8/463A61K 8/55C07F 9/091A61K 8/602C07C 279/14A61Q 19/00
46
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Claims

Abstract

This invention relates to skin pore tighteners each of which comprises, as an active ingredient, a compound represented by the following formula: R 1 -OG   (1) wherein R 1 represents an alkyl or alkenyl group having 8 to 32 carbon atoms, and OG represents a residual group obtained by removing a hydrogen atom from a hydroxyl group of a polyhydric alcohol, monosaccharide or oligosaccharide at least one hydroxyl group of which has been sulfated or phosphatized, or a salt thereof, and also to skin elasticity improvers each of which comprises, as an active ingredient, a glyceryl ether derivative represented by the following formula: wherein R 1 represents the same group as defined above, and X 1 and X 2 each independently represents a hydrogen atom, —SO 3 OH or —PO(OH) 2 with the proviso that X 1 and X 2 are not hydrogen atoms at the same time, or a salt thereof. The skin pore tighteners according to the present invention have excellent effect in tightening skin pores and rendering them less conspicuous, while the skin elasticity improvers and skin tighteners according to the present invention have superb effect in preventing and lessening skin wrinkles and sagging. Accordingly, they are useful as ordinary cosmetic preparations, as cosmetic preparations after depilating treatment, and also as cosmetic preparations after removal of keratotic plugs.

Claims

exact text as granted — not AI-modified
1 . A skin pore tightener comprising a keratinocyte contracting agent as an active ingredient.  
     
     
         2 . A keratinocyte contracting agent comprising, as an active ingredient, a compound represented by the following formula (1):  
       R 1 -OG   (1) 
       wherein R 1  represents an alkyl or alkenyl group having 8 to 32 carbon atoms, and OG represents a residual group obtained by removing a hydrogen atom from a hydroxyl group of a polyhydric alcohol, monosaccharide or oligosaccharide at least one hydroxyl group of which has been sulfated or phosphatized, or a salt thereof:  
     
     
         3 . A skin pore tightener comprising, as an active ingredient, a compound represented by the following formula (1):  
       R 1 -OG  (1) 
       wherein R 1  represents an alkyl or alkenyl group having 8 to 32 carbon atoms, and OG represents a residual group obtained by removing a hydrogen atom from a hydroxyl group of a polyhydric alcohol, monosaccharide or oligosaccharide at least one hydroxyl group of which has been sulfated or phosphatized, or a salt thereof.  
     
     
         4 . A skin elasticity improver comprising, as an active ingredient, a glyceryl ether derivative represented by the following formula (2):  
       
         
           
           
               
               
           
         
       
       wherein R 1  represents an alkyl or alkenyl group having 8 to 32 carbon atoms, and X 1  and X 2  each independently represents a hydrogen atom, —SO 3 OH or —PO(OH) 2  with the proviso that X 1  and X 2  are not hydrogen atoms at the same time, or a salt thereof.  
     
     
         5 . A skin elasticity improver according to  claim 4 , which prevents and/or lessens skin wrinkles and sagging.  
     
     
         6 . A skin tightener comprising as an active ingredient a glyceryl ether derivative or a salt thereof as defined in  claim 4 .  
     
     
         7 . A skin pore tightening method, which comprises applying a keratinocyte contracting agent.  
     
     
         8 . A skin pore tightening method, which comprises applying to the skin a compound or a salt thereof as defined in  claim 2 .  
     
     
         9 . A method for preventing and/or lessening skin wrinkles and sagging, which comprises applying to the skin a glyceryl ether derivative or a salt thereof as defined in  claim 4 .  
     
     
         10 . A phosphatized glyceryl ether derivative represented by the following formula (3):  
       
         
           
           
               
               
           
         
       
       wherein R 2  represents isostearyl, 2-hexyldecyl, 2-heptylundecyl, 2-octyldodecyl, 2-decyltetradecyl, 2-dodecylhexadecyl, 2-tetradecyloctadecyl, 2-hexadecyleicosyl or 2-(1,3,3-trimethylbutyl)-5,7,7-trimethyloctyl, or a salt thereof.

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