Brain-protective agent

Abstract

A brain-protective agent containing an NF-κB decoy. In brain diseases, the brain can be particularly effectively protected against brain disorders (for example, cerebral vasospasm following a subrachnoidal hemorrhage and apoptosis of the nerve cells following a cerebrovasucular accident or serious head injury) caused by the undesired activation of cytokines or cell adhesion factors which are regulated by NF-κB by administering the brain-protective agent containing an NF-κB decoy, i.e., a compound antadonistic specifically to a nucleic acid to which NF-κB binds.

1 . A brain-protective agent comprising an NF-κB decoy.  
     
     
         2 . The brain-protective agent according to  claim 1  for the brain disorder arising from encephalopathy.  
     
     
         3 . The brain-protective agent according to  claim 2  wherein the encephalopathy is a cerebrovascular accident.  
     
     
         4 . The brain-protective agent according to  claim 2  wherein the brain disorder arising from encephalopathy is cerebral vasospasm associated with subarachnoid hemorrhage.