Process for depositing strong adherend polymer coating onto an electrically conductive surface

Abstract

Process for depositing by electrografting a strong adherent polymer coating onto an electrically conductive surface comprising the step of electrochemical grafting of an active monomer for forming a primer coating P onto the surface and having as general formula: X0 (meth)acrylate wherein X is either part of a preformed polymer or is an intermediate agent for polyaddition reaction or is an anchoring group for attachment of a molecule having at least one complementary reactive group. Such process allows formation of new primer by one-step electro-grafting of a macromonomer. Such process also allows further modification of an initial electrografted polymer to increase the coating thickness by the grafting-from technique. Such process also allows to graft onto the primer coating compounds like functional polymer, peptide, protein, oligonucleotide, dyes, drugs, anti-bacterian compounds.

1 . A process for depositing by electro-grafting a strong adherent polymer coating onto an electrically conductive surface comprising the step of electrochemically grafting an active monomer at said surface for forming a primer coating P onto said surface, said monomer having as general formula of:  
       
         
           
           
               
               
           
         
         wherein R represents hydrogen or methyl  
         and said monomer comprises an X group which is part of a preformed polymer or  
         is as an intermediate agent for polyaddition reaction or  
         is an anchoring group for attachment of a molecule having at least one complementary reactive group.  
       
     
     
         2 . The process according to  claim 1  wherein X is an intermediate agent of polyaddition.  
     
     
         3 . The process according to  claim 2  wherein the intermediate agent is an initiator for radical polymerization via nitroxyde radical(NMP) reacting with a second monomer for forming a polymer top coating TC.  
     
     
         4 . The process according to  claim 3  wherein the initiator is an alkoxyamine for the initiation of styrene polymerization.  
     
     
         5 . The process according to  claim 4  wherein the monomer is 1-acryloxy-2phenyl-2(2′,2′,6′,6′-tetramethyl-1′piperidinyloxy)ethane.  
     
     
         6 . The process according to  claim 2  wherein the intermediate agent is an initiator for radical polymerization via atom transfer polymerisation(ATRP) reacting with a second monomer for forming a polymer top coating TC.  
     
     
         7 . The process according to  claim 6  wherein the monomer is (2-chloroproprionate of ethyl acrylate for forming poly(2-chloroproprionate) ethyl acrylate as primer coating P.  
     
     
         8 . The process according to  claim 6  further comprising a metallic complex to catalyse the atom transfer polymerization for forming a polymer top coating TC.  
     
     
         9 . The process according to  claim 8  wherein the polymer top coating is polyester.  
     
     
         10 . The process according to  claim 2  wherein the intermediate agent is an initiator or a transfer agent for reversible-addition-fragmentation (RAFT) for forming a polymer top coating TC.  
     
     
         11 . The process according to  claim 1  wherein the intermediate agent is an initiator for ring opening polymerisation(ROP) reacting with a second monomer for forming a polymer top coating TC.  
     
     
         12 . The process according to  claim 11  wherein X is an alkoxide, preferably, an aluminum alkoxide.  
     
     
         13 . The process according to  claim 12  wherein the monomer is ethyl acrylate.  
     
     
         14 . The process according to  claim 13  wherein the second monomer is ε-caprolactone for forming poly(ε-caprolactone) as polymer top coating.  
     
     
         15 . The process according to  claim 12  wherein the second monomer is D,L-lactide for forming poly(D,L-lactide as polymer top coating.  
     
     
         16 . The process according to  claim 1  wherein X is part of a preformed polymer.  
     
     
         17 . The process according to  claim 16  wherein the preformed polymer is biocompatible and/or biodegradable.  
     
     
         18 . The process according to  claim 17  wherein the preformed polymer is (homopoly(4-(acryloyloxy)-ε-caprolactone)(polyACL).  
     
     
         19 . The process according to  claim 14  wherein the preformed polymer is polyethyleneoxide diacrylate.  
     
     
         20 . The process according to  claim 1  wherein the X is an anchoring group for attachment of a molecule or a macromolecule having at least one complementary reactive group.  
     
     
         21 . The process according to  claim 20  for the attachement of a macromolecule forming a polymer top coating.  
     
     
         22 . The process according to  claim 20  wherein the complementary reactive group is an amino group.  
     
     
         23 . The process according to  claim 20  wherein X is N-acryloyloxy succinimide.  
     
     
         24 . The process according to  claim 23  wherein the macromolecule is polystyrene containing amino groups.  
     
     
         25 . The process according to  claim 24  wherein the top coating is poly(meta (isopropyl-2-amino)styrene-co-styrene).  
     
     
         26 . The polymer coating on an electrically conductive surface obtained by the process according to  claim 1 .  
     
     
         27 . The polymer coating according to  claim 26  having an adhesion strength superior to 3700 N/m.  
     
     
         28 . The polymer coating according to  claim 26  having a thickness superior to one micron.  
     
     
         29 . Use of the polymer coating obtained by the process according to  claim 1  for a metallic prosthese.  
     
     
         30 . The use according to  claim 29  for a stent.  
     
     
         31 . The use of the polymer coating obtained by the process according to  claim 1  as barrier coatings.  
     
     
         32 . The use of the polymer coating obtained by the process according to  claim 1  as insulating layers.  
     
     
         33 . The use of the polymer coating obtained by the process according to  claim 1  as anti-scratching.