Pharmaceutical composition containing inhibitors of interferon-gamma

Abstract

The present invention provides compositions and methods for promoting the healing of wounds or fibrotic disorders with reduced scarring, comprising inhibitors and inhibiting IFN-γ, together with compositions and methods for promoting the healing of chronic wounds, comprising stimulating and stimulators of IFN-γ.

1 - 24 . (Cancel).  
     
     
         25 . A method for promoting the healing of a chronic wound in a patient comprising administering to said patient an amount of a stimulator of IFN-γ sufficient to effect the promotion of healing of said chronic wound.  
     
     
         26 . The method according to  claim 25 , wherein said stimulator of IFN-γ is administered to a site of wounding.  
     
     
         27 . The method according to  claim 25 , wherein between 7,500 and 15,000 IU IFN-γ is administered.  
     
     
         28 . The method according to  claim 25  wherein said stimulator of IFN-γ is selected from the group consisting of IFN-γ and a partially modified form of IFN-γ.  
     
     
         29 . The method according to  claim 25  wherein the stimulator of IFN-γ is administered in combination with a pharmaceutically acceptable carrier, diluent or excipient.