Connector and system for mixing substance

Abstract

A connector useful for combining the contents of a pair of containers which includes a hollow body for passing fluids between the containers. The body includes top and bottom end portions dimensioned to receive open-ended containers in an interference fit. The top end portion includes one or more recesses sized and arranged to facilitate drainage of a fluid from the first container into the second container when the first container is positioned above the second container. A middle portion is positioned between and adjoins the end portions of the body. A system for combining the contents of a pair of containers is formed when containers having substances to be combined are fitted onto the end portions of the connector.

1 . A connector for use in combining the contents of a pair of containers, the connector having an elongated body which comprises: 
 inner and outer surfaces, the inner surface defining a conduit through the body;    top and bottom end portions dimensioned to receive open ends of first and second containers, respectively, in an interference fit, the top end portion having an end surface which includes one or more recesses sized and arranged to facilitate drainage of a fluid from the first container into the second container by means of the conduit when the containers are fitted onto the end portions and the first container is positioned above the second container; and    a middle portion positioned between and adjoining the end portions.    
   
   
       2 . The connector of  claim 1 , wherein the end surface of the top end portion is inwardly beveled to facilitate drainage of a fluid through the conduit when the first and second containers are fitted onto the top and bottom end portions, respectively, and when the first container is positioned above the second container.  
   
   
       3 . The connector of  claim 1  further comprising a collar having a radial wall extending outwardly from and generally perpendicular to the outer surface of the middle portion, the radial wall having top and bottom surfaces.  
   
   
       4 . The connector of  claim 3 , wherein the radial wall has a peripheral end surface adapted for manual manipulation.  
   
   
       5 . The connector of  claim 3 , wherein the collar further comprises a peripheral end wall, and wherein the radial wall distally terminates at and generally perpendicular to an inner surface of the peripheral end wall.  
   
   
       6 . The connector of  claim 5 , wherein the peripheral end wall has an outer surface comprising a series of spaced-apart ridges for gripping.  
   
   
       7 . The connector of  claim 5 , wherein the collar includes a plurality of spaced-apart support walls which extend from and generally perpendicular to at least one of the top and bottom surfaces of the radial wall and which extend radially outwardly from the outer surface of the middle portion to the inner surface of the peripheral end wall.  
   
   
       8 . The connector of  claim 5 , wherein the body has a generally cylindrical shape and the peripheral end wall has a generally annular shape.  
   
   
       9 . The connector of  claim 1 , wherein the top end portion proximally terminates at a top shelf defined by a top surface of the middle portion, wherein the top shelf is sized and arranged so that a top surface at the open end of the first container is in touching contact with the top shelf when the first container is fitted onto the top end portion.  
   
   
       10 . The connector of  claim 9 , wherein the bottom end portion proximally terminates at a bottom shelf defined by a bottom surface of the middle portion, wherein the bottom shelf is sized and arranged so that a top surface at the open end of the second container is in touching contact with the bottom shelf when the second container is fitted onto the bottom end portion.  
   
   
       11 . The connector of  claim 3 , wherein at least one of the end portions proximally terminates at the top or bottom surface of the radial wall, such that a top surface at the open end of at least one of the first and second containers contacts the top or bottom surface of the radial wall when the first and second containers are fitted onto the end portions.  
   
   
       12 . The connector of  claim 1 , wherein the connector is formed as a unitary piece from a thermoplastic elastomer or a thermoplastic rubber.  
   
   
       13 . A connector for use in combining the contents of a pair of containers, the connector comprising: 
 an elongated body having inner and outer surfaces, the inner surface defining a conduit through the body, wherein the body includes: 
 an upper end portion dimensioned to receive an open end of a first container in an interference fit; and  
 a lower end portion adjoining the upper end portion;  
   a collar having a peripheral end wall and a radial wall which extends from and generally perpendicular to an outer surface of the lower end portion and which distally terminates at and generally perpendicular to an inner surface of the peripheral end wall;    a skirt depending from a bottom surface of the peripheral end wall, the skirt being dimensioned to receive an open end of a second container in an interference fit,    wherein the upper end portion has an end surface which includes one or more recesses sized and arranged to facilitate drainage of a fluid from the first container into the second container by means of the conduit when the first container is fitted onto the upper end portion and the second container is fitted onto the skirt and when the first container is positioned above the second container.    
   
   
       14 . The connector of  claim 13 , wherein the end surface of the upper end portion is inwardly beveled to facilitate drainage of a fluid through the conduit when the first and second containers are fitted onto the upper end portion and the skirt, respectively, and the first container is positioned above the second container.  
   
   
       15 . The connector of  claim 13 , wherein the peripheral end wall has an outer surface comprising a series of spaced-apart ridges for gripping.  
   
   
       16 . The connector of  claim 13 , wherein the collar includes a plurality of spaced-apart support walls which extend from and generally perpendicular to a top surface of the radial wall and which extend radially outwardly from the outer surface of the lower end portion to the inner surface of the peripheral end wall.  
   
   
       17 . The connector of  claim 13 , wherein the upper end portion proximally terminates at a top shelf defined by a top surface of the lower end portion, wherein the top shelf is sized and arranged so that a top surface at the open end of the first container is in touching contact with the top shelf when the first container is fitted onto the upper end portion.  
   
   
       18 . The connector of  claim 13 , wherein the skirt proximally terminates at a bottom shelf defined by the bottom surface of the peripheral end wall, wherein the bottom shelf is sized and arranged so that a top surface at the open end of the second container is in touching contact with the bottom shelf when the second container is fitted onto the skirt.  
   
   
       19 . The connector of  claim 17 , wherein the skirt proximally terminates at a bottom shelf defined by the bottom surface of the peripheral end wall, wherein the bottom shelf is sized and arranged so that a top surface at the open end of the second container is in touching contact with the bottom shelf when the second container is fitted onto the skirt.  
   
   
       20 . The connector of  claim 13 , wherein the upper end portion proximally terminates at a top surface of the radial wall, such that a top surface at the open end of the first container contacts the top surface of the radial wall when the first container is fitted onto the upper end portion.  
   
   
       21 . The connector of  claim 13 , wherein the body has a generally cylindrical shape and the peripheral end wall has a generally annular shape.  
   
   
       22 . The connector of  claim 13 , wherein the connector is formed as a unitary piece from a thermoplastic elastomer or a thermoplastic rubber.  
   
   
       23 . A closed system comprising: 
 the connector of  claim 1;     a first container provided with a first substance and having an inner surface, wherein the inner surface of the first container is in an interference fit with the outer surface of the top end portion of the connector when an open end of the first container is fitted onto the top end portion of the connector; and    a second container provided with a second substance and having an inner surface, wherein the inner surface of the second container is in an interference fit with the outer surface of the bottom end portion of the connector when an open end of the second container is fitted onto the bottom end portion of the connector.    
   
   
       24 . The closed system of  claim 23 , wherein the end surface of the top end portion is inwardly beveled to facilitate drainage of a fluid through the conduit when the first container is positioned above the second container.  
   
   
       25 . The closed system of  claim 23  further comprising a collar having a radial wall extending outwardly from and generally perpendicular to the outer surface of the middle portion, the radial wall having top and bottom surfaces.  
   
   
       26 . The closed system of  claim 25 , wherein the radial wall has a peripheral end surface adapted for manual manipulation.  
   
   
       27 . The closed system of  claim 25 , wherein the collar further comprises a peripheral end wall, and wherein the radial wall distally terminates at and generally perpendicular to an inner surface of the peripheral end wall.  
   
   
       28 . The closed system of  claim 27 , wherein the peripheral end wall has an outer surface comprising a series of spaced-apart ridges for gripping.  
   
   
       29 . The closed system of  claim 27 , wherein the collar includes a plurality of spaced-apart support walls which extend from and generally perpendicular to at least one of the top and bottom surfaces of the radial wall and which extend radially outwardly from the outer surface of the middle portion to the inner surface of the peripheral end wall.  
   
   
       30 . The closed system of  claim 27 , wherein the body has a generally cylindrical shape and the peripheral end wall has a generally annular shape.  
   
   
       31 . The closed system of  claim 23 , wherein the top end portion proximally terminates at a top shelf defined by a top surface of the middle portion, and wherein a top surface at the open end of the first container is in touching contact with the top shelf.  
   
   
       32 . The closed system of  claim 31 , wherein the bottom end portion proximally terminates at a bottom shelf defined by a bottom surface of the middle portion, and wherein a top surface at the open end of the second container is in touching contact with the bottom shelf.  
   
   
       33 . The closed system of  claim 25 , wherein at least one of the end portions of the connector proximally terminates at the top or bottom surface of the radial wall, such that a top surface at the open end of at least one of the first and second containers is in contact with the top or bottom surface of the radial wall.  
   
   
       34 . The closed system of  claim 23 , wherein the end surface of the top end portion includes one or more of the recesses which are generally U-shaped.  
   
   
       35 . The closed system of  claim 23 , wherein the connector is an integrally molded elastomer.  
   
   
       36 . A closed system comprising: 
 the connector of  claim 13;     a first container provided with a first substance and having an inner surface, wherein the inner surface of the first container is in an interference fit with the outer surface of the upper end portion of the connector when an open end of the first container is fitted onto the upper end portion of the connector; and    a second container provided with a second substance and having an inner surface, wherein the inner surface of the second container is in an interference fit with an outer surface of the skirt of the connector when an open end of the second container is fitted onto the skirt of the connector.    
   
   
       37 . The closed system of  claim 36 , wherein the end surface of the upper end portion is inwardly beveled to facilitate drainage of a fluid through the conduit when the first container is positioned above the second container.  
   
   
       38 . The closed system of  claim 36 , wherein the peripheral end wall has an outer surface comprising a series of spaced-apart ridges for gripping.  
   
   
       39 . The closed system of  claim 36 , wherein the collar includes a plurality of spaced-apart support walls which extend from and generally perpendicular to a top surface of the radial wall and which extend radially outwardly from the outer surface of the lower end portion to the inner surface of the peripheral end wall.  
   
   
       40 . The closed system of  claim 36 , wherein the upper end portion proximally terminates at a top shelf defined by a top surface of the lower end portion, and wherein a top surface at the open end of the first container is in touching contact with the top shelf.  
   
   
       41 . The closed system of  claim 40 , wherein the skirt proximally terminates at a bottom shelf defined by the bottom surface of the peripheral end wall, and wherein a top surface at the open end of the second container is in touching contact with the bottom shelf.  
   
   
       42 . The closed system of  claim 36 , wherein the upper end portion proximally terminates at a top surface of the radial wall, and wherein a top surface at the open end of the first container is in touching contact with the top surface of the radial wall.  
   
   
       43 . The closed system of  claim 36 , wherein the recesses are generally U-shaped.  
   
   
       44 . The closed system of  claim 36 , wherein the body has a generally cylindrical shape and the peripheral end wall has a generally annular shape.  
   
   
       45 . The closed system of  claim 36 , wherein the connector is an integrally molded elastomer.  
   
   
       46 . A kit comprising the connector of  claim 1  and first and second open-mouthed containers holding substances which can be combined.  
   
   
       47 . The kit of  claim 46 , wherein the first container holds a solvent or diluent which can be used to dissolve or dilute the substance held by the second container.  
   
   
       48 . The kit of  claim 46 , wherein the first container holds a lyophilized enzyme reagent formulation and the second container holds a buffer for reconstituting the lyophilized enzyme reagent formulation.  
   
   
       49 . The kit of  claim 48 , wherein the lyophilized enzyme reagent formulation includes a polymerase for use in amplifying a nucleic acid sequence.  
   
   
       50 . The kit of  claim 49 , wherein the polymerase is an RNA polymerase.  
   
   
       51 . A kit comprising the connector of  claim 3  and first and second open-mouthed containers holding substances which can be combined.  
   
   
       52 . The kit of  claim 51 , wherein the first container holds a solvent or diluent which can be used to dissolve or dilute the substance held by the second container.  
   
   
       53 . The kit of  claim 51 , wherein the first container holds a lyophilized enzyme reagent formulation and the second container holds a buffer for reconstituting the lyophilized enzyme reagent formulation.  
   
   
       54 . The kit of  claim 53 , wherein the lyophilized enzyme reagent formulation includes a polymerase for use in amplifying a nucleic acid sequence.  
   
   
       55 . The kit of  claim 54 , wherein the polymerase is an RNA polymerase.  
   
   
       56 . A kit comprising the connector of  claim 13  and first and second open-mouthed containers holding substances which can be combined.  
   
   
       57 . The kit of  claim 56 , wherein the first container holds a solvent or diluent which can be used to dissolve or dilute the substance held by the second container.  
   
   
       58 . The kit of  claim 56 , wherein the first container holds a lyophilized enzyme reagent formulation and the second container holds a buffer for reconstituting the lyophilized enzyme reagent formulation.  
   
   
       59 . The kit of  claim 58 , wherein the lyophilized enzyme reagent formulation includes a polymerase for use in amplifying a nucleic acid sequence.  
   
   
       60 . The kit of  claim 59 , wherein the polymerase is an RNA polymerase.