US2005008692A1PendingUtilityA1

Compositions comprising pectin and ascorbic acid

Priority: Sep 3, 2001Filed: Aug 24, 2002Published: Jan 13, 2005
Est. expirySep 3, 2021(expired)· nominal 20-yr term from priority
A61K 9/205A61P 3/02A61K 31/375A61K 9/16
55
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Claims

Abstract

Ascorbic acid compositions in the form of a powder and/or granules contain as principle components L-ascorbic acid and/or a pharmaceutically acceptable salt thereof, and a high molecular (300 kDalton or higher) pectin. The compositions are compressible into tablets with improved mechanical strength and hardness.

Claims

exact text as granted — not AI-modified
1 . A composition in the form of a powder or granules comprising: 
 (a) L-ascorbic acid and/or a pharmaceutically acceptable salt thereof,    (b) high molecular pectin.    
     
     
         2 . A composition according to  claim 1 , wherein the high molecular pectin has an average molecular weight of about 300 kDalton or higher.  
     
     
         3 . A composition according to  claim 1 , wherein the high molecular pectin has an average molecular weight of about 300 kDalton to about 400 kDalton.  
     
     
         4 . A composition according to  claim 1 , wherein the high molecular pectin has an average molecular weight of about 350 kDalton.  
     
     
         5 . A composition according to  claim 1  wherein the L-ascorbic acid and/or a pharmaceutically acceptable salt thereof is sodium L-ascorbate.  
     
     
         6 . A composition according to  claim 1 , wherein the pectin is present in quantities within the range of about 0.1% to about 10% by weight, calculated on the total weight of the composition.  
     
     
         7 . A composition according to  claim 1 , wherein the pectin is present in quantities within about 0.5% to about 2% by weight, calculated on the total weight of the composition.  
     
     
         8 . A composition according to  claim 1 , wherein said composition consists of 95-99% by weight of L-ascorbic acid and/or a pharmaceutically acceptable salt thereof and 5-1% by weight of pectin, the two components totaling 100% by weight.  
     
     
         9 . A composition according to  claim 1  in the form of a compressed tablet.  
     
     
         10 . (Canceled).  
     
     
         11 . A composition according to  claim 1  further comprising an adjuvant or excipient.  
     
     
         12 . A composition according to  claim 2  wherein the L-ascorbic acid and/or a pharmaceutically acceptable salt thereof is sodium L-ascorbate.  
     
     
         13 . A composition according to  claim 3  wherein the L-ascorbic acid and/or a pharmaceutically acceptable salt thereof is sodium L-ascorbate.  
     
     
         14 . A composition according to  claim 4  wherein the L-ascorbic acid and/or a pharmaceutically acceptable salt thereof is sodium L-ascorbate.  
     
     
         15 . A composition according to  claim 11  wherein the L-ascorbic acid and/or a pharmaceutically acceptable salt thereof is sodium L-ascorbate.  
     
     
         16 . A composition according to  claim 5 , wherein the pectin is present in quantities within the range of about 0.1% to about 10% by weight, calculated on the total weight of the composition.  
     
     
         17 . A composition according to  claim 11 , wherein the pectin is present in quantities within the range of about 0.1% to about 10% by weight, calculated on the total weight of the composition.  
     
     
         18 . A composition according to  claim 5 , wherein the pectin is present in quantities within about 0.5% to about 2% by weight, calculated on the total weight of the composition.  
     
     
         19 . A composition according to  claim 5 , wherein said composition consists of 95-99% by weight of L-ascorbic acid and/or a pharmaceutically acceptable salt thereof and 5-1% by weight of pectin, the two components totaling 100% by weight.  
     
     
         20 . A composition according to  claim 5  in the form of a compressed tablet.

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