US2005037079A1PendingUtilityA1

Temperature sensitive state-changing hydrogel composition and method for preparation

Priority: Aug 14, 2003Filed: Nov 21, 2003Published: Feb 17, 2005
Est. expiryAug 14, 2023(expired)· nominal 20-yr term from priority
A61K 8/345A61K 9/7007A61Q 19/00A61K 2800/54A61K 8/73A61K 9/06A61K 8/736A61K 2800/24A61K 8/042A61K 8/0208A61K 2800/594
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Claims

Abstract

This invention is about temperature sensitive state-changing hydrogel composition and its method of production that consists of Branched Gel Polymer 1-10 wt %, Electrolyte Gel Polymer 0.5-5 wt %, Skin-friendly Enhancements 0.5-5 wt %, Natural Bio Material 1-10 wt %, Aliphatic Polyol 3-30 wt %, Functional Additive 1-10 wt % and water 30-93 wt %. Temperature sensitive hydrogel composition is produced at temperature between 10° C. and 50° C., where hydrogel transforms to a fluid state. When this invented hydrogel composition is contacted with skin, it transforms into a fluid state owing to body temperature. Then the ingredient or medication in hydrogel can efficiently and evenly penetrate into the skin.

Claims

exact text as granted — not AI-modified
1 . Temperature sensitive state-changing hydrogel composition, comprising of; 
 (a) branched gel polymer 1-10 wt %;    (b) electrolyte gel polymer 0.5-5 wt %;    (c) skin-friendly enhancements 0.5-5 wt %;    (d) natural bio material 1-10 wt %;    (e) aliphatic polyol 3-30 wt %;    (f) functional additive 1-10 wt %; and    (g) water 30-93 wt %.    
     
     
         2 . State-changing hydrogel composition according to  claim 1 , wherein said the Branched gel polymer, one of the Hydrogel ingredient, is water soluble Polysaccharide Polymers which are selected from at least one from the group of Galactomannan, Glucomannan, Guagum, Locastgum and Plutonic.  
     
     
         3 . State-changing hydrogel composition according to  claim 1 , the Electrolyte gel polymer, one of the Hydrogel ingredient, is the Polysaccharide Polymers which are selected from at least one from the group of Aga, Algin, Carrageenan, Xantan and Gelan.  
     
     
         4 . State-changing hydrogel composition according to  claim 1 , Skin-friendly enhancer, one of the Hydrogel ingredient, is selected from at least one from the group of Polysaccharide like Chitosan, proteoglycans, Chitosan derivative, Elastin, Collagen, Hyaluronic Acid or other Proteins.  
     
     
         5 . State-changing hydrogel composition according to  claim 1 , Natural bio materials, one of the Hydrogel ingredient, is the natural substance extracted from plant, animal or mineral which are aloe, green tea, ginseng, wood vinegar, pine needles, propolis, gingko leaves, and mulberry leaves (silkworm).  
     
     
         6 . State-changing hydrogel composition according to  claim 1 , Aliphatic Polyol, one of the Hydrogel ingredients, is liquid Propylene glycol or liquid glycerine which are water soluble.  
     
     
         7 . State-changing hydrogel composition according to  claim 1 , Functional additive, one of the Hydrogel ingredient, is the additive that can provide stability and beauty care functionality. They are propilparavin, Kojic acid, α-Hydroxy acid, imidazolidinylurea, twin80 and retinol.  
     
     
         8 . Temperature Sensitive State-changing Hydrogel production method is as follows: 
 At the room temperature, mixing Aliphatic Polyol 3-30 wt % with branched gel polymer 1-10 wt % (extracted from group of Galactomannan, Glucomannan, Guagum, Locastgum and Plutonic), Electrolyte gel polymer 0.5-5 wt % (extracted from group of Aga, Aglin, Carragenan, Xantan and Gelan), Functional Additive 1-10 wt % (extracted from group of Chitosan derivative, Proteoglucan, Elastin, Collagen and Hyaluronic acid), and adding between about 30-93 wt % water;    increasing the temperature to 45˜95° C.

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