US2005059956A1PendingUtilityA1

Devices for intraocular drug delivery

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Assignee: UNIV JOHNS HOPKINSPriority: Aug 30, 2000Filed: Apr 12, 2004Published: Mar 17, 2005
Est. expiryAug 30, 2020(expired)· nominal 20-yr term from priority
Inventors:Signe VarnerEugene DejuanTerry Harrison ShelleyAaron Christopher BarnesMark Humayun
A61P 27/02A61F 9/0017A61K 9/0051A61B 2017/00867
55
PatentIndex Score
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Claims

Abstract

An therapeutic agent delivery device that can allows is particularly suitable for delivery of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. Preferred devices of the invention are minimally invasive, refillable and may be easily fixed to the treatment area. Preferred delivery devices of the invention also include those that comprise a non-linear shaped body member body housing one or more substances and a delivery mechanism for the sustained delivery of the one or more substances from the non-linear shaped body member to the patient.

Claims

exact text as granted — not AI-modified
1 - 67 . (cancelled)  
   
   
       68 . A drug delivery device comprising: 
 a non-linear shaped body member having at least two deviations from a linear and that has a shape other than a substantially C-configuration and that is implanted within a patient during use of the device to deliver a drug substance to the patient via the body member.    
   
   
       69 . The device of  claim 68  wherein the device body member comprises at least three deviations from a linear path.  
   
   
       70 . The device of  claim 68  wherein the device body member comprises at least four deviations from a linear path.  
   
   
       71 . The device of  claim 68  wherein the device body member comprises at least five deviations from a linear path.  
   
   
       72 . The device of  claim 68  wherein the device body member comprises a helical shape.  
   
   
       73 . The device of  claim 68  wherein the device body member comprises a substantially Z-shape.  
   
   
       74 . The device of  claim 68  wherein the device comprises a therapeutic agent for delivery to the patient during use of the device.  
   
   
       75 . The device of  claim 68  wherein the device body member comprises a polymer.  
   
   
       76 . The device of  claim 68  wherein the device length is about 1.5 cm or less.  
   
   
       77 . A drug delivery device comprising: 
 a coil-shaped body member that is implanted in a patient during use of the device to deliver a drug substance to the patient via the body member.    
   
   
       78 . The device of  claim 77  wherein the device comprises a therapeutic agent for delivery to the patient during use of the device.  
   
   
       79 . The device of  claim 77  wherein the device body member comprises a polymer.  
   
   
       80 . The device of  claim 77  wherein the device body member comprises a polymer that comprises a therapeutic substance to be delivered to the patient.  
   
   
       81 . The device of  claim 77  wherein the device length is about 1.5 cm or less.  
   
   
       82 . A method for treating a patient comprising: 
 (a) providing a delivery device comprising a non-linear shaped body member having at least two deviations from a linear path and that has a shape other than a substantially C-configuration; and    (b) inserting into a patient ear the device whereby the body member resides in the patient ear and a therapeutic substance is administered to the patient via the body member.    
   
   
       83 . The method of  claim 82  wherein the device body member comprises at least three deviations from a linear path.  
   
   
       84 . The method of  claim 82  wherein the device body member comprises at least four deviations from a linear path.  
   
   
       85 . The method of  claim 82  wherein the device body member comprises at least five deviations from a linear path.  
   
   
       86 . The method of  claim 82  wherein the device body member comprises a helical shape.  
   
   
       87 . The method of  claim 82  wherein the device body member comprises a substantially Z-shape.  
   
   
       88 . The method of  claim 82  wherein the device body member comprises a polymer.  
   
   
       89 . The method of  claim 82  wherein the device body member comprises a polymer that comprises a therapeutic substance to be delivered to the patient.  
   
   
       90 . The method of  claim 82  wherein the device comprises a shape memory material.  
   
   
       91 . The method of  claim 82  wherein the device length is about 1.5 cm or less.

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