US2005100955A1PendingUtilityA1

Method of diagnosing, monitoring, staging, imaging and treating colon cancer

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Priority: May 21, 1998Filed: Dec 23, 2004Published: May 12, 2005
Est. expiryMay 21, 2018(expired)· nominal 20-yr term from priority
G01N 33/57535A61K 39/0011C07K 16/18Y10T436/25C12Q 2600/136A61K 51/1063C12Q 2600/112C12Q 1/6886A61K 2039/505C07K 16/3046
52
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Claims

Abstract

The present invention provides new methods for detecting, diagnosing, monitoring, staging, prognosticating, imaging and treating colon cancer.

Claims

exact text as granted — not AI-modified
1 - 7 . (canceled)  
     
     
         8 . An antibody which specifically binds a polypeptide encoded by SEQ ID NO: 1.  
     
     
         9 . A method of imaging colon cancer in a patient comprising administering to the patient an antibody of  claim 8 .  
     
     
         10 . The method of  claim 9  wherein said antibody is labeled with paramagnetic ions or a radioisotope.  
     
     
         11 . A method of treating colon cancer in a patient comprising administering to the patient a molecule which downregulates expression or activity of CSG.  
     
     
         12 . A method of inducing an immune response against a target cell expressing CSG comprising delivering to a human patient an immunogenically stimulatory amount of a CSG protein so that an immune response is mounted against the target cell.

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